Search Results - "Marabese, Ida"
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Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain
Published in Brain, behavior, and immunity (01-03-2020)“…•Vitamin D deficiency induces dysbiosis and alterations of endocannabinoidome members.•Vitamin D deficiency induces chronic pain and spinal…”
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Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain
Published in International journal of molecular sciences (11-05-2020)“…Neuropathic pain is a pathological condition induced by a lesion or disease affecting the somatosensory system, with symptoms like allodynia and hyperalgesia…”
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MED1/BDNF/TrkB pathway is involved in thalamic hemorrhage-induced pain and depression by regulating microglia
Published in Neurobiology of disease (01-03-2022)“…Central post-stroke pain (CPSP) and associated depression remain poorly understood and pharmacological treatments are unsatisfactory. Recently, microglia…”
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Nociception modulation by supraspinal group III metabotropic glutamate receptors
Published in Journal of neurochemistry (01-05-2017)“…The modulatory actions of glutamate, the main excitatory neurotransmitter in the central nervous system (CNS), are exerted through the activation of…”
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Vitamin D Deficiency Induces Chronic Pain and Microglial Phenotypic Changes in Mice
Published in International journal of molecular sciences (30-03-2021)“…The bioactive form of vitamin D, 1,25-dihydroxyvitamin D (1,25D3), exerts immunomodulatory actions resulting in neuroprotective effects potentially useful…”
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The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum
Published in Current neuropharmacology (01-01-2020)“…The dorsal striatum, apart from controlling voluntary movement, displays a recently demonstrated pain inhibition. It is connected to the descending pain…”
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Supraspinal metabotropic glutamate receptors: a target for pain relief and beyond
Published in The European journal of neuroscience (01-02-2014)“…Glutamate is the main excitatory neurotransmitter in the central nervous system, controlling the majority of synapses. Apart from neurodegenerative diseases,…”
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Metabotropic Glutamate Receptor 5 and 8 Modulate the Ameliorative Effect of Ultramicronized Palmitoylethanolamide on Cognitive Decline Associated with Neuropathic Pain
Published in International journal of molecular sciences (09-04-2019)“…This study investigated whether metabotropic glutamate receptor (mGluR) 5 and 8 are involved in the effect of ultramicronizedpalmitoylethanolamide (um-PEA) on…”
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Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain Injury
Published in Frontiers in pharmacology (16-04-2019)“…Neurological dysfunctions are the most impactful and persistent consequences of traumatic brain injury (TBI). Indeed, previous reports suggest that an…”
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Methods for Evaluating Sensory, Affective and Cognitive Disorders in Neuropathic Rodents
Published in Current neuropharmacology (01-01-2021)“…The animal models of neuropathic pain that faithfully reproduce the symptoms that occur in humans are a fundamental tool for understanding the mechanisms…”
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PEA-OXA restores cognitive impairments associated with vitamin D deficiency-dependent alterations of the gut microbiota
Published in Biomedicine & pharmacotherapy (01-06-2024)“…There is a growing evidence suggesting the association of vitamin D deficiency (VDD) and cognitive impairment. In this study we evaluated the possible…”
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Metabotropic Glutamate Receptor 7: From Synaptic Function to Therapeutic Implications
Published in Current neuropharmacology (01-07-2016)“…Metabotropic glutamate receptor 7 (mGluR7) is localized presynaptically at the active zone of neurotransmitter release. Unlike mGluR4 and mGluR8, which share…”
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Metabotropic glutamate receptor subtype 8 in the amygdala modulates thermal threshold, neurotransmitter release, and rostral ventromedial medulla cell activity in inflammatory pain
Published in The Journal of neuroscience (23-03-2011)“…The amygdala is a crucial area in controlling the threshold of pain and its emotional component. The present study has evaluated the effect of a metabotropic…”
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2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors
Published in Molecular brain (08-02-2021)“…Neuropathic pain (NP) remains an untreatable disease due to the complex pathophysiology that involves the whole pain neuraxis including the forebrain. Sensory…”
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Salvinorin A Reduces Mechanical Allodynia and Spinal Neuronal Hyperexcitability Induced by Peripheral Formalin Injection
Published in Molecular pain (23-08-2012)“…Background: Salvinorin A (SA), the main active component of Salvia Divinorum, is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to…”
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The Blockade of the Transient Receptor Potential Vanilloid Type 1 and Fatty Acid Amide Hydrolase Decreases Symptoms and Central Sequelae in the Medial Prefrontal Cortex of Neuropathic Rats
Published in Molecular pain (17-01-2011)“…Background: Neuropathic pain is a chronic disease resulting from dysfunction within the “pain matrix”. The basolateral amygdala (BLA) can modulate cortical…”
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Correction to: 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors
Published in Molecular brain (01-04-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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Changes in cannabinoid receptor subtype 1 activity and interaction with metabotropic glutamate subtype 5 receptors in the periaqueductal gray-rostral ventromedial medulla pathway in a rodent neuropathic pain model
Published in CNS & neurological disorders drug targets (01-03-2012)“…This study analyzed the effect of intra-ventrolateral periaqueductal grey (VL PAG) cannabinoid receptor (CB) stimulation on pain responses and rostral…”
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Interaction between vanilloid and glutamate receptors in the central modulation of nociception
Published in European journal of pharmacology (29-03-2002)“…This study investigates the effect of microinjections of capsaicin in the periaqueductal grey matter of rats on nociceptive behaviour and the possible…”
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EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat
Published in Molecular pain (24-10-2011)“…The aim of this study was to investigate the expression of prostaglandin EP1 receptor within the ventrolateral periaqueductal grey (VL PAG). The role of VL PAG…”
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