Search Results - "Mara, Arlind B."
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CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
Published in The Journal of experimental medicine (05-06-2023)“…Dendritic cells (DCs) and monocytes capture, transport, and present antigen to cognate T cells in the draining lymph nodes (LNs) in a CCR7-dependent manner…”
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Rationally designed Mycoplasma gallisepticum vaccine using a recombinant subunit approach
Published in npj vaccines (28-09-2024)“…Mycoplasma gallisepticum (MG) is an avian respiratory pathogen causing significant global economic losses to the poultry industries. Current live-attenuated…”
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Vaccination with Mycoplasma pneumoniae membrane lipoproteins induces IL-17A driven neutrophilia that mediates Vaccine-Enhanced Disease
Published in npj vaccines (29-07-2022)“…Bacterial lipoproteins are an often-underappreciated class of microbe-associated molecular patterns with potent immunomodulatory activity. We previously…”
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Immunogenicity Threshold in Allogeneic Cells Impacts CTL Response to Nondominant Congenic Antigens
Published in The Journal of immunology (1950) (01-12-2023)“…Transplantation and cancer expose the immune system to neoantigens, including immunogenic (dominant and subdominant) and nonimmunogenic Ags with varying…”
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Coordinated chemokine expression defines macrophage subsets across tissues
Published in Nature immunology (01-06-2024)“…Lung-resident macrophages, which include alveolar macrophages and interstitial macrophages (IMs), exhibit a high degree of diversity, generally attributed to…”
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Transdermal microneedles for the programmable burst release of multiple vaccine payloads
Published in Nature biomedical engineering (01-09-2021)“…Repeated bolus injections are associated with higher costs and poor compliance and can hinder the implementation of global immunization campaigns. Here, we…”
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A GATA3 Targeting Nucleic Acid Nanocapsule for In Vivo Gene Regulation in Asthma
Published in ACS nano (27-07-2021)“…Allergic asthma is one of the leading chronic lung diseases of both children and adults worldwide, resulting in significant morbidity and mortality in affected…”
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Natural antibodies drive type 2 immunity in response to damage associated molecular patterns
Published in JCI insight (12-03-2024)“…Allergic Airway Disease (AAD) is an example of type 2 inflammation which leads to chronic airway eosinophilia controlled by CD4 Th2 cells. Inflammation is…”
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B cells oppose Mycoplasmapneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs
Published in npj vaccines (31-10-2022)“…Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and…”
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Lipid moieties of Mycoplasma pneumoniae lipoproteins are the causative factor of vaccine-enhanced disease
Published in npj vaccines (08-04-2020)“…Vaccine-enhanced disease (VED) occurs as a result of vaccination followed by infection with virulent Mycoplasma pneumoniae . To date VED has prevented…”
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11
B cells oppose M ycoplasma pneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs
Published in npj vaccines (01-12-2022)“…Abstract Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects…”
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12
B cells oppose Mycoplasma pneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs
Published in npj vaccines (31-10-2022)“…Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and…”
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Journal Article -
13
A CCL5 chemokine trail laid down by migratory dendritic cells directs CCR5 +antigen-presenting monocytes into draining lymph nodes
Published in The Journal of immunology (1950) (01-05-2023)“…Antigen presenting dendritic cells (DCs) and monocytes capture and transport antigens from barrier tissues for presentation to antigen-specific T cells in the…”
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14
Lipid moieties of Mycoplasma pneumoniae lipoproteins are the causative factor of vaccine-enhanced disease
Published in npj vaccines (08-04-2020)“…Vaccine-enhanced disease (VED) occurs as a result of vaccination followed by infection with virulent Mycoplasma pneumoniae. To date VED has prevented…”
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