Search Results - "Maranhão, Andrea"
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Brazilian Publication Profiles: Where and How Brazilian authors publish
Published in Anais da Academia Brasileira de Ciências (01-01-2020)“…Abstract Publishing profiles can help institutions and financing agencies understand the different needs of knowledge areas and regions for development within…”
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Selection of Antibody Fragments for CAR-T Cell Therapy from Phage Display Libraries
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…CAR-T cell therapy emerged in the last years as a great promise to cancer treatment. Nowadays, there is a run to improve the breadth of its use, and thus, new…”
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Profiles not metrics: the case of Brazilian universities
Published in Anais da Academia Brasileira de Ciências (01-01-2021)“…Abstract Public universities, and science in general, in Brazil, are under attack from key persons of the government in interviews and articles published in…”
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Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum
Published in Toxicon (Oxford) (01-09-2009)“…Scorpion venom glands produce a large variety of bioactive peptides. This communication reports the identification of venom components obtained by sequencing…”
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Influence of carbon source on cell size and production of anti LDL (-) single-chain variable fragment by a recombinant Pichia pastoris strain
Published in Molecular biology reports (01-06-2019)“…The aim of this work was to study the effect of the carbon source (glycerol, sucrose, glucose or a sucrose/glucose mixture) on the production of the anti LDL…”
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Dendritic cells transfected with scFv from Mab 7.B12 mimicking original antigen gp43 induces protection against experimental Paracoccidioidomycosis
Published in PloS one (07-01-2011)“…Paracoccidioidomycosis (PCM), endemic in Latin America, is a progressive systemic mycosis caused by Paracoccidioides brasiliensis (P. brasiliensis), which…”
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Structural Changes in Stx1 Engineering Monoclonal Antibody Improves Its Functionality as Diagnostic Tool for a Rapid Latex Agglutination Test
Published in Antibodies (Basel) (01-02-2018)“…Stx1 toxin is one of the AB5 toxins of Shiga toxin-producing Escherichia coli (STEC) responsible for foodborne intoxication during outbreaks. The single-chain…”
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Isolation of Osteosarcoma-Associated Human Antibodies from a Combinatorial Fab Phage Display Library
Published in Journal of biomedicine & biotechnology (01-01-2009)“…Osteosarcoma, a highly malignant disease, is the most common primary bone tumor and is frequently found in children and adolescents. In order to isolate…”
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International collaboration in Brazilian science: financing and impact
Published in Scientometrics (2020)“…The study of international collaborations can help in understanding the benefits of such relationships and aid in developing national financing policies. In…”
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Characterization of hantaviruses circulating in Central Brazil
Published in Infection, genetics and evolution (01-03-2009)“…In 2004, an outbreak of HCPS in Brazil made hantaviruses a national threat to the rural and urban population. During this outbreak, 164 cases were reported,…”
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HSF-1, HIF-1and HSP90 expression on recombinant Pichia pastoris under fed-batch fermentation
Published in Brazilian journal of microbiology (01-06-2014)“…Pichia pastoris is a methylotrophic yeast used as an efficient expression system for heterologous protein production as compared to other expression systems…”
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Development and characterization of recombinant antibody fragments that recognize and neutralize in vitro Stx2 toxin from Shiga toxin-producing Escherichia coli
Published in PloS one (19-03-2015)“…Stx toxin is a member of the AB5 family of bacterial toxins: the active A subunit has N-glycosidase activity against 28S rRNA, resulting in inhibition of…”
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Response to heat stress for small ruminants: Physiological and genetic aspects
Published in Livestock science (01-09-2022)“…•Small ruminant´s response to heat stress is complex.•Traits involved include physical, physiological and metabolic.•Several gene pathways are up and down…”
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Novel humanized anti-CD3 antibodies induce a predominantly immunoregulatory profile in human peripheral blood mononuclear cells
Published in Immunology letters (15-08-2009)“…Abstract Strategies to minimize the immunogenicity and toxicity of murine anti-CD3 antibodies (e.g. OKT3) are of special interest for organ transplantation and…”
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Progress on Phage Display Technology: Tailoring Antibodies for Cancer Immunotherapy
Published in Viruses (01-09-2023)“…The search for innovative anti-cancer drugs remains a challenge. Over the past three decades, antibodies have emerged as an essential asset in successful…”
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In silico construction of a multiepitope Zika virus vaccine using immunoinformatics tools
Published in Scientific reports (07-01-2022)“…Zika virus (ZIKV) is an arbovirus from the Flaviviridae family and Flavivirus genus. Neurological events have been associated with ZIKV-infected individuals,…”
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New Anti-Flavivirus Fusion Loop Human Antibodies with Zika Virus-Neutralizing Potential
Published in International journal of molecular sciences (15-07-2022)“…Zika virus infections exhibit recurrent outbreaks and can be responsible for disease complications such as congenital Zika virus syndrome. Effective…”
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Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies
Published in BMC genomics (19-07-2019)“…Anti-CD3 immunotherapy was initially approved for clinical use for renal transplantation rejection prevention. Subsequently, new generations of anti-CD3…”
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A Germline-Encoded Structural Arginine Trap Underlies the Anti-DNA Reactivity of a Murine V Gene Segment
Published in International journal of molecular sciences (26-04-2021)“…Autoimmunity may have its origins of early repertoire selection in developmental B cells. Such a primary repertoire is probably shaped by selecting B cells…”
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Mucosal delivery of Lactococcus lactis carrying an anti-TNF scFv expression vector ameliorates experimental colitis in mice
Published in BMC biotechnology (25-06-2019)“…Anti-Tumor Necrosis Factor-alpha therapy has become clinically important for treating inflammatory bowel disease. However, the use of conventional…”
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