Search Results - "Marban, Céline"

On the way to find a cure: Purging latent HIV-1 reservoirs by Schwartz, Christian, Bouchat, Sophie, Marban, Céline, Gautier, Virginie, Van Lint, Carine, Rohr, Olivier, Le Douce, Valentin

“…[Display omitted] Introduction of cART in 1996 has drastically increased the life expectancy of people living with HIV-1. However, this treatment has not…”
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Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing by Marban, Céline, Suzanne, Stella, Dequiedt, Franck, de Walque, Stéphane, Redel, Laetitia, Van Lint, Carine, Aunis, Dominique, Rohr, Olivier

“…Following entry and reverse transcription, the HIV‐1 genome is integrated into the host genome. In contrast to productively infected cells, latently infected…”
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CTIP2 is a negative regulator of P-TEFb by Cherrier, Thomas, Le Douce, Valentin, Eilebrecht, Sebastian, Riclet, Raphael, Marban, Céline, Dequiedt, Franck, Goumon, Yannick, Paillart, Jean-Christophe, Mericskay, Mathias, Parlakian, Ara, Bausero, Pedro, Abbas, Wasim, Herbein, Georges, Kurdistani, Siavash K., Grana, Xavier, Van Driessche, Benoit, Schwartz, Christian, Candolfi, Ermanno, Benecke, Arndt G., Van Lint, Carine, Rohr, Olivier

“…The positive transcription elongation factor b (P-TEFb) is involved in physiological and pathological events including inflammation, cancer, AIDS, and cardiac…”
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Enabling Routine MHC-II-Associated Peptide Proteomics for Risk Assessment of Drug-Induced Immunogenicity by Steiner, Guido, Marban-Doran, Céline, Langer, Jessica, Pimenova, Tatiana, Duran-Pacheco, Gonzalo, Sauter, Denise, Langenkamp, Anja, Solier, Corinne, Singer, Thomas, Bray-French, Katharine, Ducret, Axel

“…Major histocompatibility complex-II (MHC-II)-Associated Peptide Proteomics (MAPPs) is a mass spectrometry-based approach to identify and relatively quantitate…”
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Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties by Sela, Tatjana, Mansø, Mads, Siegel, Michel, Marban-Doran, Céline, Ducret, Axel, Niewöhner, Jens, Ravn, Jacob, Martin, Rainer E., Sommer, Annika, Lohmann, Sabine, Krippendorff, Ben-Fillippo, Ladefoged, Mette, Indlekofer, Annette, Quaiser, Tom, Bueddefeld, Florian, Koller, Erich, Mohamed, Mohamed Y., Oelschlaegel, Tobias, Gothelf, Kurt V., Hofer, Kerstin, Schumacher, Felix F.

“…Antisense-oligonucleotides (ASOs) are a promising drug modality for the treatment of neurological disorders, but the currently established route of…”
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Development and characterization of dendritic cell internalization and activation assays contributing to the immunogenicity risk evaluation of biotherapeutics by Siegel, Michel, Padamsey, Aman, Bolender, Anna-Lena, Hargreaves, Patrick, Fraidling, Johannes, Ducret, Axel, Hartman, Katharina, Looney, Cary M, Bertinetti-Lapatki, Cristina, Rohr, Olivier, Hickling, Timothy P, Kraft, Thomas E, Marban-Doran, Céline

“…Immunogenicity refers to the ability of a substance, such as a therapeutic drug, to elicit an immune response. While beneficial in vaccine development,…”
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Internalization of therapeutic antibodies into dendritic cells as a risk factor for immunogenicity by Siegel, Michel, Bolender, Anna-Lena, Ducret, Axel, Fraidling, Johannes, Hartman, Katharina, Looney, Cary M, Rohr, Olivier, Hickling, Timothy P, Kettenberger, Hubert, Lechmann, Martin, Marban-Doran, Céline, Kraft, Thomas E

“…Immunogenicity, the unwanted immune response triggered by therapeutic antibodies, poses significant challenges in biotherapeutic development. This response can…”
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D-Cateslytin, a new antimicrobial peptide with therapeutic potential by Zaet, Abdurraouf, Dartevelle, Pauline, Daouad, Fadoua, Ehlinger, Claire, Quilès, Fabienne, Francius, Grégory, Boehler, Christian, Bergthold, Camille, Frisch, Benoît, Prévost, Gilles, Lavalle, Philippe, Schneider, Francis, Haïkel, Youssef, Metz-Boutigue, Marie-Hélène, Marban, Céline

“…The rise of antimicrobial resistant microorganisms constitutes an increasingly serious threat to global public health. As a consequence, the efficacy of…”
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Genome-wide binding map of the HIV-1 Tat protein to the human genome by Marban, Céline, Su, Trent, Ferrari, Roberto, Li, Bing, Vatakis, Dimitrios, Pellegrini, Matteo, Zack, Jerome A, Rohr, Olivier, Kurdistani, Siavash K

“…The HIV-1 Trans-Activator of Transcription (Tat) protein binds to multiple host cellular factors and greatly enhances the level of transcription of the HIV…”
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HIV-1 regulation of latency in the monocyte-macrophage lineage and in CD4+ T lymphocytes by Redel, Laetitia, Le Douce, Valentin, Cherrier, Thomas, Marban, Céline, Janossy, Andrea, Aunis, Dominique, Van Lint, Carine, Rohr, Olivier, Schwartz, Christian

“…Review of molecular mechanisms of latency used by HIV‐1 to establish viral reservoirs within CD4 T cells and/or macrophages. The introduction in 1996 of the…”
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Expanding the MAPPs Assay to Accommodate MHC-II Pan Receptors for Improved Predictability of Potential T Cell Epitopes by Hartman, Katharina, Steiner, Guido, Siegel, Michel, Looney, Cary M, Hickling, Timothy P, Bray-French, Katharine, Springer, Sebastian, Marban-Doran, Céline, Ducret, Axel

“…A critical step in the immunogenicity cascade is attributed to human leukocyte antigen (HLA) II presentation triggering T cell immune responses. The liquid…”
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Validation of a Dendritic Cell and CD4+ T Cell Restimulation Assay Contributing to the Immunogenicity Risk Evaluation of Biotherapeutics by Siegel, Michel, Steiner, Guido, Franssen, Linnea C, Carratu, Francesca, Herron, James, Hartman, Katharina, Looney, Cary M, Ducret, Axel, Bray-French, Katharine, Rohr, Olivier, Hickling, Timothy P, Smith, Noel, Marban-Doran, Céline

“…Immunogenicity, defined as the ability to provoke an immune response, can be either wanted (i.e., vaccines) or unwanted. The latter refers to an immune…”
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Repression of Human T-lymphotropic virus type 1 Long Terminal Repeat sense transcription by Sp1 recruitment to novel Sp1 binding sites by Fauquenoy, Sylvain, Robette, Gwenaëlle, Kula, Anna, Vanhulle, Caroline, Bouchat, Sophie, Delacourt, Nadège, Rodari, Anthony, Marban, Céline, Schwartz, Christian, Burny, Arsène, Rohr, Olivier, Van Driessche, Benoit, Van Lint, Carine

“…Human T-lymphotropic Virus type 1 (HTLV-1) infection is characterized by viral latency in the majority of infected cells and by the absence of viremia. These…”
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Improving combination antiretroviral therapy by targeting HIV-1 gene transcription by Le Douce, Valentin, Ait-Amar, Amina, Forouzan Far, Faezeh, Fahmi, Faiza, Quiel, Jose, El Mekdad, Hala, Daouad, Fadoua, Marban, Céline, Rohr, Olivier, Schwartz, Christian

“…Combination Antiretroviral Therapy (cART) has not allowed the cure of HIV. The main obstacle to HIV eradication is the existence of quiescent reservoirs…”
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In Trauma Patients, the Occurrence of Early-Onset Nosocomial Infections is Associated With Increased Plasma Concentrations of Chromogranin A by Schneider, Francis, Marban, Céline, Ajob, Gharib, Helle, Sophie, Guillot, Max, Launoy, Anne, Maestraggi, Quentin, Scavello, Francesco, Rohr, Olivier, Metz-Boutigue, Marie-Hélène

“…ABSTRACTIn previously healthy persons suffering from acute illnesses, nosocomial infections (NIs) are frequent. Their prevalence suggests the existence of as…”
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Chromofungin, CgA47-66-derived peptide, produces basal cardiac effects and postconditioning cardioprotective action during ischemia/reperfusion injury by Filice, Elisabetta, Pasqua, Teresa, Quintieri, Anna Maria, Cantafio, Patrizia, Scavello, Francesco, Amodio, Nicola, Cerra, Maria Carmela, Marban, Céline, Schneider, Francis, Metz-Boutigue, Marie-Hélène, Angelone, Tommaso

“…[Display omitted] •The antifungal and antimicrobial chromofungin depresses rat cardiac performance.•Negative inotropism is mediated by the AKT/eNOS/cGMP/PKG…”
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Cateslytin, a chromogranin A derived peptide is active against Staphylococcus aureus and resistant to degradation by its proteases by Aslam, Rizwan, Marban, Céline, Corazzol, Christian, Jehl, François, Delalande, François, Van Dorsselaer, Alain, Prévost, Gilles, Haïkel, Youssef, Taddei, Corinne, Schneider, Francis, Metz-Boutigue, Marie-Hélène

“…Innate immunity involving antimicrobial peptides represents an integrated and highly effective system of molecular and cellular mechanisms that protects host…”
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HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1 by Le Douce, Valentin, Forouzanfar, Faezeh, Eilebrecht, Sebastian, Van Driessche, Benoit, Ait-Ammar, Amina, Verdikt, Roxane, Kurashige, Yoshihito, Marban, Céline, Gautier, Virginie, Candolfi, Ermanno, Benecke, Arndt G., Van Lint, Carine, Rohr, Olivier, Schwartz, Christian

“…Among many cellular transcriptional regulators, Bcl11b/CTIP2 and HGMA1 have been described to control the establishment and the persistence of HIV-1 latency in…”
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Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells by Rohr, Olivier, Marban, Céline, Aunis, Dominique, Schaeffer, Evelyne

“…Transcription is a crucial step for human immunodeficiency virus type 1 (HIV‐1) expression in all infected host cells, from T lymphocytes, thymocytes,…”
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A New Combination with D-Cateslytin to Eradicate Root Canal Pathogens by Ehlinger, Claire, Dartevelle, Pauline, Zaet, Abdurraouf, Kurashige, Yoshihito, Haïkel, Youssef, Metz-Boutigue, Marie-Hélène, Marban, Céline

“…The success of endodontic treatments depends on the elimination of intracanal pathogens. Since irrigation and instrumentation can only partially eliminate…”
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