Search Results - "Marazza, Alessandro"

Inhibition of the extracellular signal‐regulated kinase pathway reduces the inflammatory component in nucleus pulposus cells by Tekari, Adel, Marazza, Alessandro, Crump, Katherine, Bermudez‐Lekerika, Paola, Gantenbein, Benjamin

“…Intervertebral disc (IVD) degeneration is a spinal disorder that triggers an inflammatory response and subsequent development of spinal pseudoarthrosis. The…”
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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments by Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J., Molinari, Maurizio

“…LysoQuant is a deep learning approach to segmentation and classification of fluorescent images capturing cargo delivery within endolysosomes for clearance. It…”
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Endoplasmic Reticulum and Lysosomal Quality Control of Four Nonsense Mutants of Iduronate 2-Sulfatase Linked to Hunter's Syndrome by Marazza, Alessandro, Galli, Carmela, Fasana, Elisa, Sgrignani, Jacopo, Burda, Patricie, Fassi, Enrico M A, Baumgartner, Matthias, Cavalli, Andrea, Molinari, Maurizio

“…Hunter's syndrome (mucopolysaccharidosis type II) is a rare X-linked lysosomal storage disorder caused by mutations in the iduronate-2-sulfatase (IDS) gene…”
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A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex by Forrester, Alison, De Leonibus, Chiara, Grumati, Paolo, Fasana, Elisa, Piemontese, Marilina, Staiano, Leopoldo, Fregno, Ilaria, Raimondi, Andrea, Marazza, Alessandro, Bruno, Gemma, Iavazzo, Maria, Intartaglia, Daniela, Seczynska, Marta, van Anken, Eelco, Conte, Ivan, De Matteis, Maria Antonietta, Dikic, Ivan, Molinari, Maurizio, Settembre, Carmine

“…Autophagy is a cytosolic quality control process that recognizes substrates through receptor‐mediated mechanisms. Procollagens, the most abundant gene products…”
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Deep learning approach for quantification of organelles and misfolded polypeptides delivery within degradative compartments by Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J, Molinari, Maurizio

“…Endolysosomal compartments maintain cellular fitness by clearing from cells dysfunctional organelles and proteins. Modulation of their activity offers…”
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A selective ER ‐phagy exerts procollagen quality control via a Calnexin‐ FAM 134B complex by Forrester, Alison, De Leonibus, Chiara, Grumati, Paolo, Fasana, Elisa, Piemontese, Marilina, Staiano, Leopoldo, Fregno, Ilaria, Raimondi, Andrea, Marazza, Alessandro, Bruno, Gemma, Iavazzo, Maria, Intartaglia, Daniela, Seczynska, Marta, van Anken, Eelco, Conte, Ivan, De Matteis, Maria Antonietta, Dikic, Ivan, Molinari, Maurizio, Settembre, Carmine

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