Search Results - "Marceau, Normand"

Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide‐dependent Akt and Rab5 modulation by Roux, Alexandra, Loranger, Anne, Lavoie, Josée N., Marceau, Normand

“…ABSTRACT Keratins (Ks) are epithelial cell intermediate filament (IF) proteins that are expressed as pairs in a differentiation‐regulated manner. Hepatocyte…”
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Impact of keratin intermediate filaments on insulin‐mediated glucose metabolism regulation in the liver and disease association by Roux, Alexandra, Gilbert, Stéphane, Loranger, Anne, Marceau, Normand

“…In all cells, a tight regulation exists between glucose uptake and utilization to prevent diseases related to its perturbed metabolism. In insulin‐targeted…”
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Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics by Bordeleau, François, Myrand Lapierre, Marie-Eve, Sheng, Yunlong, Marceau, Normand

“…Cell mechanical activity generated from the interplay between the extracellular matrix (ECM) and the actin cytoskeleton is essential for the regulation of cell…”
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Keratin 8/18 modulation of protein kinase C-mediated integrin-dependent adhesion and migration of liver epithelial cells by Bordeleau, François, Galarneau, Luc, Gilbert, Stéphane, Loranger, Anne, Marceau, Normand

“…Keratins are intermediate filament (IF) proteins of epithelial cells, expressed as pairs in a lineage/differentiation manner. Hepatocyte and hepatoma cell IFs…”
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Simple Epithelium Keratins 8 and 18 Provide Resistance to Fas-Mediated Apoptosis. The Protection Occurs through a Receptor-Targeting Modulation by Gilbert, Stéphane, Loranger, Anne, Daigle, Nathalie, Marceau, Normand

“…Keratins 8 and 18 belong to the keratin family of intermediate filament (IF) proteins and constitute a hallmark for all simple epithelia, including the liver…”
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Keratin 8 is required for the maintenance of architectural structure in thymus epithelium by Odaka, Chikako, Loranger, Anne, Takizawa, Kazuya, Ouellet, Michel, Tremblay, Michel J, Murata, Shigeo, Inoko, Akihito, Inagaki, Masaki, Marceau, Normand

“…Keratins (Ks), the intermediate filament (IF) proteins of epithelia, are coordinately expressed as pairs in a cell-lineage and differentiation manner. Cortical…”
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Keratins Modulate c-Flip/Extracellular Signal-Regulated Kinase 1 and 2 Antiapoptotic Signaling in Simple Epithelial Cells by Gilbert, Stéphane, Loranger, Anne, Marceau, Normand

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Measuring integrated cellular mechanical stress response at focal adhesions by optical tweezers by Bordeleau, Francois, Bessard, Judicael, Sheng, Yunlong, Marceau, Normand

“…The ability of cells to sustain mechanical stress is largely modulated by the cytoskeleton. We present a new application of optical tweezers to study cell's…”
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Keratin–protein kinase C interaction in reactive oxygen species-induced hepatic cell death through mitochondrial signaling by Mathew, Jasmin, Galarneau, Luc, Loranger, Anne, Gilbert, Stéphane, Marceau, Normand

“…Keratins (Ks), the intermediate filament (IF) proteins of epithelia, constitute at least 20 cytoskeletal proteins subdivided into type I (K9-20) and type II…”
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Uncovering the Roles of Intermediate Filaments in Apoptosis by Marceau, Normand, Gilbert, Stéphane, Loranger, Anne

“…Intermediate filament (IF) genes are differentially expressed according to cell lineage establishment and terminal cell differentiation, and in this context IF…”
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Keratin impact on PKCδ- and ASMase-mediated regulation of hepatocyte lipid raft size - implication for FasR-associated apoptosis by Gilbert, Stéphane, Loranger, Anne, Omary, M Bishr, Marceau, Normand

“…Keratins are epithelial cell intermediate filament (IF) proteins that are expressed as pairs in a cell-differentiation-regulated manner. Hepatocytes express…”
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Keratins modulate hepatic cell adhesion, size and G1/S transition by Galarneau, Luc, Loranger, Anne, Gilbert, Stéphane, Marceau, Normand

“…Keratins (Ks) are the intermediate filament (IF) proteins of epithelial cells. Hepatocyte IFs are made solely of keratins 8 and 18 (K8/K18), the hallmark of…”
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Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling by Mathew, Jasmin, Loranger, Anne, Gilbert, Stéphane, Faure, Robert, Marceau, Normand

“…As differentiated cells, hepatocytes primarily metabolize glucose for ATP production through oxidative phosphorylation of glycolytic pyruvate, whereas…”
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Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss by Gilbert, Stéphane, Ruel, Alexandre, Loranger, Anne, Marceau, Normand

“…Fas-induced apoptosis is initiated through the recruitment of FADD and procaspase 8 to form the death-inducing signaling complex (DISC). In some cells (type I…”
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Cytoskeleton keratin regulation of FasR signaling through modulation of actin/ezrin interplay at lipid rafts in hepatocytes by Gilbert, Stéphane, Loranger, Anne, Lavoie, Josée N., Marceau, Normand

“…FasR stimulation by Fas ligand leads to rapid formation of FasR microaggregates, which become signaling protein oligomerization transduction structures…”
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Keratin contribution to cellular mechanical stress response at focal adhesions as assayed by laser tweezers by Bordeleau, François, Bessard, Judicael, Sheng, Yunlong, Marceau, Normand

“…The ability of adherent cells to sense and adapt to a mechanical stress generated at focal adhesions (FAs) largely occurs through the integrin-mediated…”
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Dexamethasone and dimethylsulfoxide as distinct regulators of growth and differentiation of cultured suckling rat hepatocytes by Baribault, H, Marceau, N

“…Dexamethasone can promote the differentiation of different tissues in vivo while dimethylsulfoxide is a commonly used inducer of differentiation in various…”
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Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G αB-crystallin mutant by Chávez Zobel, Aura T., Loranger, Anne, Marceau, Normand, Thériault, Jimmy R., Lambert, Herman, Landry, Jacques

“…A familial form of desmin-related myopathy (DRM) is associated with a missense mutation (R120G) in αB-crystallin (αB) and is characterized by intracellular…”
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Dual roles of intermediate filaments in apoptosis by Marceau, Normand, Schutte, Bert, Gilbert, Stéphane, Loranger, Anne, Henfling, Mieke E.R., Broers, Jos L.V., Mathew, Jasmin, Ramaekers, Frans C.S.

“…New roles have emerged recently for intermediate filaments (IFs), namely in modulating cell adhesion and growth, and providing resistance to various forms of…”
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Keratin 8 modulation of desmoplakin deposition at desmosomes in hepatocytes by Loranger, Anne, Gilbert, Stéphane, Brouard, Jean-Simon, Magin, Thomas M., Marceau, Normand

“…Keratins, the intermediate filament proteins of epithelial cells, connect to desmosomes, the cell–cell adhesion structures at the surface membrane. The…”
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