Search Results - "Marín Juez, Rubén"

Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish by Fukuda, Ryuichi, Marín‐Juez, Rubén, El‐Sammak, Hadil, Beisaw, Arica, Ramadass, Radhan, Kuenne, Carsten, Guenther, Stefan, Konzer, Anne, Bhagwat, Aditya M, Graumann, Johannes, Stainier, Didier YR

“…Cardiac metabolism plays a crucial role in producing sufficient energy to sustain cardiac function. However, the role of metabolism in different aspects of…”
Get full text

Fast revascularization of the injured area is essential to support zebrafish heart regeneration by Marín-Juez, Rubén, Marass, Michele, Gauvrit, Sebastien, Rossi, Andrea, Lai, Shih-Lei, Materna, Stefan C., Black, Brian L., Stainier, Didier Y. R.

“…Zebrafish have a remarkable capacity to regenerate their heart. Efficient replenishment of lost tissues requires the activation of different cell types…”
Get full text

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration by Lai, Shih-Lei, Marín-Juez, Rubén, Moura, Pedro Luís, Kuenne, Carsten, Lai, Jason Kuan Han, Tsedeke, Ayele Taddese, Guenther, Stefan, Looso, Mario, Stainier, Didier Yr

“…Zebrafish display a distinct ability to regenerate their heart following injury. However, this ability is not shared by another teleost, the medaka. In order…”
Get full text

Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation by Marín-Juez, Rubén, El-Sammak, Hadil, Helker, Christian S.M., Kamezaki, Aosa, Mullapuli, Sri Teja, Bibli, Sofia-Iris, Foglia, Matthew J., Fleming, Ingrid, Poss, Kenneth D., Stainier, Didier Y.R.

“…Defective coronary network function and insufficient blood supply are both cause and consequence of myocardial infarction. Efficient revascularization after…”
Get full text

Hif-1α regulates macrophage-endothelial interactions during blood vessel development in zebrafish by Gerri, Claudia, Marín-Juez, Rubén, Marass, Michele, Marks, Alora, Maischein, Hans-Martin, Stainier, Didier Y R.

“…Macrophages are known to interact with endothelial cells during developmental and pathological angiogenesis but the molecular mechanisms modulating these…”
Get full text

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development by Gauvrit, Sébastien, Villasenor, Alethia, Strilic, Boris, Kitchen, Philip, Collins, Michelle M., Marín-Juez, Rubén, Guenther, Stefan, Maischein, Hans-Martin, Fukuda, Nana, Canham, Maurice A., Brickman, Joshua M., Bogue, Clifford W., Jayaraman, Padma-Sheela, Stainier, Didier Y. R.

“…Formation of the lymphatic system requires the coordinated expression of several key regulators: vascular endothelial growth factor C (VEGFC), its receptor…”
Get full text

The stress responsive gene ankrd1a is dynamically regulated during skeletal muscle development and upregulated following cardiac injury in border zone cardiomyocytes in adult zebrafish by Boskovic, Srdjan, Marín Juez, Rubén, Stamenkovic, Nemanja, Radojkovic, Dragica, Stainier, Didier YR, Kojic, Snezana

“…•TgBAC(ankrd1a:EGFP) is expressed in the developing zebrafish slow muscle.•Exercise induces cardiac expression of TgBAC(ankrd1a:EGFP).•ankrd1a is upregulated…”
Get full text

Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration by Gancz, Dana, Raftrey, Brian C, Perlmoter, Gal, Marín-Juez, Rubén, Semo, Jonathan, Matsuoka, Ryota L, Karra, Ravi, Raviv, Hila, Moshe, Noga, Addadi, Yoseph, Golani, Ofra, Poss, Kenneth D, Red-Horse, Kristy, Stainier, Didier Yr, Yaniv, Karina

“…In recent years, there has been increasing interest in the role of lymphatics in organ repair and regeneration, due to their importance in immune surveillance…”
Get full text

GLUT2-Mediated Glucose Uptake and Availability Are Required for Embryonic Brain Development in Zebrafish by Marín-Juez, Rubén, Rovira, Mireia, Crespo, Diego, van der Vaart, Michiel, Spaink, Herman P, Planas, Josep V

“…Glucose transporter 2 (GLUT2; gene name SLC2A2) has a key role in the regulation of glucose dynamics in organs central to metabolism. Although GLUT2 has been…”
Get full text

Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection by Hu, Wanbin, Yang, Shuxin, Shimada, Yasuhito, Münch, Magnus, Marín-Juez, Rubén, Meijer, Annemarie H, Spaink, Herman P

“…The function of Toll-like receptor 2 (TLR2) in host defense against pathogens, especially Mycobacterium tuberculosis (Mtb) is poorly understood. To investigate…”
Get full text

Conditional mutagenesis by oligonucleotide-mediated integration of loxP sites in zebrafish by Burg, Leonard, Palmer, Nicholas, Kikhi, Khrievono, Miroshnik, Evgeniya S, Rueckert, Helen, Gaddy, Eleanor, MacPherson Cunningham, Carlee, Mattonet, Kenny, Lai, Shih-Lei, Marín-Juez, Rubén, Waring, Richard B, Stainier, Didier Y R, Balciunas, Darius

“…Many eukaryotic genes play essential roles in multiple biological processes in several different tissues. Conditional mutants are needed to analyze genes with…”
Get full text

Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise by Boskovic, Srdjan, Marín-Juez, Rubén, Jasnic, Jovana, Reischauer, Sven, El Sammak, Hadil, Kojic, Ana, Faulkner, Georgine, Radojkovic, Dragica, Stainier, Didier Y R, Kojic, Snezana

“…Muscle proteins with ankyrin repeats (MARPs) ANKRD1 and ANKRD2 are titin-associated proteins with a putative role as transcriptional co-regulators in striated…”
Get full text

Mechanisms regulating GLUT4 transcription in skeletal muscle cells are highly conserved across vertebrates by Marín-Juez, Rubén, Diaz, Mónica, Morata, Jordi, Planas, Josep V

“…The glucose transporter 4 (GLUT4) plays a key role in glucose uptake in insulin target tissues. This transporter has been extensively studied in many species…”
Get full text

Transcriptional and proteomic profiling of flatfish (Solea senegalensis) spermatogenesis by Forné, Ignasi, Castellana, Bárbara, Marín-Juez, Rubén, Cerdà, Joan, Abián, Joaquín, Planas, Josep V.

“…The Senegalese sole (Solea senegalensis) is a marine flatfish of high economic value and a target species for aquaculture. The efforts to reproduce this…”
Get full text

Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model by Collins, Michelle M., Ahlberg, Gustav, Hansen, Camilla Vestergaard, Guenther, Stefan, Marín-Juez, Rubén, Sokol, Anna M., El-Sammak, Hadil, Piesker, Janett, Hellsten, Ylva, Olesen, Morten S., Stainier, Didier Y. R., Lundegaard, Pia R.

“…Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The major AF susceptibility locus 4q25 establishes long-range interactions with the…”
Get full text

Cardiomyocyte heterogeneity during zebrafish development and regeneration by Tsedeke, Ayele Taddese, Allanki, Srinivas, Gentile, Alessandra, Jimenez-Amilburu, Vanesa, Rasouli, Seyed Javad, Guenther, Stefan, Lai, Shih-Lei, Stainier, Didier Y.R., Marín-Juez, Rubén

“…Contrary to adult mammals, zebrafish are able to regenerate their heart after cardiac injury. This regenerative response relies, in part, on the endogenous…”
Get full text

Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae by Ding, Yi, Raterink, Robert-Jan, Marín-Juez, Rubén, Veneman, Wouter J., Egbers, Koen, van den Eeden, Susan, Haks, Mariëlle C., Joosten, Simone A., Ottenhoff, Tom H. M., Harms, Amy C., Alia, A., Hankemeier, Thomas, Spaink, Herman P.

“…Tuberculosis is a highly infectious and potentially fatal disease accompanied by wasting symptoms, which cause severe metabolic changes in infected people. In…”
Get full text

Robotic injection of zebrafish embryos for high-throughput screening in disease models by Spaink, Herman P., Cui, Chao, Wiweger, Malgorzata I., Jansen, Hans J., Veneman, Wouter J., Marín-Juez, Rubén, de Sonneville, Jan, Ordas, Anita, Torraca, Vincenzo, van der Ent, Wietske, Leenders, William P., Meijer, Annemarie H., Snaar-Jagalska, B. Ewa, Dirks, Ron P.

“…The increasing use of zebrafish larvae for biomedical research applications is resulting in versatile models for a variety of human diseases. These models…”
Get full text

Correction: Mechanisms Regulating GLUT4 Transcription in Skeletal Muscle Cells Are Highly Conserved across Vertebrates by Marín-Juez, Rubén, Diaz, Mónica, Morata, Jordi, Planas, Josep V

“…[This corrects the article DOI: 10.1371/journal.pone.0080628.]…”
Get full text

Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish by Marín-Juez, Rubén, Jong-Raadsen, Susanne, Yang, Shuxin, Spaink, Herman P

“…Type 2 diabetes, obesity, and metabolic syndrome are pathologies where insulin resistance plays a central role, and that affect a large population worldwide…”
Get full text