Search Results - "Marcellin, Marlene"

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1 by Imbert, Caroline, Montfort, Anne, Fraisse, Marine, Marcheteau, Elie, Gilhodes, Julia, Martin, Elodie, Bertrand, Florie, Marcellin, Marlène, Burlet-Schiltz, Odile, Peredo, Anne Gonzalez de, Garcia, Virginie, Carpentier, Stéphane, Tartare-Deckert, Sophie, Brousset, Pierre, Rochaix, Philippe, Puisset, Florent, Filleron, Thomas, Meyer, Nicolas, Lamant, Laurence, Levade, Thierry, Ségui, Bruno, Andrieu-Abadie, Nathalie, Colacios, Céline

“…Immune checkpoint inhibitors (ICIs) have dramatically modified the prognosis of several advanced cancers, however many patients still do not respond to…”
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Isotope-labeled protein standards: toward absolute quantitative proteomics by Brun, Virginie, Dupuis, Alain, Adrait, Annie, Marcellin, Marlène, Thomas, Damien, Court, Magali, Vandenesch, François, Garin, Jérôme

“…Diagnostic development and public health surveillance require technologies that provide specific identification and absolute quantification of protein…”
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The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation by Mori, Daiki, Grégoire, Claude, Voisinne, Guillaume, Celis-Gutierrez, Javier, Aussel, Rudy, Girard, Laura, Camus, Mylène, Marcellin, Marlène, Argenty, Jérémy, Burlet-Schiltz, Odile, Fiore, Frédéric, Gonzalez de Peredo, Anne, Malissen, Marie, Roncagalli, Romain, Malissen, Bernard

“…To determine the respective contribution of the LAT transmembrane adaptor and CD5 and CD6 transmembrane receptors to early TCR signal propagation,…”
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TOM1 is a PI5P effector involved in the regulation of endosomal maturation by Boal, Frédéric, Mansour, Rana, Gayral, Marion, Saland, Estelle, Chicanne, Gaëtan, Xuereb, Jean-Marie, Marcellin, Marlène, Burlet-Schiltz, Odile, Sansonetti, Philippe J, Payrastre, Bernard, Tronchère, Hélène

“…Phosphoinositides represent a major class of lipids specifically involved in the organization of signaling cascades, maintenance of the identity of organelles…”
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CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens by Blaize, Gaëtan, Daniels-Treffandier, Hélène, Aloulou, Meryem, Rouquié, Nelly, Yang, Cui, Marcellin, Marlène, Gador, Mylène, Benamar, Mehdi, Ducatez, Mariette, Song, Ki-duk, Burlet-Schiltz, Odile, Saoudi, Abdelhadi, Love, Paul E., Fazilleau, Nicolas, de Peredo, Anne Gonzalez, Lesourne, Renaud

“…CD5 is characterized as an inhibitory coreceptor with an important regulatory role during T cell development. The molecular mechanism by which CD5 operates has…”
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Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodeling by Santin, Yohan, Fazal, Loubina, Sainte-Marie, Yannis, Sicard, Pierre, Maggiorani, Damien, Tortosa, Florence, Yücel, Yasemin Yücel, Teyssedre, Lise, Rouquette, Jacques, Marcellin, Marlene, Vindis, Cécile, Shih, Jean C., Lairez, Olivier, Burlet-Schiltz, Odile, Parini, Angelo, Lezoualc’h, Frank, Mialet-Perez, Jeanne

“…Chronic remodeling postmyocardial infarction consists in various maladaptive changes including interstitial fibrosis, cardiomyocyte death and mitochondrial…”
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Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system by Ayoub, Ikram, Dauvilliers, Yves, Barateau, Lucie, Vermeulen, Thaïs, Mouton-Barbosa, Emmanuelle, Marcellin, Marlène, Gonzalez-de-Peredo, Anne, Gross, Catharina C, Saoudi, Abdelhadi, Liblau, Roland

“…Narcolepsy type 1 (NT1) is a rare, chronic and disabling neurological disease causing excessive daytime sleepiness and cataplexy. NT1 is characterized…”
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Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease by Denadai-Souza, Alexandre, Bonnart, Chrystelle, Tapias, Núria Solà, Marcellin, Marlène, Gilmore, Brendan, Alric, Laurent, Bonnet, Delphine, Burlet-Schiltz, Odile, Hollenberg, Morley D., Vergnolle, Nathalie, Deraison, Céline

“…While proteases are essential in gastrointestinal physiology, accumulating evidence indicates that dysregulated proteolysis plays a pivotal role in the…”
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Isotope-labeled Protein Standards by Brun, Virginie, Dupuis, Alain, Adrait, Annie, Marcellin, Marlène, Thomas, Damien, Court, Magali, Vandenesch, François, Garin, Jérôme

“…Diagnostic development and public health surveillance require technologies that provide specific identification and absolute quantification of protein…”
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Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function by Duguet, Fanny, Locard-Paulet, Marie, Marcellin, Marlène, Chaoui, Karima, Bernard, Isabelle, Andreoletti, Olivier, Lesourne, Renaud, Burlet-Schiltz, Odile, Gonzalez de Peredo, Anne, Saoudi, Abdelhadi

“…Regulatory T cells (Treg) represent a minor subpopulation of T lymphocytes that is crucial for the maintenance of immune homeostasis. Here, we present a…”
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Themis2 lowers the threshold for B cell activation during positive selection by Cheng, Daian, Deobagkar-Lele, Mukta, Zvezdova, Ekaterina, Choi, Seeyoung, Uehara, Shoji, Baup, Delphine, Bennett, Sophia C, Bull, Katherine R, Crockford, Tanya L, Ferry, Helen, Warzecha, Claude, Marcellin, Marlène, de Peredo, Anne Gonzalez, Lesourne, Renaud, Anzilotti, Consuelo, Love, Paul E, Cornall, Richard J

“…Cornall and colleagues show that Themis2 interacts with the phospholipase PLC-γ2 and lowers the threshold for B cell activation by low but not high avidity…”
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Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro by Bergamelli, Mathilde, Martin, Hélène, Aubert, Yann, Mansuy, Jean-Michel, Marcellin, Marlène, Burlet-Schiltz, Odile, Hurbain, Ilse, Raposo, Graça, Izopet, Jacques, Fournier, Thierry, Benchoua, Alexandra, Bénard, Mélinda, Groussolles, Marion, Cartron, Géraldine, Tanguy Le Gac, Yann, Moinard, Nathalie, D’Angelo, Gisela, Malnou, Cécile E.

“…Although placental small extracellular vesicles (sEVs) are extensively studied in the context of pregnancy, little is known about their role during viral…”
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Benchmarking quantitative label-free LC–MS data processing workflows using a complex spiked proteomic standard dataset by Ramus, Claire, Hovasse, Agnès, Marcellin, Marlène, Hesse, Anne-Marie, Mouton-Barbosa, Emmanuelle, Bouyssié, David, Vaca, Sebastian, Carapito, Christine, Chaoui, Karima, Bruley, Christophe, Garin, Jérôme, Cianférani, Sarah, Ferro, Myriam, Van Dorssaeler, Alain, Burlet-Schiltz, Odile, Schaeffer, Christine, Couté, Yohann, Gonzalez de Peredo, Anne

“…Proteomic workflows based on nanoLC–MS/MS data-dependent-acquisition analysis have progressed tremendously in recent years. High-resolution and fast sequencing…”
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Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability by Zvezdova, Ekaterina, Mikolajczak, Judith, Garreau, Anne, Marcellin, Marlène, Rigal, Lise, Lee, Jan, Choi, Seeyoung, Blaize, Gaëtan, Argenty, Jérémy, Familiades, Julien, Li, Liqi, Gonzalez de Peredo, Anne, Burlet-Schiltz, Odile, Love, Paul E, Lesourne, Renaud

“…The T cell signaling protein Themis1 is essential for the positive and negative selection of thymocytes in the thymus. Although the developmental defect that…”
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First Structural Insights into α-l-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies by Siguier, Béatrice, Haon, Mireille, Nahoum, Virginie, Marcellin, Marlène, Burlet-Schiltz, Odile, Coutinho, Pedro M., Henrissat, Bernard, Mourey, Lionel, O'Donohue, Michael J., Berrin, Jean-Guy, Tranier, Samuel, Dumon, Claire

“…α-l-Arabinofuranosidases are glycoside hydrolases that specifically hydrolyze non-reducing residues from arabinose-containing polysaccharides. In the case of…”
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In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast by Ouji, Manel, Reyser, Thibaud, Yamaryo-Botté, Yoshiki, Nguyen, Michel, Rengel, David, Dutreuil, Axelle, Marcellin, Marlène, Burlet-Schiltz, Odile, Augereau, Jean-Michel, Riscoe, Michael K., Paloque, Lucie, Botté, Cyrille, Benoit-Vical, Françoise

“…Emergence and spread of parasite resistance to artemisinins, the first-line antimalarial therapy, threaten the malaria eradication policy. To identify…”
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Colitis Linked to Endoplasmic Reticulum Stress Induces Trypsin Activity Affecting Epithelial Functions by Solà Tapias, Núria, Denadai-Souza, Alexandre, Rolland-Fourcade, Claire, Quaranta-Nicaise, Muriel, Blanpied, Catherine, Marcellin, Marlène, Edir, Anissa, Rolland, Corinne, Cirillo, Carla, Dietrich, Gilles, Alric, Laurent, Portier, Guillaume, Kirzin, Sylvain, Bonnet, Delphine, Mas, Emmanuel, Burlet-Schiltz, Odile, Deraison, Céline, Bonnart, Chrystelle, Vergnolle, Nathalie, Barreau, Frédérick

“…Abstract Background and Aims Intestinal epithelial cells [IECs] from inflammatory bowel disease [IBD] patients exhibit an excessive induction of endoplasmic…”
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Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large‐scale and targeted quantitative proteomics by Matondo, Mariette, Marcellin, Marlène, Chaoui, Karima, Bousquet‐Dubouch, Marie‐Pierre, Gonzalez‐de‐Peredo, Anne, Monsarrat, Bernard, Burlet‐Schiltz, Odile

“…The ubiquitin‐proteasome pathway (UPP) plays a critical role in the degradation of proteins implicated in cell cycle control, signal transduction, DNA damage…”
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Peptide Storage: Are You Getting the Best Return on Your Investment? Defining Optimal Storage Conditions for Proteomics Samples by Kraut, Alexandra, Marcellin, Marlène, Adrait, Annie, Kuhn, Lauriane, Louwagie, Mathilde, Kieffer-Jaquinod, Sylvie, Lebert, Dorothée, Masselon, Christophe D, Dupuis, Alain, Bruley, Christophe, Jaquinod, Michel, Garin, Jérôme, Gallagher-Gambarelli, Maighread

“…To comply with current proteomics guidelines, it is often necessary to analyze the same peptide samples several times. Between analyses, the sample must be…”
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Affinity chromatography: a valuable strategy to isolate substrates of methionine sulfoxide reductases? by Tarrago, Lionel, Kieffer-Jaquinod, Sylvie, Lamant, Tiphaine, Marcellin, Marl Ne, Garin, J R Me, Rouhier, Nicolas, Rey, Pascal

“…Reactive oxygen species fulfill key roles in development and signaling, but lead at high concentration to damage in macromolecules. In proteins, methionine…”
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