Search Results - "Maranchick, Nicole F"
-
1
Cerebrospinal fluid concentrations of fluoroquinolones and carbapenems in tuberculosis meningitis
Published in Frontiers in pharmacology (12-12-2022)“…Tuberculosis meningitis (TBM) is the most lethal form of TB. It is difficult to treat in part due to poor or uncertain drug penetration into the central…”
Get full text
Journal Article -
2
Impact of Beta-Lactam Target Attainment on Resistance Development in Patients with Gram-Negative Infections
Published in Antibiotics (Basel) (01-12-2023)“…The objective was to identify associations between beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) targets and Gram-negative bacteria resistance emergence…”
Get full text
Journal Article -
3
Role of therapeutic drug monitoring in the treatment of multi-drug resistant tuberculosis
Published in Journal of clinical tuberculosis and other mycobacterial diseases (01-08-2024)“…Tuberculosis (TB) is a leading cause of mortality worldwide, and resistance to anti-tuberculosis drugs is a challenge to effective treatment. Multi-drug…”
Get full text
Journal Article -
4
Early vigabatrin to augment GABAergic pathways in post-anoxic status epilepticus
Published in Epilepsy & behavior (01-11-2024)“…•Outcomes in post-anoxic status epilepticus are dismal despite advances in resuscitation.•Effective therapies targeting hyperexcitability from cardiac arrest…”
Get full text
Journal Article -
5
A Randomized Clinical Trial of Bayesian-Guided Beta-Lactam Infusion Strategy and Associated Bacterial Resistance and Clinical Outcomes in Patients With Severe Pneumonia
Published in Therapeutic drug monitoring (01-02-2024)“…Antimicrobial resistance is a growing health concern worldwide. The objective of this study was to evaluate the effect of beta-lactam infusion on the emergence…”
Get full text
Journal Article -
6
The effect of anti-tuberculosis drug pharmacokinetics on QTc prolongation
Published in International journal of antimicrobial agents (01-10-2023)“…•Among an observational cohort of patient being treated for drug-resistant tuberculosis, bedaquiline and delamanid based treatment regimens had a modest and…”
Get full text
Journal Article -
7
Abstract 257: VIGAB-STAT- A Phase IIa Feasibility Trial of Irreversible GABA-Transaminase Inhibition as Adjunct Treatment of Status Epilepticus After Cardiac Arrest
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Background: Effective therapeutic interventions for post-anoxic status epilepticus (PASE) are lacking. Vigabatrin (VGB) could be an attractive…”
Get full text
Journal Article