Search Results - "Marais, A"

Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease by Marais, A.David

“…Apolipoprotein E (apoE), a 34 kDa circulating glycoprotein of 299 amino acids, predominantly synthesised in the liver, associates with triglyceride-rich…”
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A new mechanism for atmospheric mercury redox chemistry: implications for the global mercury budget by Horowitz, Hannah M, Jacob, Daniel J, Zhang, Yanxu, Dibble, Theodore S, Slemr, Franz, Amos, Helen M, Schmidt, Johan A, Corbitt, Elizabeth S, Marais, Eloïse A, Sunderland, Elsie M

“…Mercury (Hg) is emitted to the atmosphere mainly as volatile elemental Hg0. Oxidation to water-soluble HgII plays a major role in Hg deposition to ecosystems…”
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Global mortality from outdoor fine particle pollution generated by fossil fuel combustion: Results from GEOS-Chem by Vohra, Karn, Vodonos, Alina, Schwartz, Joel, Marais, Eloise A., Sulprizio, Melissa P., Mickley, Loretta J.

“…The burning of fossil fuels – especially coal, petrol, and diesel – is a major source of airborne fine particulate matter (PM2.5), and a key contributor to the…”
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Apolipoprotein E and Atherosclerosis by Marais, A. D.

“…Purpose of Review The functions, genetic variations and impact of apolipoprotein E on lipoprotein metabolism in general are placed in the context of clinical…”
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Air Quality Impact of Diffuse and Inefficient Combustion Emissions in Africa (DICE-Africa) by Marais, Eloise A, Wiedinmyer, Christine

“…Anthropogenic pollution in Africa is dominated by diffuse and inefficient combustion sources, as electricity access is low and motorcycles and outdated cars…”
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A global anthropogenic emission inventory of atmospheric pollutants from sector- and fuel-specific sources (1970–2017): an application of the Community Emissions Data System (CEDS) by McDuffie, Erin E., Smith, Steven J., O'Rourke, Patrick, Tibrewal, Kushal, Venkataraman, Chandra, Marais, Eloise A., Zheng, Bo, Crippa, Monica, Brauer, Michael, Martin, Randall V.

“…Global anthropogenic emission inventories remain vital for understanding the sources of atmospheric pollution and the associated impacts on the environment,…”
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Global budget and radiative forcing of black carbon aerosol: Constraints from pole-to-pole (HIPPO) observations across the Pacific by Wang, Qiaoqiao, Jacob, Daniel J., Spackman, J. Ryan, Perring, Anne E., Schwarz, Joshua P., Moteki, Nobuhiro, Marais, Eloïse A., Ge, Cui, Wang, Jun, Barrett, Steven R. H.

“…We use a global chemical transport model (GEOS‐Chem) to interpret aircraft curtain observations of black carbon (BC) aerosol over the Pacific from 85°N to 67°S…”
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An evaluation of global organic aerosol schemes using airborne observations by Pai, Sidhant J, Heald, Colette L, Pierce, Jeffrey R, Farina, Salvatore C, Marais, Eloise A, Jimenez, Jose L, Campuzano-Jost, Pedro, Nault, Benjamin A, Middlebrook, Ann M, Coe, Hugh, Shilling, John E, Bahreini, Roya, Dingle, Justin H, Vu, Kennedy

“…Chemical transport models have historically struggled to accurately simulate the magnitude and variability of observed organic aerosol (OA), with previous…”
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On the rarity of dioecy in flowering plants by Käfer, Jos, Marais, Gabriel A. B., Pannell, John R.

“…Dioecy, the coexistence of separate male and female individuals in a population, is a rare but phylogenetically widespread sexual system in flowering plants…”
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Long‐term (2005–2014) trends in formaldehyde (HCHO) columns across North America as seen by the OMI satellite instrument: Evidence of changing emissions of volatile organic compounds by Zhu, Lei, Mickley, Loretta J., Jacob, Daniel J., Marais, Eloïse A., Sheng, Jianxiong, Hu, Lu, Abad, Gonzalo González, Chance, Kelly

“…Satellite observations of formaldehyde (HCHO) columns provide top‐down information on emissions of highly reactive volatile organic compounds (VOCs). We…”
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Sex differences in adult lifespan and aging rates of mortality across wild mammals by Lemaître, Jean-François, Ronget, Victor, Tidière, Morgane, Allainé, Dominique, Berger, Vérane, Cohas, Aurélie, Colchero, Fernando, Conde, Dalia A., Garratt, Michael, Liker, András, Marais, Gabriel A. B., Scheuerlein, Alexander, Székely, Tamás, Gaillard, Jean-Michel

“…In human populations, women consistently outlive men, which suggests profound biological foundations for sex differences in survival. Quantifying whether such…”
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Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study by Cuchel, Marina, Dr, Meagher, Emma A, MD, du Toit Theron, Hendrik, Prof, Blom, Dirk J, PhD, Marais, A David, Prof, Hegele, Robert A, Prof, Averna, Maurizio R, Prof, Sirtori, Cesare R, Prof, Shah, Prediman K, Prof, Gaudet, Daniel, MD, Stefanutti, Claudia, MD, Vigna, Giovanni B, MD, Du Plessis, Anna ME, MMed, Propert, Kathleen J, Prof, Sasiela, William J, PhD, Bloedon, LeAnne T, MS, Rader, Daniel J, Prof

“…Summary Background Patients with homozygous familial hypercholesterolaemia respond inadequately to existing drugs. We aimed to assess the efficacy and safety…”
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Familial dysbetalipoproteinemia: an underdiagnosed lipid disorder by Koopal, Charlotte, Marais, A David, Visseren, Frank L J

“…To review pathophysiological, epidemiological and clinical aspects of familial dysbetalipoproteinemia; a model disease for remnant metabolism and…”
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Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation by Parihar, Suraj P., Guler, Reto, Khutlang, Rethabile, Lang, Dirk M., Hurdayal, Ramona, Mhlanga, Musa M., Suzuki, Harukazu, Marais, A. David, Brombacher, Frank

“…Background. Statins are cholesterol-lowering drugs, targeting HMG-CoA reductase, thereby reducing the risk of coronary disorders and hypercholesterolemia…”
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Anthropogenic emissions of highly reactive volatile organic compounds in eastern Texas inferred from oversampling of satellite (OMI) measurements of HCHO columns by Zhu, Lei, Jacob, Daniel J, Mickley, Loretta J, Marais, Eloïse A, Cohan, Daniel S, Yoshida, Yasuko, Duncan, Bryan N, González Abad, Gonzalo, Chance, Kelly V

“…Satellite observations of formaldehyde (HCHO) columns provide top-down constraints on emissions of highly reactive volatile organic compounds (HRVOCs). This…”
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Survival in homozygous familial hypercholesterolaemia is determined by the on-treatment level of serum cholesterol by Thompson, Gilbert R, Blom, Dirk J, Marais, A David, Seed, Mary, Pilcher, Gillian J, Raal, Frederick J

“…Abstract Aims Homozygous familial hypercholesterolaemia (FH) is a rare inherited disorder characterized by extreme hypercholesterolaemia from birth,…”
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Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial by Raal, Frederick J, Prof, Santos, Raul D, MD, Blom, Dirk J, MD, Marais, A David, Prof, Charng, Min-Ji, MD, Cromwell, William C, MD, Lachmann, Robin H, MRCP, Gaudet, Daniel, MD, Tan, Ju L, MB BS, Chasan-Taber, Scott, PhD, Tribble, Diane L, PhD, Flaim, JoAnn D, PhD, Crooke, Stanley T, MD

“…Summary Background Homozygous familial hypercholesterolaemia is a rare genetic disorder in which both LDL-receptor alleles are defective, resulting in very…”
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Lomitapide and Mipomersen—Inhibiting Microsomal Triglyceride Transfer Protein (MTP) and apoB100 Synthesis by Blom, Dirk J., Raal, Frederick J., Santos, Raul D., Marais, A. David

“…Purpose of Review The goal of this review is to evaluate the role of inhibiting the synthesis of lipoproteins when there is no or little residual LDL-receptor…”
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Using satellite observations of tropospheric NO2 columns to infer long-term trends in US NOx emissions: the importance of accounting for the free tropospheric NO2 background by Silvern, Rachel F, Jacob, Daniel J, Mickley, Loretta J, Sulprizio, Melissa P, Travis, Katherine R, Marais, Eloise A, Cohen, Ronald C, Laughner, Joshua L, Choi, Sungyeon, Joiner, Joanna, Lamsal, Lok N

“…The National Emission Inventory (NEI) of the US Environmental Protection Agency (EPA) reports a steady decrease in US NOx emissions over the 2005–2017 period…”
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Glyoxal Yield from Isoprene Oxidation and Relation to Formaldehyde: Chemical Mechanism, Constraints from SENEX Aircraft Observations, and Interpretation of OMI Satellite Data by Miller, Christopher Chan, Jacob, Daniel J., Marais, Eloise A., Yu, Karen, Travis, Katherine R., Kim, Patrick S., Fisher, Jenny A., Zhu, Lei, Wolfe, Glenn M., Hanisco, Thomas F., Keutsch, Frank N., Kaiser, Jennifer, Min, Kyung-Eun, Brown, Steven S., Washenfelder, Rebecca A., Gonzalez Abad, Gonzalo, Chance, Kelly

“…Glyoxal (CHOCHO) is produced in the atmosphere by the oxidation of volatile organic compounds(VOCs). Like formaldehyde (HCHO), another VOC oxidation product,…”
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