Search Results - "María José Pomares"
-
1
Signaling During Epicardium and Coronary Vessel Development
Published in Circulation research (09-12-2011)“…The epicardium, the tissue layer covering the cardiac muscle (myocardium), develops from the proepicardium, a mass of coelomic progenitors located at the…”
Get full text
Journal Article -
2
Differential Notch Signaling in the Epicardium Is Required for Cardiac Inflow Development and Coronary Vessel Morphogenesis
Published in Circulation research (01-04-2011)“…RATIONALE:The proepicardium is a transient structure comprising epicardial progenitor cells located at the posterior limit of the embryonic cardiac inflow. A…”
Get full text
Journal Article -
3
Training biochemistry students in experimental developmental biology: Induction of cardia bifida formation in the chick embryo
Published in Biochemistry and molecular biology education (01-09-2021)“…A high variety of experimental model organisms have been used in developmental biology practical lectures. The work with developing embryos is crucial to make…”
Get full text
Journal Article -
4
Congenital coronary artery anomalies: a bridge from embryology to anatomy and pathophysiology--a position statement of the development, anatomy, and pathology ESC Working Group
Published in Cardiovascular research (01-02-2016)“…Congenital coronary artery anomalies are of major significance in clinical cardiology and cardiac surgery due to their association with myocardial ischaemia…”
Get full text
Journal Article -
5
Cellular identities in an unusual presentation of cyclopia in a chick embryo
Published in Journal of experimental zoology. Part B, Molecular and developmental evolution (01-09-2019)“…Cyclopia is a congenital anomaly characterized by the presence of a single or partially divided eye in a single orbit at the body midline. This condition is…”
Get full text
Journal Article -
6
In Vivo and In Vitro Cartilage Differentiation from Embryonic Epicardial Progenitor Cells
Published in International journal of molecular sciences (25-03-2022)“…The presence of cartilage tissue in the embryonic and adult hearts of different vertebrate species is a well-recorded fact. However, while the embryonic neural…”
Get full text
Journal Article -
7
Early embryonic vascular patterning by matrix-mediated paracrine signalling: a mathematical model study
Published in PloS one (19-09-2011)“…During embryonic vasculogenesis, endothelial precursor cells of mesodermal origin known as angioblasts assemble into a characteristic network pattern. Although…”
Get full text
Journal Article -
8
Coronary stem development in wild‐type and Tbx1 null mouse hearts
Published in Developmental dynamics (01-04-2016)“…Background: Coronary artery (CA) stems connect the ventricular coronary tree with the aorta. Defects in proximal CA patterning are a cause of sudden cardiac…”
Get full text
Journal Article -
9
Cell-based therapies for the treatment of myocardial infarction: lessons from cardiac regeneration and repair mechanisms in non-human vertebrates
Published in Heart failure reviews (2019)“…Ischemic cardiomyopathy is the cardiovascular condition with the highest impact on the Western population. In mammals (humans included), prolonged ischemia in…”
Get full text
Journal Article -
10
Origin of coronary endothelial cells from epicardial mesothelium in avian embryos
Published in The International journal of developmental biology (01-12-2002)“…It has been established that coronary vessels develop through self-assembly of mesenchymal vascular progenitors in the subepicardium. Mesenchymal precursors of…”
Get full text
Journal Article -
11
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
Published in Genes & development (01-01-2004)“…Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and tumor metastasis. The Notch intercellular signaling pathway regulates cell…”
Get full text
Journal Article -
12
Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity
Published in Cell death & disease (14-03-2018)“…During mammalian heart development, restricted myocardial Bmp2 expression is a key patterning signal for atrioventricular canal specification and the…”
Get full text
Journal Article -
13
Fsp1 cardiac embryonic expression delineates atrioventricular endocardial cushion, coronary venous and lymphatic valve development
Published in Journal of anatomy (01-02-2021)“…Fsp1 (a.k.a S100A4 or Metastatin) is an intracellular and secreted protein widely regarded as a fibroblast marker. Recent studies have nonetheless shown that…”
Get full text
Journal Article -
14
Notch Signaling Is Essential for Ventricular Chamber Development
Published in Developmental cell (01-03-2007)“…Ventricular chamber morphogenesis, first manifested by trabeculae formation, is crucial for cardiac function and embryonic viability and depends on cellular…”
Get full text
Journal Article -
15
The Origin of the Subepicardial Mesenchyme in the Avian Embryo: An Immunohistochemical and Quail–Chick Chimera Study
Published in Developmental biology (01-08-1998)“…It has been proposed that the subepicardial mesenchymal cells (SEMC) originate from the primitive epicardium and also from migration of extracardiac mesenchyme…”
Get full text
Journal Article -
16
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation
Published in The Journal of clinical investigation (01-10-2010)“…Cardiac valve formation is crucial for embryonic and adult heart function. Valve malformations constitute the most common congenital cardiac defect, but little…”
Get full text
Journal Article -
17
URINARY INFECTIONS IN SPECIAL SITUATIONS: KIDNEY TRANSPLANT AND DIALYSIS
Published in Revista de la Sociedad Argentina de Diabetes (01-06-2019)“…Patients on hemodialysis often have more urinary tract infections (UTIs) due to immunosuppression, lack of germ removal, presence of lithiasis, neurogenic…”
Get full text
Journal Article -
18
MANAGEMENT OF ALBUMINURIA. MOMENT OF NEPHROLOGY REFERRAL
Published in Revista de la Sociedad Argentina de Diabetes (01-08-2018)“…In the last years new observations arise that allowed to unders- tand that the clinical course of kidney disease caused by diabetes might be different from the…”
Get full text
Journal Article -
19
Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2
Published in Development (Cambridge) (15-03-2011)“…Epicardial-derived signals are key regulators of cardiac embryonic development. An important part of these signals is known to relate to a retinoic acid (RA)…”
Get full text
Journal Article -
20
Bmi1-Progenitor Cell Ablation Impairs the Angiogenic Response to Myocardial Infarction
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2018)“…OBJECTIVE—Cardiac progenitor cells reside in the heart in adulthood, although their physiological relevance remains unknown. Here, we demonstrate that after…”
Get full text
Journal Article