Search Results - "Mapelli, Sarah"

Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions by Silva‐Gomes, Rita, Mapelli, Sarah N., Boutet, Marie‐Astrid, Mattiola, Irene, Sironi, Marina, Grizzi, Fabio, Colombo, Federico, Supino, Domenico, Carnevale, Silvia, Pasqualini, Fabio, Stravalaci, Matteo, Porte, Rémi, Gianatti, Andrea, Pitzalis, Constantino, Locati, Massimo, Oliveira, Maria José, Bottazzi, Barbara, Mantovani, Alberto

“…The MS4A gene family encodes 18 tetraspanin‐like proteins, most of which with unknown function. MS4A1 (CD20), MS4A2 (FcεRIβ), MS4A3 (HTm4), and MS4A4A play…”
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Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules by Stravalaci, Matteo, Pagani, Isabel, Paraboschi, Elvezia Maria, Pedotti, Mattia, Doni, Andrea, Scavello, Francesco, Mapelli, Sarah N., Sironi, Marina, Perucchini, Chiara, Varani, Luca, Matkovic, Milos, Cavalli, Andrea, Cesana, Daniela, Gallina, Pierangela, Pedemonte, Nicoletta, Capurro, Valeria, Clementi, Nicola, Mancini, Nicasio, Invernizzi, Pietro, Bayarri-Olmos, Rafael, Garred, Peter, Rappuoli, Rino, Duga, Stefano, Bottazzi, Barbara, Uguccioni, Mariagrazia, Asselta, Rosanna, Vicenzi, Elisa, Mantovani, Alberto, Garlanda, Cecilia

“…The humoral arm of innate immunity includes diverse molecules with antibody-like functions, some of which serve as disease severity biomarkers in coronavirus…”
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Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer by Civenni, Gianluca, Bosotti, Roberto, Timpanaro, Andrea, Vàzquez, Ramiro, Merulla, Jessica, Pandit, Shusil, Rossi, Simona, Albino, Domenico, Allegrini, Sara, Mitra, Abhishek, Mapelli, Sarah N., Vierling, Luca, Giurdanella, Martina, Marchetti, Martina, Paganoni, Alyssa, Rinaldi, Andrea, Losa, Marco, Mira-Catò, Enrica, D'Antuono, Rocco, Morone, Diego, Rezai, Keyvan, D'Ambrosio, Gioacchino, Ouafik, L’Houcine, Mackenzie, Sarah, Riveiro, Maria E., Cvitkovic, Esteban, Carbone, Giuseppina M., Catapano, Carlo V.

“…Cancer stem cells (CSCs) contribute to disease progression and treatment failure in human cancers. The balance among self-renewal, differentiation, and…”
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Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19 by Brunetta, Enrico, Folci, Marco, Bottazzi, Barbara, De Santis, Maria, Gritti, Giuseppe, Protti, Alessandro, Mapelli, Sarah N., Bonovas, Stefanos, Piovani, Daniele, Leone, Roberto, My, Ilaria, Zanon, Veronica, Spata, Gianmarco, Bacci, Monica, Supino, Domenico, Carnevale, Silvia, Sironi, Marina, Davoudian, Sadaf, Peano, Clelia, Landi, Francesco, Di Marco, Fabiano, Raimondi, Federico, Gianatti, Andrea, Angelini, Claudio, Rambaldi, Alessandro, Garlanda, Cecilia, Ciccarelli, Michele, Cecconi, Maurizio, Mantovani, Alberto

“…Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity, involved in resistance to selected pathogens and in the regulation of…”
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Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus by Doni, Andrea, Parente, Raffaella, Laface, Ilaria, Magrini, Elena, Cunha, Cristina, Colombo, Federico Simone, Lacerda, João, Campos, António, Mapelli, Sarah N., Petroni, Francesca, Porte, Rémi, Schorn, Tilo, Inforzato, Antonio, Mercier, Toine, Lagrou, Katrien, Maertens, Johan, Lambris, John D., Bottazzi, Barbara, Garlanda, Cecilia, Botto, Marina, Carvalho, Agostinho, Mantovani, Alberto

“…© The Author(s) 2021. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer by Zoma, Marita, Curti, Laura, Shinde, Dheeraj, Albino, Domenico, Mitra, Abhishek, Sgrignani, Jacopo, Mapelli, Sarah N., Sandrini, Giada, Civenni, Gianluca, Merulla, Jessica, Chiorino, Giovanna, Kunderfranco, Paolo, Cacciatore, Alessia, Kokanovic, Aleksandra, Rinaldi, Andrea, Cavalli, Andrea, Catapano, Carlo V., Carbone, Giuseppina M.

“…The TMPRSS2-ERG gene fusion is the most frequent alteration observed in human prostate cancer. However, its role in disease progression is still unclear. In…”
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A cytokine/PTX3 prognostic index as a predictor of mortality in sepsis by Davoudian, Sadaf, Piovani, Daniele, Desai, Antonio, Mapelli, Sarah N., Leone, Roberto, Sironi, Marina, Valentino, Sonia, Silva-Gomes, Rita, Stravalaci, Matteo, Asgari, Fatemeh, Madera, Alessandra, Piccinini, Daniele, Fedeli, Carlo, Comina, Denise, Bonovas, Stefanos, Voza, Antonio, Mantovani, Alberto, Bottazzi, Barbara

“…Background Early prognostic stratification of patients with sepsis is a difficult clinical challenge. Aim of this study was to evaluate novel molecules in…”
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Deciphering the complexity of human non-coding promoter-proximal transcriptome by Mapelli, Sarah N, Napoli, Sara, Pisignano, Giuseppina, Garcia-Escudero, Ramon, Carbone, Giuseppina M, Catapano, Carlo V

“…Abstract Motivation Long non-coding RNAs (lncRNAs) have gained increasing relevance in epigenetic regulation and nuclear functional organization…”
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Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis by Gonçales, Relber A, Bastos, Helder Novais, Duarte-Oliveira, Cláudio, Antunes, Daniela, Sokhatska, Oksana, Jacob, Maria, Rolo, Rui, Campos, Cláudia F, Sasaki, Sergio D, Donato, Alessia, Mapelli, Sarah N, Costa, Sandra, Moura, Conceição Souto, Delgado, Luís, Morais, António, Torrado, Egídio, van de Veerdonk, Frank L, Weichhart, Thomas, Lambris, John D, Silvestre, Ricardo, Garlanda, Cecilia, Mantovani, Alberto, Cunha, Cristina, Carvalho, Agostinho

“…Sarcoidosis is a multisystemic inflammatory disease characterized by the formation of granulomas in response to persistent stimuli. The long pentraxin PTX3…”
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A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers by Pisignano, Giuseppina, Napoli, Sara, Magistri, Marco, Mapelli, Sarah N., Pastori, Chiara, Di Marco, Stefano, Civenni, Gianluca, Albino, Domenico, Enriquez, Claudia, Allegrini, Sara, Mitra, Abhishek, D’Ambrosio, Gioacchino, Mello-Grand, Maurizia, Chiorino, Giovanna, Garcia-Escudero, Ramon, Varani, Gabriele, Carbone, Giuseppina M., Catapano, Carlo V.

“…Long noncoding RNAs are emerging players in the epigenetic machinery with key roles in development and diseases. Here we uncover a complex network comprising a…”
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Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19 by Asselta, Rosanna, Paraboschi, Elvezia Maria, Stravalaci, Matteo, Invernizzi, Pietro, Bonfanti, Paolo, Biondi, Andrea, Pagani, Isabel, Pedotti, Mattia, Doni, Andrea, Scavello, Francesco, Mapelli, Sarah N., Sironi, Marina, Perucchini, Chiara, Varani, Luca, Matkovic, Milos, Cavalli, Andrea, Cesana, Daniela, Gallina, Pierangela, Pedemonte, Nicoletta, Capurro, Valeria, Clementi, Nicola, Mancini, Nicasio, Bayarri-Olmos, Rafael, Garred, Peter, Rappuoli, Rino, Duga, Stefano, Bottazzi, Barbara, Uguccioni, Mariagrazia, Vicenzi, Elisa, Mantovani, Alberto, Garlanda, Cecilia

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Natural antisense transcripts drive a regulatory cascade controlling c-MYC transcription by Napoli, Sara, Piccinelli, Valentina, Mapelli, Sarah N., Pisignano, Giuseppina, Catapano, Carlo V.

“…Cis-natural antisense transcripts (cis-NATs) are long noncoding RNAs transcribed from the opposite strand and overlapping coding and noncoding genes on the…”
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The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19 by Scavello, Francesco, Brunetta, Enrico, Mapelli, Sarah N., Nappi, Emanuele, García Martín, Ian David, Sironi, Marina, Leone, Roberto, Solano, Simone, Angelotti, Giovanni, Supino, Domenico, Carnevale, Silvia, Zhong, Hang, Magrini, Elena, Stravalaci, Matteo, Protti, Alessandro, Santini, Alessandro, Costantini, Elena, Savevski, Victor, Voza, Antonio, Bottazzi, Barbara, Bartoletti, Michele, Cecconi, Maurizio, Mantovani, Alberto, Morelli, Paola, Tordato, Federica, Garlanda, Cecilia

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A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors) by Mapelli, Sarah N, Albino, Domenico, Mello-Grand, Maurizia, Shinde, Dheeraj, Scimeca, Manuel, Bonfiglio, Rita, Bonanno, Elena, Chiorino, Giovanna, Garcia-Escudero, Ramon, Catapano, Carlo V, Carbone, Giuseppina M

“…In this study, we extracted prostate cell-specific gene sets (metagenes) to define the epithelial differentiation status of prostate cancers and, using a…”
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Transcriptional Reprogramming and Novel Therapeutic Approaches for Targeting Prostate Cancer Stem Cells by Civenni, Gianluca, Albino, Domenico, Shinde, Dheeraj, Vázquez, Ramiro, Merulla, Jessica, Kokanovic, Aleksandra, Mapelli, Sarah N, Carbone, Giuseppina M, Catapano, Carlo V

“…Prostate cancer is the most common malignancy in men and the second cause of cancer-related deaths in western countries. Despite the progress in the treatment…”
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Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12, 176 by Mapelli, Sarah, Albino, Domenico, Mello-Grand, Maurizia, Shinde, Dheeraj, Scimeca, Manuel, Bonfiglio, Rita, Bonanno, Elena, Chiorino, Giovanna, Garcia-Escudero, Ramon, Catapano, Carlo, Carbone, Giuseppina

“…There is an error in the title of the paper [...]…”
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Incidence and Microbiology of Hospital-Acquired Infections in COVID-19 Patients between the First and the Second Outbreak of the SARS-CoV-2 Pandemic: A Retrospective, Observational Study by Nicolò, Corti, Federica, Tordato, De Nadai, Guendalina, Sarah, Mapelli, Cecilia, Garlanda, Daria, Pocaterra, Maddalena, Casana, Paolo, Bonfanti, Paola, Morelli

“…With almost 638 million cases and over 6 million deaths worldwide, the SARS-CoV-2 pandemic represents an unprecedented healthcare challenge. Although the…”
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Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression by Magrini, Elena, Di Marco, Sabrina, Mapelli, Sarah N, Perucchini, Chiara, Pasqualini, Fabio, Donato, Alessia, Guevara Lopez, Maria de la Luz, Carriero, Roberta, Ponzetta, Andrea, Colombo, Piergiuseppe, Cananzi, Ferdinando, Supino, Domenico, Reis, Edimara S, Peano, Clelia, Inforzato, Antonio, Jaillon, Sebastien, Doni, Andrea, Lambris, John D, Mantovani, Alberto, Garlanda, Cecilia

“…Complement has emerged as a component of tumor promoting inflammation. We conducted a systematic assessment of the role of complement activation and effector…”
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Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer by Shinde, Dheeraj, Albino, Domenico, Zoma, Marita, Mutti, Azzurra, Mapelli, Sarah N., Civenni, Gianluca, Kokanovic, Aleksandra, Merulla, Jessica, Perez-Escuredo, Jhudit, Costales, Paula, Morìs, Francisco, Catapano, Carlo V., Carbone, Giuseppina M.

“…The TMPRSS2-ERG gene fusion is the most frequent genetic rearrangement in prostate cancers and results in broad transcriptional reprogramming and major…”
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Prostate Osteoblast-Like Cells: A Reliable Prognostic Marker of Bone Metastasis in Prostate Cancer Patients by Mauriello, A., Bonanno, Elena, Schillaci, Orazio, Ciuffa, Sara, Carbone, Giuseppina Maria, Catapano, Carlo V., Mapelli, Sarah Natalia, Bonfiglio, Rita, Urbano, Nicoletta, Scimeca, Manuel, Tavolozza, Mario

“…The main aim of this study was to investigate the putative association among the presence of prostate cancer cells, defined as prostate osteoblast-like cells…”
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