Search Results - "María-Isabel Morosini"

Emergence and spread of antibiotic resistance following exposure to antibiotics by Cantón, Rafael, Morosini, María-Isabel

“…Abstract Within a susceptible wild-type population, a small fraction of cells, even <10−9, is not affected when challenged by an antimicrobial agent. This…”
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Murepavadin antimicrobial activity against and resistance development in cystic fibrosis Pseudomonas aeruginosa isolates by Díez-Aguilar, María, Hernández-García, Marta, Morosini, María-Isabel, Fluit, Ad, Tunney, Michael M, Huertas, Natalia, del Campo, Rosa, Obrecht, Daniel, Bernardini, Francesca, Ekkelenkamp, Miquel, Cantón, Rafael

“…Abstract Background Murepavadin, a novel peptidomimetic antibiotic, is being developed as an inhalation therapy for treatment of Pseudomonas aeruginosa…”
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Whole-genome sequencing reveals nosocomial Clostridioides difficile transmission and a previously unsuspected epidemic scenario by García-Fernández, Sergio, Frentrup, Martinique, Steglich, Matthias, Gonzaga, Aitor, Cobo, Marta, López-Fresneña, Nieves, Cobo, Javier, Morosini, María-Isabel, Cantón, Rafael, del Campo, Rosa, Nübel, Ulrich

“…To trace the routes and frequencies of transmission of Clostridioides difficile in a tertiary-care hospital in Madrid (Spain), we sequenced the genomes from…”
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Anti-biofilm activity of murepavadin against cystic fibrosis Pseudomonas aeruginosa isolates by Díez-Aguilar, María, Ekkelenkamp, Miquel, Morosini, María-Isabel, Huertas, Natalia, del Campo, Rosa, Zamora, Javier, Fluit, Ad C, Tunney, Michael M, Obrecht, Daniel, Bernardini, Francesca, Cantón, Rafael

“…Abstract Objectives To determine the activity of murepavadin in comparison with tobramycin, colistin and aztreonam, against cystic fibrosis (CF) Pseudomonas…”
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The Impact of Colistin Resistance on the Activation of Innate Immunity by Lipopolysaccharide Modification by Avendaño-Ortiz, José, Ponce-Alonso, Manuel, Llanos-González, Emilio, Barragán-Prada, Hugo, Barbero-Herranz, Raquel, Lozano-Rodríguez, Roberto, Márquez-Garrido, Francesc J, Hernández-Pérez, José María, Morosini, María-Isabel, Cantón, Rafael, Del Campo, Rosa, López-Collazo, Eduardo

“…Colistin resistance is acquired by different lipopolysaccharide (LPS) modifications. We proposed to evaluate the of effect colistin resistance acquisition on…”
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In vitro activity of ceftazidime, ceftaroline and aztreonam alone and in combination with avibactam against European Gram-negative and Gram-positive clinical isolates by Testa, Raymond, Cantón, Rafael, Giani, Tommaso, Morosini, María-Isabel, Nichols, Wright W, Seifert, Harald, Stefanik, Danuta, Rossolini, Gian Maria, Nordmann, Patrice

“…Highlights • The spectrum and activity of test compounds in combination with 4 mg/L avibactam was studied. • Avibactam restored the activities of ceftazidime,…”
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Reidentification of Streptococcus bovis Isolates Causing Bacteremia According to the New Taxonomy Criteria: Still an Issue? by Romero, Beatriz, Morosini, María-Isabel, Loza, Elena, Rodríguez-Baños, Mercedes, Navas, Enrique, Cantón, Rafael, Campo, Rosa del

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Antimicrobial susceptibility of non-fermenting Gram-negative pathogens isolated from cystic fibrosis patients by Díez-Aguilar, María, Ekkelenkamp, Miquel, Morosini, María-Isabel, Merino, Irene, de Dios Caballero, Juan, Jones, Mark, van Westreenen, Mireille, Tunney, Michael M., Cantón, Rafael, Fluit, Ad C.

“…•Non-fermenting Gram-negative bacteria other than P. aeruginosa are increasingly isolated from cystic fibrosis patients.•Trimethoprim/sulfamethoxazole was the…”
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Antibiotic Coresistance in Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae and In Vitro Activity of Tigecycline by MOROSINI, Maria-Isabel, GARCIA-CASTILLO, Maria, COQUE, Teresa M, VALVERDE, Aranzazu, NOVAIS, Angela, LOZA, Elena, BAQUERO, Fernando, CANTON, Rafael

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Evaluation of the eazyplex® SuperBug CRE system for rapid detection of carbapenemases and ESBLs in clinical Enterobacteriaceae isolates recovered at two Spanish hospitals by García-Fernández, Sergio, Morosini, María-Isabel, Marco, Francesc, Gijón, Desirèe, Vergara, Andrea, Vila, Jordi, Ruiz-Garbajosa, Patricia, Cantón, Rafael

“…To evaluate the performance of the eazyplex(®) SuperBug CRE system, a loop-mediated isothermal amplification (LAMP)-based system, for confirming the presence…”
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Performance of CHROMID® Colistin R agar, a new chromogenic medium for screening of colistin-resistant Enterobacterales by García-Fernández, Sergio, García-Castillo, María, Ruiz-Garbajosa, Patricia, Morosini, María-Isabel, Bala, Yohann, Zambardi, Gilles, Cantón, Rafael

“…Recent emergence of transferable plasmid-borne colistin resistance (mcr genes) raised fear for pan-resistance. We evaluated the performance of a new…”
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In Vitro Activity of Fosfomycin against a Collection of Clinical Pseudomonas aeruginosa Isolates from 16 Spanish Hospitals: Establishing the Validity of Standard Broth Microdilution as Susceptibility Testing Method by DIEZ-AGUILAR, Maria, MOROSINI, María-Isabel, DEL CAMPO, Rosa, GARCIA-CASTILLO, Maria, ZAMORA, Javier, CANTON, Rafael

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Detection of Carbapenemase Production in a Collection of Enterobacteriaceae with Characterized Resistance Mechanisms from Clinical and Environmental Origins by Use of Both Carba NP and Blue-Carba Tests by García-Fernández, Sergio, Morosini, María-Isabel, Gijón, Desirèe, Beatobe, Lorena, Ruiz-Garbajosa, Patricia, Domínguez, Lucas, Cantón, Rafael, Valverde, Aránzazu

“…Rapid-screening methods to confirm the presence of resistance mechanisms in multidrug-resistant bacteria are currently recommended. Carba NP and Blue-Carba…”
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MALDI-TOF MS improves routine identification of non-fermenting Gram negative isolates from cystic fibrosis patients by Fernández-Olmos, Ana, García-Castillo, María, Morosini, María-Isabel, Lamas, Adelaida, Máiz, Luis, Cantón, Rafael

“…Abstract Identification of non-fermenting Gram-negative bacteria (NFGNB) from cystic fibrosis (CF) patients is often limited. A collection of stored NFGNB…”
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Emergence and dissemination of colistin-resistant Klebsiella pneumoniae isolates expressing OXA-48 plus CTX-M-15 in patients not previously treated with colistin in a Spanish university hospital by Barragán-Prada, Hugo, Ruiz-Hueso, Paula, Tedim, Ana P., González-Candelas, Fernando, Galán, Juan Carlos, Cantón, Rafael, Morosini, María-Isabel

“…Dissemination of multidrug-resistant Klebsiella pneumoniae in the hospital environment represents a primary target of resistance containment and stewardship…”
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Gut eradication of VIM-1 producing ST9 Klebsiella oxytoca after fecal microbiota transplantation for diarrhea caused by a Clostridium difficile hypervirulent R027 strain by García-Fernández, Sergio, Morosini, María-Isabel, Cobo, Marta, Foruny, José Ramón, López-Sanromán, Antonio, Cobo, Javier, Romero, José, Cantón, Rafael, del Campo, Rosa

“…Abstract We report the fecal carriage eradication of a VIM-1-producing ST9 Klebsiella oxytoca strain in a pluripathological 84-year-old woman after fecal…”
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Early OXA-48-Producing Enterobacterales Isolates Recovered in a Spanish Hospital Reveal a Complex Introduction Dominated by Sequence Type 11 (ST11) and ST405 Klebsiella pneumoniae Clones by Gijón, Desirèe, Tedim, Ana P, Valverde, Aránzazu, Rodríguez, Irene, Morosini, María-Isabel, Coque, Teresa M, Manrique, Marina, Pareja, Eduardo, Tobes, Raquel, Ruiz-Garbajosa, Patricia, Cantón, Rafael

“…Carbapenemase-producing (CPE) have become an important public health concern. In our hospital, VIM enzymes were first detected in 2005, carbapenemase (KPC)…”
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Molecular analysis of yogurt containing Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus in human intestinal microbiota by García-Albiach, Raimundo, José, María, de Felipe, Pozuelo, Angulo, Santiago, Morosini, María-Isabel, Bravo, Daniel, Baquero, Fernando, del Campo, Rosa

“…Yogurt has traditionally been considered a probiotic-carrier food with health-promoting effects. Despite the universal assumption of this assertion, several…”
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Emergence of cfr-Mediated Linezolid Resistance in a Methicillin-Resistant Staphylococcus aureus Epidemic Clone Isolated from Patients with Cystic Fibrosis by de Dios Caballero, Juan, Pastor, María Dolores, Vindel, Ana, Máiz, Luis, Yagüe, Genoveva, Salvador, Carme, Cobo, Marta, Morosini, María-Isabel, del Campo, Rosa, Cantón, Rafael

“…Resistance to linezolid (LZD) in methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients with cystic fibrosis (CF) is due mainly to ribosomal…”
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Performance of EUCAST and CLSI approaches for co-amoxiclav susceptibility testing conditions for clinical categorization of a collection of Escherichia coli isolates with characterized resistance phenotypes by Díez-Aguilar, María, Morosini, María-Isabel, López-Cerero, Lorena, Pascual, Álvaro, Calvo, Jorge, Martínez-Martínez, Luis, Marco, Francesc, Vila, Jordi, Ortega, Adriana, Oteo, Jesús, Cantón, Rafael

“…There are different methodological recommendations for in vitro testing of the co-amoxiclav combination. Performance of co-amoxiclav MIC testing for…”
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