Search Results - "Maříková, Jana"
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Reaction Outcome Critically Dependent on the Method of Workup: An Example from the Synthesis of 1‑Isoquinolones
Published in Journal of organic chemistry (18-06-2021)“…A striking dependence on the method of workup has been found for annulation of benzonitriles ArCN to N-methyl 2-toluamide (1), facilitated by n-BuLi (2…”
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2
Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease
Published in Phytochemistry (Oxford) (01-09-2019)“…Twenty-one known Amaryllidaceae alkaloids of various structural types and one undescribed alkaloid, named narcimatuline, have been isolated from fresh bulbs of…”
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3
Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase
Published in Journal of natural products (Washington, D.C.) (22-05-2020)“…A total of 20 derivatives (1–20) of the crinane-type alkaloid ambelline were synthesized. These semisynthetic derivatives were assessed for their potency to…”
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4
Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids
Published in Molecules (Basel, Switzerland) (26-02-2021)“…Two new minor Amaryllidaceae alkaloids were isolated from × cv. Ferrari and cv. Carlton. The chemical structures were identified by various spectroscopic (one-…”
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Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease
Published in Molecules (Basel, Switzerland) (03-04-2019)“…Twelve derivatives - of the β-crinane-type alkaloid haemanthamine were developed. All the semisynthetic derivatives were studied for their inhibitory potential…”
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6
Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies
Published in International journal of molecular sciences (01-08-2021)“…Alzheimer’s disease (AD) is a multifactorial neurodegenerative condition of the central nervous system (CNS) that is currently treated by cholinesterase…”
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Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease
Published in Phytochemistry (Oxford) (01-02-2022)“…One undescribed indole alkaloid together with twenty-two known compounds have been isolated from aerial parts of Vinca minor L. (Apocynaceae). The chemical…”
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Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents
Published in Molecules (Basel, Switzerland) (04-10-2021)“…The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious…”
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9
Radiocarbon dating of mortar charcoals from romanesque Southern Corridor, Prague Castle
Published in Journal of radioanalytical and nuclear chemistry (01-05-2023)“…The Southern Corridor of bishopric district was uncovered in early 1920s as the first Romanesque remains in the 3rd Courtyard of the Prague Castle. Based on…”
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Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase
Published in Biomolecules (Basel, Switzerland) (22-05-2020)“…Thirteen known ( - and ) and three previously undescribed Amaryllidaceae alkaloids of belladine structural type, named carltonine A-C ( - ), were isolated from…”
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11
A New Insight into the Stereoelectronic Control of the Pd 0 -Catalyzed Allylic Substitution: Application for the Synthesis of Multisubstituted Pyran-2-ones via an Unusual 1,3-Transposition
Published in Chemistry : a European journal (18-06-2019)“…Pyran-2-ones 3 undergo a novel Pd -catalyzed 1,3-rearrangement to afford isomers 6. The reaction proceeds via an η -Pd complex, the pyramidalization of which…”
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Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study
Published in Bioorganic & medicinal chemistry letters (01-11-2021)“…[Display omitted] Alzheimeŕs disease (AD) is the most common neurodegenerative disorder, characterized by neuronal loss and cognitive impairment. Currently,…”
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Alkaloids of Zephyranthes citrina (Amaryllidaceae) and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity
Published in Bioorganic chemistry (01-02-2021)“…[Display omitted] •Twenty-one Amaryllidaceae alkaloids isolated.•One new Amaryllidaceae alkaloid of narcikachnine-type isolated.•Absolute configuration of…”
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14
A New Insight into the Stereoelectronic Control of the Pd0‐Catalyzed Allylic Substitution: Application for the Synthesis of Multisubstituted Pyran‐2‐ones via an Unusual 1,3‐Transposition
Published in Chemistry : a European journal (18-06-2019)“…Pyran‐2‐ones 3 undergo a novel Pd0‐catalyzed 1,3‐rearrangement to afford isomers 6. The reaction proceeds via an η2‐Pd complex, the pyramidalization of which…”
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15
Amaryllidaceae Alkaloids of Different Structural Types from Narcissus L. cv. Professor Einstein and Their Cytotoxic Activity
Published in Plants (Basel) (22-01-2020)“…In this detailed phytochemical study of cv. Professor Einstein, we isolated 23 previously known Amaryllidaceae alkaloids ( - ) of several structural types and…”
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16
Quantifier elimination for o-minimal structures expanded by a valuational cut
Published in Annals of pure and applied logic (01-02-2023)“…Let R be an o-minimal expansion of a group in a language in which Th(R) eliminates quantifiers, and let C be a predicate for a valuational cut in R. We…”
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Measuring definable sets in o-minimal fields
Published in Israel journal of mathematics (01-09-2015)“…We introduce a non-real-valued measure on the definable sets contained in the finite part of a cartesian power of an o-minimal field R . The measure takes…”
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O-minimal residue fields of o-minimal fields
Published in Annals of pure and applied logic (01-04-2011)“…Let R be an o-minimal field with a proper convex subring V . We axiomatize the class of all structures ( R , V ) such that k ind , the corresponding residue…”
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19
O-minimal fields with standard part map
Published 01-01-2008“…Let R be an o-minimal field and V a proper convex subring of R with residue field k. Let kind be the expansion of the residue field by the standard parts of…”
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Dissertation -
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MODEL COMPLETENESS OF O-MINIMAL FIELDS WITH CONVEX VALUATIONS
Published in The Journal of symbolic logic (01-03-2015)“…We let R be an o-minimal expansion of a field. V a convex subring, and (R₀, V₀) an elementary substructure of (R, V). Our main result is that (R, V) considered…”
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