Search Results - "María Cristina Motta"
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Glycosomal bromodomain factor 1 from Trypanosoma cruzi enhances trypomastigote cell infection and intracellular amastigote growth
Published in Biochemical journal (01-01-2016)“…Acetylation is a ubiquitous protein modification present in prokaryotic and eukaryotic cells that participates in the regulation of many cellular processes…”
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Trypanosoma cruzi bromodomain factor 3 binds acetylated α-tubulin and concentrates in the flagellum during metacyclogenesis
Published in Eukaryotic cell (01-06-2014)“…Bromodomains are highly conserved acetyl-lysine binding domains found mainly in proteins associated with chromatin and nuclear acetyltransferases. The…”
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Importance of Angomonas deanei KAP4 for kDNA arrangement, cell division and maintenance of the host-bacterium relationship
Published in Scientific reports (28-04-2021)“…Angomonas deanei coevolves in a mutualistic relationship with a symbiotic bacterium that divides in synchronicity with other host cell structures…”
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Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity
Published in Scientific reports (17-01-2019)“…Kinetoplastid parasites, included Trypanosoma cruzi , the causal agent of Chagas disease, present a unique genome organization and gene expression. Although…”
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Revisiting the Trypanosoma cruzi metacyclogenesis: morphological and ultrastructural analyses during cell differentiation
Published in Parasites & vectors (06-02-2018)“…Trypanosoma cruzi uses several strategies to survive in different hosts. A key step in the life-cycle of this parasite is metacyclogenesis, which involves…”
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High‐throughput screening for distinguishing nitrilases from nitrile hydratases in Aspergillus and application of a Box–Behnken design for the optimization of nitrilase
Published in Biotechnology and applied biochemistry (01-10-2022)“…Nitrilases and nitrile hydratases/amidases hydrolyze nitriles into carboxylic acids and/or amides, which are used in industrial chemical processes. In the…”
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Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers
Published in BMC evolutionary biology (09-09-2013)“…Trypanosomatids of the genera Angomonas and Strigomonas live in a mutualistic association characterized by extensive metabolic cooperation with obligate…”
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Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci
Published in Epigenetics & chromatin (01-06-2022)“…Genomic organization and gene expression regulation in trypanosomes are remarkable because protein-coding genes are organized into codirectional gene clusters…”
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The effect of the biflavonoid 2″,3″-dihydroochnaflavone on Trypanosoma cruzi Y strain
Published in Parasitology international (01-12-2020)“…Trypanosoma cruzi is the causative agent of Chagas disease which affects 8 million people in Latin America. The parasite possesses high capacity to evade host…”
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Elastin increases biofilm and extracellular matrix production of Aspergillus fumigatus
Published in Brazilian journal of microbiology (01-07-2018)“…Aspergillus fumigatus is an opportunistic saprobe fungus that accounts for 90% of cases of pulmonary aspergillosis in immunosuppressed patients and is known…”
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Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi
Published in Frontiers in cellular and infection microbiology (31-01-2020)“…Glycosomes are peroxisome-related organelles that have been identified in kinetoplastids and diplonemids. The hallmark of glycosomes is their harboring of the…”
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Endosymbiosis in trypanosomatid protozoa: the bacterium division is controlled during the host cell cycle
Published in Frontiers in microbiology (02-06-2015)“…Mutualism is defined as a beneficial relationship for the associated partners and usually assumes that the symbiont number is controlled. Some trypanosomatid…”
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Species diversity of fusarioid genera associated with sweet potato in Brazil, including the description of a new species
Published in Plant pathology (01-05-2024)“…Abstract The sweet potato is of great socioeconomic importance in Brazil and throughout the world. Among the fungal pathogens associated with root diseases of…”
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Chromosomal assembly of the nuclear genome of the endosymbiont-bearing trypanosomatid Angomonas deanei
Published in G3 : genes - genomes - genetics (01-01-2021)“…Angomonas deanei is an endosymbiont-bearing trypanosomatid with several highly fragmented genome assemblies and unknown chromosome number. We present an…”
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Alpha-Tubulin Acetylation in Trypanosoma cruzi : A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression
Published in Frontiers in cellular and infection microbiology (11-03-2021)“…Trypanosomatids have a cytoskeleton arrangement that is simpler than what is found in most eukaryotic cells. However, it is precisely organized and constituted…”
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Biosynthesis of vitamins and cofactors in bacterium-harbouring trypanosomatids depends on the symbiotic association as revealed by genomic analyses
Published in PloS one (19-11-2013)“…Some non-pathogenic trypanosomatids maintain a mutualistic relationship with a betaproteobacterium of the Alcaligenaceae family. Intensive nutritional…”
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Expanded repertoire of kinetoplast associated proteins and unique mitochondrial DNA arrangement of symbiont-bearing trypanosomatids
Published in PloS one (13-11-2017)“…In trypanosomatids, the kinetoplast is the portion of the single mitochondrion that is connected to the basal body and contains the kDNA, a network composed by…”
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Brazilian tropical dry forest (Caatinga) in the spotlight: an overview of species of Aspergillus, Penicillium and Talaromyces (Eurotiales) and the description of P. vascosobrinhous sp. nov
Published in Acta Botânica Brasílica (01-06-2020)“…ABSTRACT A literature-based checklist of species of Aspergillus, Penicillium, and Talaromyces recorded in the Brazilian tropical dry forest (Caatinga), the…”
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The Symbiotic Bacterium Fuels the Energy Metabolism of the Host Trypanosomatid Strigomonas culicis
Published in Protist (01-04-2017)“…The mutualistic relationship between trypanosomatids and their respective endosymbiotic bacteria represents an excellent model for studying metabolic…”
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