Search Results - "Marc J. Orbach"

Recent Advances in Our Understanding of the Environmental, Epidemiological, Immunological, and Clinical Dimensions of Coccidioidomycosis by NGUYEN, Chinh, BARKER, Bridget Marie, HOOVER, Susan, NIX, David E, AMPEL, Neil M, FRELINGER, Jeffrey A, ORBACH, Marc J, GALGIANI, John N

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The WOPR family protein Ryp1 is a key regulator of gene expression, development, and virulence in the thermally dimorphic fungal pathogen Coccidioides posadasii by Mandel, M Alejandra, Beyhan, Sinem, Voorhies, Mark, Shubitz, Lisa F, Galgiani, John N, Orbach, Marc J, Sil, Anita

“…Coccidioides spp. are mammalian fungal pathogens endemic to the Southwestern US and other desert regions of Mexico, Central and South America, with the bulk of…”
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Molecular Analysis of S-morphology Aflatoxin Producers From the United States Reveals Previously Unknown Diversity and Two New Taxa by Singh, Pummi, Callicott, Kenneth A., Orbach, Marc J., Cotty, Peter J.

“…Aflatoxins are highly toxic carcinogens that detrimentally influence profitability of agriculture and the health of humans and domestic animals. Several…”
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Aspergillus texensis: A Novel Aflatoxin Producer with S Morphology from the United States by Singh, Pummi, Orbach, Marc J, Cotty, Peter J

“…Aflatoxins are carcinogenic metabolites produced primarily by fungi within section . These fungi infect a wide range of crops in warm regions. Molecular…”
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Comparative Genomics of Aspergillus flavus S and L Morphotypes Yield Insights into Niche Adaptation by Ohkura, Mana, Cotty, Peter J, Orbach, Marc J

“…, the primary causal agent for aflatoxin contamination on crops, consists of isolates with two distinct morphologies: isolates of the S morphotype produce…”
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Phenotypic Differentiation of Two Morphologically Similar Aflatoxin-Producing Fungi from West Africa by Singh, Pummi, Mehl, Hillary L, Orbach, Marc J, Callicott, Kenneth A, Cotty, Peter J

“…Aflatoxins (AF) are hepatocarcinogenic metabolites produced by several species. Crop infection by these species results in aflatoxin contamination of cereals,…”
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Discovery of a Unique Set of Dog-Seroreactive Coccidioides Proteins Using Nucleic Acid Programmable Protein Array by Koehler, Megan A, Song, Lusheng, Grill, Francisca J, Shubitz, Lisa F, Powell, Daniel A, Galgiani, John N, Orbach, Marc J, Robb, Edward J, Chung, Yunro, Williams, Stacy A, Murugan, Vel, Park, Jin-Gyoon, LaBaer, Joshua, Lake, Douglas F, Magee, D Mitchell

“…Valley Fever (VF), caused by fungi in the genus , is a prevalent disease in southwestern and western parts of the United States that affects both humans and…”
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Vaccines to Prevent Coccidioidomycosis: A Gene-Deletion Mutant of Coccidioides Posadasii as a Viable Candidate for Human Trials by Galgiani, John N, Shubitz, Lisa F, Orbach, Marc J, Mandel, M Alejandra, Powell, Daniel A, Klein, Bruce S, Robb, Edward J, Ohkura, Mana, Seka, Devin J, Tomasiak, Thomas M, Monath, Thomas P

“…Coccidioidomycosis is an endemic fungal infection that is reported in up to 20,000 persons per year and has an economic impact close to $1.5 billion. Natural…”
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Temperature Influences on Interactions Among Aflatoxigenic Species of Aspergillus Section Flavi During Maize Colonization by Ching'anda, Connel, Atehnkeng, Joseph, Bandyopadhyay, Ranajit, Callicott, Kenneth A., Orbach, Marc J., Mehl, Hillary L., Cotty, Peter J.

“…Fungal species within Aspergillus section Flavi contaminate food and feed with aflatoxins. These toxic fungal metabolites compromise human and animal health…”
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Differential Thermotolerance Adaptation between Species of Coccidioides by Mead, Heather L, Hamm, Paris S, Shaffer, Isaac N, Teixeira, Marcus de Melo, Wendel, Christopher S, Wiederhold, Nathan P, Thompson, 3rd, George R, Muñiz-Salazar, Raquel, Castañón-Olivares, Laura Rosio, Keim, Paul, Plude, Carmel, Terriquez, Joel, Galgiani, John N, Orbach, Marc J, Barker, Bridget M

“…Coccidioidomycosis, or Valley fever, is caused by two species of dimorphic fungi. Based on molecular phylogenetic evidence, the genus contains two reciprocally…”
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Genomic and Population Analyses of the Mating Type Loci in Coccidioides Species Reveal Evidence for Sexual Reproduction and Gene Acquisition by Mandel, M Alejandra, Barker, Bridget M, Kroken, Scott, Rounsley, Steven D, Orbach, Marc J

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MGOS: Development of a Community Annotation Database for Magnaporthe oryzae by KOUR, Anupreet, GREER, Kevin, VALENT, Barbara, ORBACH, Marc J, SODERLUND, Carol

“…Magnaporthe oryzae causes rice blast disease, which is the most serious disease of cultivated rice worldwide. We previously developed the Magnaporthe…”
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Development of a high throughput transformation system for insertional mutagenesis in Magnaporthe oryzae by Betts, Melania F., Tucker, Sara L., Galadima, Natalia, Meng, Yan, Patel, Gayatri, Li, Lei, Donofrio, Nicole, Floyd, Anna, Nolin, Shelly, Brown, Doug, Mandel, M. Alejandra, Mitchell, Thomas K., Xu, Jin-Rong, Dean, Ralph A., Farman, Mark L., Orbach, Marc J.

“…Towards the goal of disrupting all genes in the genome of Magnaporthe oryzae and identifying their function, a collection of >55,000 random insertion lines of…”
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Fungi have three tetraspanin families with distinct functions by Lambou, Karine, Tharreau, Didier, Kohler, Annegret, Sirven, Catherine, Marguerettaz, Mélanie, Barbisan, Crystel, Sexton, Adrienne C, Kellner, Ellen M, Martin, Francis, Howlett, Barbara J, Orbach, Marc J, Lebrun, Marc-Henri

“…Tetraspanins are small membrane proteins that belong to a superfamily encompassing 33 members in human and mouse. These proteins act as organizers of…”
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Protein Expression Profiling of Coccidioides posadasii by Two-Dimensional Differential In-Gel Electrophoresis and Evaluation of a Newly Recognized Peroxisomal Matrix Protein as a Recombinant Vaccine Candidate by Orsborn, Kris I, Shubitz, Lisa F, Peng, Tao, Kellner, Ellen M, Orbach, Marc J, Haynes, Paul A, Galgiani, John N

“…Coccidioides posadasii and Coccidioides immitis are dimorphic, soil-dwelling pathogenic ascomycetes endemic to the southwestern United States. Infection can…”
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Δcps1 vaccine protects dogs against experimentally induced coccidioidomycosis by Shubitz, Lisa F., Robb, Edward J., Powell, Daniel A., Bowen, Richard A., Bosco-Lauth, Angela, Hartwig, Airn, Porter, Stephanie M., Trinh, Hien, Moale, Hilary, Bielefeldt-Ohmann, Helle, Hoskinson, James, Orbach, Marc J., Frelinger, Jeffrey A., Galgiani, John N.

“…•There is need for a vaccine to prevent coccidioidomycosis in dogs and humans.•Δcps1, an avirulent, live vaccine, appeared safe and well-tolerated in…”
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A Chronic Murine Disease Model of Coccidioidomycosis Using Coccidioides posadasii, Strain 1038 by Shubitz, Lisa F, Powell, Daniel A, Butkiewicz, Christine D, Lewis, M Lourdes, Trinh, Hien T, Frelinger, Jeffrey A, Orbach, Marc J, Galgiani, John N

“…Abstract Murine infections with most Coccidioides spp. strains are lethal by 3 weeks, limiting the study of immune responses. Coccidioides posadasii, strain…”
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A Coccidioides posadasii CPS1 Deletion Mutant Is Avirulent and Protects Mice from Lethal Infection by Narra, Hema P, Shubitz, Lisa F, Mandel, M Alejandra, Trinh, Hien T, Griffin, Kurt, Buntzman, Adam S, Frelinger, Jeffrey A, Galgiani, John N, Orbach, Marc J

“…The CPS1 gene was identified as a virulence factor in the maize pathogen Cochliobolus heterostrophus Hypothesizing that the homologous gene in Coccidioides…”
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Genetic Transformation of "Coccidioides immitis" Facilitated by "Agrobacterium tumefaciens" by Abuodeh, Raed O., Orbach, Marc J., Mandel, M. Alejandra, Das, Anath, Galgiani, John N.

“…Agrobacterium tumefaciens was used to facilitate genetic transformation of Coccidioides immitis. A gene cassette containing the gene encoding hygromycin…”
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Viable spores of Coccidioides posadasii Δcps1 are required for vaccination and provide long lasting immunity by Shubitz, Lisa F., Powell, Daniel A., Trinh, Hien T., Lewis, M. Lourdes, Orbach, Marc J., Frelinger, Jeffrey A., Galgiani, John N.

“…Coccidioidomycosis is a systemic fungal infection for which a vaccine has been sought for over fifty years. The avirulent Coccidioides posadasii strain, Δcps1,…”
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