Search Results - "Marampon, Francesco"

Strategies for Bone Regeneration: From Graft to Tissue Engineering by Battafarano, Giulia, Rossi, Michela, De Martino, Viviana, Marampon, Francesco, Borro, Luca, Secinaro, Aurelio, Del Fattore, Andrea

“…Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very dynamic tissue subjected to continuous remodeling in order to preserve…”
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Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation by Marampon, Francesco, Ciccarelli, Carmela, Zani, Bianca Maria

“…ERK1 and ERK2 (ERKs), two extracellular regulated kinases (ERK1/2), are evolutionary-conserved and ubiquitous serine-threonine kinases involved in regulating…”
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Bone Control of Muscle Function by Battafarano, Giulia, Rossi, Michela, Marampon, Francesco, Minisola, Salvatore, Del Fattore, Andrea

“…Bone and muscle represent a single functional system and are tightly connected to each other. Indeed, diseases characterized by alterations of muscle…”
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New Insights on the Nuclear Functions and Targeting of FAK in Cancer by Pomella, Silvia, Cassandri, Matteo, Braghini, Maria Rita, Marampon, Francesco, Alisi, Anna, Rota, Rossella

“…Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase over-expressed and activated in both adult and pediatric cancers, where it plays important roles…”
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DNA Damage Response Gene Signature as Potential Treatment Markers for Oral Squamous Cell Carcinoma by Pomella, Silvia, Cassandri, Matteo, Melaiu, Ombretta, Marampon, Francesco, Gargari, Marco, Campanella, Vincenzo, Rota, Rossella, Barillari, Giovanni

“…Oral squamous cell carcinoma (OSCC) is a rapidly progressive cancer that often develops resistance against DNA damage inducers, such as radiotherapy and…”
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Cellular and Molecular Mediators of Bone Metastatic Lesions by Battafarano, Giulia, Rossi, Michela, Marampon, Francesco, Del Fattore, Andrea

“…Bone is the preferential site of metastasis for breast and prostate tumor. Cancer cells establish a tight relationship with the host tissue, secreting factors…”
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Caveolin-1 enhances metastasis formation in a human model of embryonal rhabdomyosarcoma through Erk signaling cooperation by Codenotti, Silvia, Faggi, Fiorella, Ronca, Roberto, Chiodelli, Paola, Grillo, Elisabetta, Guescini, Michele, Megiorni, Francesca, Marampon, Francesco, Fanzani, Alessandro

“…Rhabdomyosarcoma (RMS) is a pediatric soft tissue tumor classified in two major subtypes namely embryonal and alveolar, which have distinctive…”
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Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population by Ciccarelli, Carmela, Vulcano, Francesca, Milazzo, Luisa, Gravina, Giovanni Luca, Marampon, Francesco, Macioce, Giampiero, Giampaolo, Adele, Tombolini, Vincenzo, Di Paolo, Virginia, Hassan, Hamisa Jane, Zani, Bianca Maria

“…The identification of signaling pathways that affect the cancer stem-like phenotype may provide insights into therapeutic targets for combating embryonal…”
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MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells by Cassandri, Matteo, Pomella, Silvia, Rossetti, Alessandra, Petragnano, Francesco, Milazzo, Luisa, Vulcano, Francesca, Camero, Simona, Codenotti, Silvia, Cicchetti, Francesca, Maggio, Roberto, Festuccia, Claudio, Gravina, Giovanni Luca, Fanzani, Alessandro, Megiorni, Francesca, Catanoso, Marialuigia, Marchese, Cinzia, Tombolini, Vincenzo, Locatelli, Franco, Rota, Rossella, Marampon, Francesco

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. About 25% of RMS expresses fusion oncoproteins such as PAX3/PAX7-FOXO1…”
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Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation by Gravina, Giovanni L, Festuccia, Claudio, Marampon, Francesco, Popov, Vladimir M, Pestell, Richard G, Zani, Bianca M, Tombolini, Vincenzo

“…Epigenetic modifications play a key role in the patho-physiology of many tumors and the current use of agents targeting epigenetic changes has become a topic…”
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The Prostacyclin Analogue Iloprost Modulates CXCL10 in Systemic Sclerosis by Colasanti, Tania, Stefanantoni, Katia, Fantini, Cristina, Corinaldesi, Clarissa, Vasile, Massimiliano, Marampon, Francesco, Di Luigi, Luigi, Antinozzi, Cristina, Sgrò, Paolo, Lenzi, Andrea, Riccieri, Valeria, Crescioli, Clara

“…The prostacyclin analogue iloprost is used to treat vascular alterations and digital ulcers, the early derangements manifesting in systemic sclerosis (SSc), an…”
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Current status and perspectives of interventional clinical trials for brain metastases: analysis of ClinicalTrials.gov by Tini, Paolo, Marampon, Francesco, Giraffa, Martina, Bucelli, Samira, Niyazi, Maximilian, Belka, Claus, Minniti, Giuseppe

“…The management of brain metastases (BM), the major cause of cancer morbidity and mortality, is becoming an emerging area of interest. Surgery, whole brain…”
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Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma by Pomella, Silvia, Porrazzo, Antonella, Cassandri, Matteo, Camero, Simona, Codenotti, Silvia, Milazzo, Luisa, Vulcano, Francesca, Barillari, Giovanni, Cenci, Giovanni, Marchese, Cinzia, Fanzani, Alessandro, Megiorni, Francesca, Rota, Rossella, Marampon, Francesco

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and adolescence that includes FP-RMS, harboring the fusion oncoprotein PAX3/7-FOXO1…”
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Antitumour effects of SFX-01 molecule in combination with ionizing radiation in preclinical and in vivo models of rhabdomyosarcoma by Camero, Simona, Milazzo, Luisa, Vulcano, Francesca, Ceccarelli, Federica, Pontecorvi, Paola, Pedini, Francesca, Rossetti, Alessandra, Scialis, Elena Sofia, Gerini, Giulia, Cece, Fabrizio, Pomella, Silvia, Cassandri, Matteo, Porrazzo, Antonella, Romano, Enrico, Festuccia, Claudio, Gravina, Giovanni Luca, Ceccarelli, Simona, Rota, Rossella, Lotti, Lavinia Vittoria, Midulla, Fabio, Angeloni, Antonio, Marchese, Cinzia, Marampon, Francesco, Megiorni, Francesca

“…Despite a multimodal approach including surgery, chemo- and radiotherapy, the 5-year event-free survival rate for rhabdomyosarcoma (RMS), the most common soft…”
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The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma by Gravina, Giovanni Luca, Mancini, Andrea, Marampon, Francesco, Colapietro, Alessandro, Delle Monache, Simona, Sferra, Roberta, Vitale, Flora, Richardson, Peter J, Patient, Lee, Burbidge, Stephen, Festuccia, Claudio

“…Glioblastoma recurrence after treatment with the anti-vascular endothelial growth factor (VEGF) antibody bevacizumab is characterized by a highly infiltrative…”
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Muscle Damage in Systemic Sclerosis and CXCL10: The Potential Therapeutic Role of PDE5 Inhibition by Corinaldesi, Clarissa, Ross, Rebecca L, Abignano, Giuseppina, Antinozzi, Cristina, Marampon, Francesco, di Luigi, Luigi, Buch, Maya H, Riccieri, Valeria, Lenzi, Andrea, Crescioli, Clara, Del Galdo, Francesco

“…Skeletal muscle damage is a common clinical manifestation of systemic sclerosis (SSc). C-X-C chemokine ligand 10 (CXCL10) is involved in myopathy and…”
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Treatment of Solitary Painful Osseous Metastases with Radiotherapy, Cryoablation or Combined Therapy: Propensity Matching Analysis in 175 Patients by Di Staso, Mario, Gravina, Giovanni Luca, Zugaro, Luigi, Bonfili, Pierluigi, Gregori, Lorenzo, Franzese, Pietro, Marampon, Francesco, Vittorini, Francesca, Moro, Roberto, Tombolini, Vincenzo, Di Cesare, Ernesto, Masciocchi, Carlo

“…aim of this study was to identify outcomes in pain relief and quality of life in patients with a solitary painful osseous metastasis treated by radiotherapy,…”
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Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell lines by Marampon, Francesco, Di Nisio, Valentina, Pietrantoni, Ilaria, Petragnano, Francesco, Fasciani, Irene, Scicchitano, Bianca Maria, Ciccarelli, Carmela, Gravina, Giovanni Luca, Festuccia, Claudio, Del Fattore, Andrea, Tombolini, Mario, De Felice, Francesca, Musio, Daniela, Cecconi, Sandra, Tini, Paolo, Maddalo, Marta, Codenotti, Silvia, Fanzani, Alessandro, Polimeni, Antonella, Maggio, Roberto, Tombolini, Vincenzo

“…This study describes the in vitro and in vivo activity of PXD-101 (Belinostat), a novel hydroxamic acid-type pan-HDACs inhibitor characterized by a larger…”
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PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines by Camero, Simona, Ceccarelli, Simona, De Felice, Francesca, Marampon, Francesco, Mannarino, Olga, Camicia, Lucrezia, Vescarelli, Enrica, Pontecorvi, Paola, Pizer, Barry, Shukla, Rajeev, Schiavetti, Amalia, Mollace, Maria Giovanna, Pizzuti, Antonio, Tombolini, Vincenzo, Marchese, Cinzia, Megiorni, Francesca, Dominici, Carlo

“…Purpose PARP inhibitors (PARPi) are used in a wide range of human solid tumours but a limited evidence is reported in rhabdomyosarcoma (RMS), the most frequent…”
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Allosteric Modulators of G Protein-Coupled Dopamine and Serotonin Receptors: A New Class of Atypical Antipsychotics by Fasciani, Irene, Petragnano, Francesco, Aloisi, Gabriella, Marampon, Francesco, Carli, Marco, Scarselli, Marco, Maggio, Roberto, Rossi, Mario

“…Schizophrenia was first described by Emil Krapelin in the 19th century as one of the major mental illnesses causing disability worldwide. Since the…”
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