Search Results - "Maranian, Mel J"

Posterior vitreous detachment in absentia by Maranian, Mel J., Snead, Martin P.

Get full text

Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping by Abraham, Jean E, Maranian, Mel J, Spiteri, Inmaculada, Russell, Roslin, Ingle, Susan, Luccarini, Craig, Earl, Helena M, Pharoah, Paul P D, Dunning, Alison M, Caldas, Carlos

“…The increasing trend for incorporation of biological sample collection within clinical trials requires sample collection procedures which are convenient and…”
Get full text

Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1 by Maranian, Mel J., Kar, Siddhartha, O’Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Canisius, Sander, Southey, Melissa C., Schmidt, Marjanka K., Hogervorst, Frans B., Muir, Kenneth, Ruebner, Matthias, Beckmann, Matthias W., Fletcher, Olivia, Bolla, Manjeet K., Wang, Qin, Sawyer, Elinor J., Tomlinson, Ian, Miller, Nicola, Burwinkel, Barbara, Yang, Rongxi, Surowy, Harald, Truong, Thérèse, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, González-Neira, Anna, Benitez, Javier, Brenner, Hermann, Dieffenbach, Aida Karina, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Nevanlinna, Heli, Muranen, Taru A., Blomqvist, Carl, Bogdanova, Natalia V., Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Tseng, Chiu-chen, Van Den Berg, David, Lambrechts, Diether, Zhao, Hui, Weltens, Caroline, van Limbergen, Erik, Flesch-Janys, Dieter, Rudolph, Anja, Radice, Paolo, Capra, Fabio, Couch, Fergus J., Vachon, Celine, Haiman, Christopher A., Le Marchand, Loic, Simard, Jacques, Labrèche, France, Dumont, Martine, Teo, Soo Hwang, Ikram, M. Kamran, Kristensen, Vessela, Shrubsole, Martha, Kauppila, Saila, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Tollenaar, Robert A.E.M., Van Asperen, Christi J., García-Closas, Montserrat, Figueroa, Jonine, Lissowska, Jolanta, Darabi, Hatef, Eriksson, Mikael, Martens, John W.M., Collée, J. Margriet, Shu, Xiao-Ou, Noh, Dong-Young, Hartman, Mikael, Hamann, Ute, Jaworska, Katarzyna, Durda, Katarzyna, Brennan, Paul, Olswold, Curtis, Slager, Susan, Yannoukakos, Drakoulis, Shen, Chen-Yang, Yu, Jyh-Cherng, Swerdlow, Anthony, Orr, Nick, Jones, Michael, Pita, Guillermo, Herrero, Daniel, Vincent, Daniel, Bacot, Francois, Ahmed, Shahana, Ponder, Bruce A.J., Chenevix-Trench, Georgia, Easton, Douglas F., French, Juliet D.

“…Genome-wide association studies (GWASs) have revealed SNP rs889312 on 5q11.2 to be associated with breast cancer risk in women of European ancestry. In an…”
Get full text

CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen by Abraham, Jean E, Maranian, Mel J, Driver, Kristy E, Platte, Radka, Kalmyrzaev, Bolot, Baynes, Caroline, Luccarini, Craig, Shah, Mitul, Ingle, Susan, Greenberg, David, Earl, Helena M, Dunning, Alison M, Pharoah, Paul D P, Caldas, Carlos

“…Tamoxifen is one of the most effective adjuvant breast cancer therapies available. Its metabolism involves the phase I enzyme, cytochrome P4502D6 (CYP2D6),…”
Get full text

CYP2D6 Gene Variants and Their Association with Breast Cancer Susceptibility by ABRAHAM, Jean E, MARANIAN, Mel J, CALDAS, Carlos, DRIVER, Kristy E, PLATTE, Radka, KALMYRZAEV, Bolot, BAYNES, Caroline, LUCCARINI, Craig, EARL, Helena M, DUNNING, Alison M, PHAROAH, Paul D. P

“…The gene encoding the phase I enzyme cytochrome P4502D6 (CYP2D6) has been previously investigated for its potential predictive role in the efficacy of breast…”
Get full text

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer by Lindstrom, Sara, Dennis, Joe, Maranian, Mel J, Brand, Judith S, Nordestgaard, Børge G, Flyger, Henrik, Rahman, Nazneen, Fletcher, Olivia, Nevanlinna, Heli, Muranen, Taru A, Aaltonen, Kirsimari, Ahsan, Habibul, John, Esther M, Gammon, Marilie D, Ursin, Giske, Schmidt, Daniel F, Gapstur, Susan M, Gaudet, Mia M, Diver, W Ryan, Schumacher, Fredrick, Hoover, Robert N, Lambrechts, Diether, Wildiers, Hans, van Limbergen, Erik, Broeks, Annegien, Cornelissen, Sten, Couch, Fergus J, Olson, Janet E, Hallberg, Emily, Meijers-Heijboer, Hanne, Ito, Hidemi, Iwata, Hiroji, Guénel, Pascal, Sanchez, Marie, Marme, Frederik, Surowy, Harald, Sohn, Christof, Van Den Berg, David, Benitez, Javier, Lu, Wei, Gao, Yu-Tang, Andrulis, Irene L, Knight, Julia A, Mulligan, Anna Marie, Sawyer, Elinor J, Tomlinson, Ian, Kerin, Michael J, Lindblom, Annika, Hollestelle, Antoinette, Collée, J Margriet, Blot, William, Signorello, Lisa B, Cai, Qiuyin, Hou, Ming-Feng, Kristensen, Vessela N, Milne, Roger L, McLean, Catriona, Peeters, Petra, Khaw, Kay-Tee, Palli, Domenico, Mortensen, Lotte Maxild, Dossus, Laure, Meindl, Alfons, Sutter, Christian, Yang, Rongxi, Muir, Kenneth, Siriwanarangsan, Pornthep, Miao, Hui, Chia, Kee Seng, Chan, Ching Wan, Fasching, Peter A, Beckmann, Matthias W, Haeberle, Lothar, Brenner, Hermann, Stegmaier, Christa, Ashworth, Alan, Schoemaker, Minouk J, Brinton, Louise, Zheng, Wei, Grip, Mervi, Brauch, Hiltrud, Radice, Paolo, Manoukian, Siranoush, Bernard, Loris, Dörk, Thilo, Hartikainen, Jaana M, Tollenaar, Robert A E M, Seynaeve, Caroline, Van Asperen, Christi J, Brennan, Paul, McKay, James, Neuhausen, Susan L, Baynes, Caroline, Ahmed, Shahana, Healey, Catherine S, Herrero, Daniel, Simard, Jacques, Chenevix-Trench, Georgia, Hall, Per, Easton, Douglas F

“…Doug Easton and colleagues report the results of a large-scale genome-wide association study of breast cancer. They discover 15 new susceptibility loci and…”
Get full text

Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers by Ghoussaini, Maya, Edwards, Stacey L., Meyer, Kerstin B., Ahmed, Shahana, Betts, Joshua A., Dicks, Ed, Beesley, Jonathan, Tyrer, Jonathan, Barnes, Daniel, Alonso, M. Rosario, Tessier, Daniel C., Luccarini, Craig, Baynes, Caroline, Bolla, Manjeet K., Wang, Qin, Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Verhoef, Senno, Cornelissen, Sten, Muir, Kenneth, Lophatananon, Artitaya, Siriwanarangsan, Pornthep, Loehberg, Christian R., Ekici, Arif B., dos Santos Silva, Isabel, Johnson, Nichola, Tomlinson, Ian, Truong, Thérèse, Menegaux, Florence, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Milne, Roger L., Benitez, Javier, Anton-Culver, Hoda, Brenner, Hermann, Stegmaier, Christa, Meindl, Alfons, Aittomäki, Kristiina, Matsuo, Keitaro, Iwata, Hiroji, Antonenkova, Natalia N., Dörk, Thilo, Mannermaa, Arto, Stram, Daniel O., Floris, Giuseppe, Chang-Claude, Jenny, Rudolph, Anja, Radice, Paolo, Bonanni, Bernardo, Couch, Fergus J., Pankratz, Vernon S., Giles, Graham G., Severi, Gianluca, Haiman, Christopher A., Schumacher, Fredrick, Simard, Jacques, Goldberg, Mark S., Dumont, Martine, Teo, Soo Hwang, Yip, Cheng Har, Vithana, Eranga Nishanthie, Kristensen, Vessela, Zheng, Wei, Pylkäs, Katri, Glendon, Gord, Seynaeve, Caroline, Figueroa, Jonine, Lissowska, Jolanta, Schoof, Nils, Martens, John W.M., Collée, J. Margriet, Tilanus-Linthorst, Madeleine, Hall, Per, Humphreys, Keith, Shu, Xiao-Ou, Gao, Yu-Tang, Cai, Hui, Cox, Angela, Balasubramanian, Sabapathy P., Blot, William, Pharoah, Paul D.P., Healey, Catherine S., Pooley, Karen A., Yoo, Keun-Young, Miao, Hui, Sim, Xueling, Jaworska-Bieniek, Katarzyna, Gaborieau, Valerie, Toland, Amanda E., Chen, Shou-Tung, Swerdlow, Anthony, Ashworth, Alan, Schoemaker, Minouk J., Nevanlinna, Heli, Chenevix-Trench, Georgia, Easton, Douglas F., Dunning, Alison M.

“…Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies identified three independent association signals for…”
Get full text

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer by Thompson, Deborah J, O'Mara, Tracy A, Glubb, Dylan M, Painter, Jodie N, Cheng, Timothy, Folkerd, Elizabeth, Doody, Deborah, Dennis, Joe, Webb, Penelope M, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Michailidou, Kyriaki, Tyrer, Jonathan P, Maranian, Mel J, Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Fasching, Peter A, Hein, Alexander, Beckmann, Matthias W, Ekici, Arif B, Dörk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Zhao, Hui, Depreeuw, Jeroen, Schrauwen, Stefanie, Amant, Frederic, Goode, Ellen L, Fridley, Brooke L, Dowdy, Sean C, Winham, Stacey J, Salvesen, Helga B, Trovik, Jone, Njolstad, Tormund S, Werner, Henrica M J, Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Carvajal-Carmona, Luis, Tham, Emma, Liu, Tao, Mints, Miriam, Scott, Rodney J, McEvoy, Mark, Attia, John, Holliday, Elizabeth G, Montgomery, Grant W, Martin, Nicholas G, Nyholt, Dale R, Henders, Anjali K, Hopper, John L, Traficante, Nadia, Ruebner, Matthias, Swerdlow, Anthony J, Burwinkel, Barbara, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Lambrechts, Diether, Chang-Claude, Jenny, Couch, Fergus J, Giles, Graham G, Kristensen, Vessela N, Cox, Angela, Bolla, Manjeet K, Wang, Qin, Bojesen, Stig E, Shah, Mitul, Luben, Robert, Khaw, Kay-Tee, Pharoah, Paul D P, Dunning, Alison M, Tomlinson, Ian, Dowsett, Mitch, Easton, Douglas F, Spurdle, Amanda B

“…Candidate gene studies have reported CYP19A1 variants to be associated with endometrial cancer and with estradiol (E2) concentrations. We analyzed 2937 single…”
Get full text