Search Results - "Mara, T."

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism by Sathyanarayan, Aishwarya, Mashek, Mara T., Mashek, Douglas G.

“…Hepatic lipid droplet (LD) catabolism is thought to occur via cytosolic lipases such as adipose triglyceride lipase (ATGL) or through autophagy of LDs, a…”
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ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling by Khan, Salmaan Ahmed, Sathyanarayan, Aishwarya, Mashek, Mara T, Ong, Kuok Teong, Wollaston-Hayden, Edith E, Mashek, Douglas G

“…Sirtuin 1 (SIRT1), an NAD(+)-dependent protein deacetylase, regulates a host of target proteins, including peroxisome proliferator-activated receptor (PPAR)-γ…”
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Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting[S] by Zhang, Enxiang, Cui, Wenqi, Lopresti, Michael, Mashek, Mara T., Najt, Charles P., Hu, Hongbo, Mashek, Douglas G.

“…Lipid droplets (LDs) are energy-storage organelles that are coated with hundreds of proteins, including members of the perilipin (PLIN) family. PLIN5 is highly…”
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Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1 by Najt, Charles P., Khan, Salmaan A., Heden, Timothy D., Witthuhn, Bruce A., Perez, Minervo, Heier, Jason L., Mead, Linnea E., Franklin, Mallory P., Karanja, Kenneth K., Graham, Mark J., Mashek, Mara T., Bernlohr, David A., Parker, Laurie, Chow, Lisa S., Mashek, Douglas G.

“…Lipid droplets (LDs) provide a reservoir for triacylglycerol storage and are a central hub for fatty acid trafficking and signaling in cells. Lipolysis…”
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Impacts of high‐intensity exercise on the metabolomics profile of human skeletal muscle tissue by Zagatto, Alessandro M., Bishop, David J., Antunes, Barbara Moura, Beck, Wladimir R., Malta, Elvis S., Poli, Rodrigo A.B., Cavaglieri, Claudia R., Chacon‐Mikahil, Mara Patrícia T., Castro, Alex

“…The study aimed to identify and quantify the metabolites profile and metabolic pathways in human muscle tissue engaged during exhaustive high‐intensity cycling…”
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Clinical Implications of Brief Device-Detected Atrial Tachyarrhythmias in a Cardiac Rhythm Management Device Population: Results from the Registry of Atrial Tachycardia and Atrial Fibrillation Episodes by Swiryn, Steven, Orlov, Michael V, Benditt, David G, DiMarco, John P, Lloyd-Jones, Donald M, Karst, Edward, Qu, Fujian, Slawsky, Mara T, Turkel, Melanie, Waldo, Albert L

“…BACKGROUND:The RATE Registry (Registry of Atrial Tachycardia and Atrial Fibrillation Episodes) is a prospective, outcomes-oriented registry designed to…”
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Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins by Zhang, Wenwei, Bu, So Young, Mashek, Mara T., O-Sullivan, InSug, Sibai, Zakaria, Khan, Salmaan A., Ilkayeva, Olga, Newgard, Christopher B., Mashek, Douglas G., Unterman, Terry G.

“…Metabolism is a highly integrated process that is coordinately regulated between tissues and within individual cells. FoxO proteins are major targets of…”
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Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning by Ong, Kuok Teong, Mashek, Mara T., Bu, So Young, Greenberg, Andrew S., Mashek, Douglas G.

“…Despite advances in our understanding of the ways in which nutrient oversupply and triacylglycerol (TAG) anabolism contribute to hepatic steatosis, little is…”
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Effect of wind direction on the response and capacity surface of a transmission tower by Mara, T.G., Hong, H.P.

“…•Nonlinear inelastic response of a transmission tower under different wind events.•Nonlinear static pushover analysis is used to obtain capacity…”
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Resistance Training Prevents Muscle Loss Induced by Caloric Restriction in Obese Elderly Individuals: A Systematic Review and Meta-Analysis by Sardeli, Amanda V, Komatsu, Tiemy R, Mori, Marcelo A, Gáspari, Arthur F, Chacon-Mikahil, Mara Patrícia T

“…It remains unclear as to what extent resistance training (RT) can attenuate muscle loss during caloric restriction (CR) interventions in humans. The objective…”
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Uncovering the mode of action of engineered T cells in patient cancer organoids by Dekkers, Johanna F., Alieva, Maria, Cleven, Astrid, Keramati, Farid, Wezenaar, Amber K. L., van Vliet, Esmée J., Puschhof, Jens, Brazda, Peter, Johanna, Inez, Meringa, Angelo D., Rebel, Heggert G., Buchholz, Maj-Britt, Barrera Román, Mario, Zeeman, Amber L., de Blank, Sam, Fasci, Domenico, Geurts, Maarten H., Cornel, Annelisa M., Driehuis, Else, Millen, Rosemary, Straetemans, Trudy, Nicolasen, Mara J. T., Aarts-Riemens, Tineke, Ariese, Hendrikus C. R., Johnson, Hannah R., van Ineveld, Ravian L., Karaiskaki, Froso, Kopper, Oded, Bar-Ephraim, Yotam E., Kretzschmar, Kai, Eggermont, Alexander M. M., Nierkens, Stefan, Wehrens, Ellen J., Stunnenberg, Henk G., Clevers, Hans, Kuball, Jürgen, Sebestyen, Zsolt, Rios, Anne C.

“…Extending the success of cellular immunotherapies against blood cancers to the realm of solid tumors will require improved in vitro models that reveal…”
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Suppression of Long Chain Acyl-CoA Synthetase 3 Decreases Hepatic de Novo Fatty Acid Synthesis through Decreased Transcriptional Activity by Bu, So Young, Mashek, Mara T., Mashek, Douglas G.

“…Long chain acyl-CoA synthetases (ACSL) and fatty acid transport proteins (FATP) activate fatty acids to acyl-CoAs in the initial step of fatty acid metabolism…”
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Cardiovascular telerehabilitation improves functional capacity, cardiorespiratory fitness and quality of life in older adults: A systematic review and meta-analysis by Nacarato, Diego, Sardeli, Amanda V, Mariano, Lilian O, Chacon-Mikahil, Mara Patrícia T

“…The aim was to identify whether cardiovascular telerehabilitation programs (CV-T-REHAB) can improve functional capacity, cardiorespiratory fitness and quality…”
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Differential Impact of Extended Criteria Donors After Brain Death or Circulatory Death in Adult Liver Transplantation by Pandya, Keval, Sastry, Vinay, Panlilio, Mara T., Yip, Terry C. F., Salimi, Shirin, West, Claire, Virtue, Susan, Wells, Mark, Crawford, Michael, Pulitano, Carlo, Strasser, Simone I., McCaughan, Geoffrey W., Majumdar, Avik, Liu, Ken

“…Using grafts from extended criteria donors (ECDs) and donation after circulatory death (DCD) donors is a strategy to address organ shortage in liver…”
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Synthesis and in Vivo Behavior of PVP/CMC/Agar Hydrogel Membranes Impregnated with Silver Nanoparticles for Wound Healing Applications by de Lima, Gabriel G, de Lima, Darlla W. F, de Oliveira, Maria J. A, Lugão, Ademar B, Alcântara, Mara T. S, Devine, Declan M, de Sá, Marcelo J. C

“…The field of wound healing has seen an increase in research activity in wound care and hydrogel-based dressings have been targeted as a solution for these…”
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Combined Training Reduces Subclinical Inflammation in Obese Middle-Age Men by BRUNELLI, DIEGO T, CHACON-MIKAHIL, MARA PATRÍCIA T, GÁSPARI, ARTHUR F, LOPES, WENDELL ARTHUR, BONGANHA, VALÉRIA, BONFANTE, IVAN LUIZ P, BELLOTTO, MARIA LUISA, LIBARDI, CLEITON AUGUSTO, CAVAGLIERI, CLÁUDIA REGINA

“…PURPOSEWe investigated the effects of 24 wk of combined training on proinflammatory and anti-inflammatory markers associated with obesity in obese middle-age…”
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Influence of Solid Area Distribution on the Drag of a Two-Dimensional Lattice Frame by Mara, T. G

“…AbstractMany wind design codes provide recommended values of the drag coefficient for generic lattice frame geometries based on the solidity ratio. The…”
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Random balance designs for the estimation of first order global sensitivity indices by Tarantola, S., Gatelli, D., Mara, T.A.

“…We present two methods for the estimation of main effects in global sensitivity analysis. The methods adopt Satterthwaite's application of random balance…”
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Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism by Ong, Kuok Teong, Mashek, Mara T., Davidson, Nicholas O., Mashek, Douglas G.

“…Adipose TG lipase (ATGL) catalyzes the rate-limiting step in TG hydrolysis in most tissues. We have shown that hepatic ATGL preferentially channels hydrolyzed…”
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Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation by Ong, Kuok Teong, Mashek, Mara T., Bu, So Young, Mashek, Douglas G.

“…Adipose triglyceride lipase (ATGL) is the predominant triacylglycerol (TAG) hydrolase in mammals; however, the tissue‐specific effects of ATGL outside of…”
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