Search Results - "Mapagu, Cristina"

Response rates to second-line platinum-based therapy in ovarian cancer patients challenge the clinical definition of platinum resistance by Lindemann, Kristina, Gao, Bo, Mapagu, Cristina, Fereday, Sian, Emmanuel, Catherine, Alsop, Kathryn, Traficante, Nadia, Harnett, Paul R., Bowtell, David D.L., deFazio, Anna

“…The aim of this study was to compare response rates and survival in women with “platinum resistant” epithelial ovarian cancer (EOC) who received further…”
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Older age should not be a barrier to testing for somatic variants in homologous recombination DNA repair-related genes in patients with high-grade serous ovarian carcinoma by Pitiyarachchi, Omali, Lee, Yeh Chen, Sim, Hao-Wen, Srirangan, Sivatharsny, Mapagu, Cristina, Kirk, Judy, Harnett, Paul R., Balleine, Rosemary L., Bowtell, David D.L., Samimi, Goli, Brand, Alison H., Marsh, Deborah J., Beale, Philip, Anderson, Lyndal, Bouantoun, Natalie, Provan, Pamela, Ramus, Susan J., DeFazio, Anna, Friedlander, Michael

“…•7% somatic BRCA1/2 pathogenic variant (PV) rate in older high-grade serous ovarian carcinoma (HGSC) patients.•Overall somatic PV frequency in 13 homologous…”
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PARAGON (ANZGOG-0903): a phase 2 study of anastrozole in asymptomatic patients with estrogen and progesterone receptor-positive recurrent ovarian cancer and CA125 progression by Kok, Peey Sei, Beale, Philip, O'Connell, Rachel L, Grant, Peter, Bonaventura, Tony, Scurry, James, Antill, Yoland, Goh, Jeffrey, Sjoquist, Katrin, DeFazio, Anna, Mapagu, Cristina, Amant, Frederic, Friedlander, Michael

“…A subset of patients with recurrent ovarian cancer (ROC) may benefit from antiestrogen therapy with higher response rates reported in tumors that are strongly…”
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Abstract A48: Antiapoptotic gene expression and sensitivity to BH3-mimetics in chemoresistant, high-grade serous ovarian cancer cell lines by Mapagu, Cristina, Srirangan, Sivatharsny, Au-Yeung, George, Harnett, Paul R., Bowtell, David D., deFazio, Anna

“…Abstract Introduction: The development of chemotherapy resistance is common in relapsed high-grade serous ovarian cancer (HGSOC). An understanding of…”
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Abstract 2787: Identifying predictive markers of endocrine response in high-grade serous ovarian cancer using RNA sequencing by Mapagu, Cristina, Fereday, Sian, Bowtell, David D., Harnett, Paul R., deFazio, Anna

“…Abstract Epithelial ovarian cancer is a complex disease and patients vary considerably in response to treatment. A subset of patients responds well to…”
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Abstract 2584: Mutations in low-grade serous ovarian cancer and response to BRAF and MEK inhibitors by Moujaber, Tania, Etemadmoghadam, Dariush, Mapagu, Cristina, Kennedy, Catherine, Chiew, Yoke-Eng, Kan, Casina, Nevins, Nikilyn, Srirangan, Sivatharsny, Fereday, Sian, Traficante, Nadia, group, Australian Ovarian Cancer Study, Bowtell, David, Balleine, Rosemary, Harnett, Paul, deFazio, Anna

“…Abstract Low-grade serous ovarian cancer (LGSC) responds poorly to platinum based chemotherapy and is characterized by activating RAS-MAPK pathway mutations,…”
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Clinical and molecular profile of young adults with early‐onset colorectal cancer: Experience from four Australian tertiary centers by Siu, Derrick Ho Wai, Ali, Arwa, Tjokrowidjaja, Angelina, De Silva, Madhawa, Lee, Joanna, Clingan, Philip R., Aghmesheh, Morteza, Brungs, Daniel, Mapagu, Cristina, Goldstein, David, O'Neill, Siobhan, Liauw, Winston S., Sjoquist, Katrin M., Thomas, David, Pavlakis, Nick, Clarke, Stephen J., Diakos, Connie, Chantrill, Lorraine A.

“…Background Patients with early‐onset colorectal cancer (EO‐CRC) have unique characteristics. Contemporary data on the pathological and molecular features, and…”
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Paragon (ANZGOG-0903): Phase 2 Study of Anastrozole in Women With Estrogen or Progesterone Receptor-Positive Platinum-Resistant or -Refractory Recurrent Ovarian Cancer by Bonaventura, Anthony, OʼConnell, Rachel L, Mapagu, Cristina, Beale, Philip J, McNally, Orla M, Mileshkin, Linda R, Grant, Peter T, Hadley, Alison M, Goh, Jeffery C H, Sjoquist, Katrin M, Martyn, Julie, DeFazio, Anna, Scurry, James, Friedlander, Michael L

“…There is some evidence that a subset of patients with recurrent ovarian cancer may benefit from antiestrogen therapy. The Paragon study is a basket protocol…”
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Screening for hepatitis C in sexual health clinic attendees by Mapagu, M Cristina, Martin, Sarah J, Currie, Marian J, Bowden, Francis J

“…Hepatitis C virus (HCV) prevalence has been shown to be higher in some sexual health clinic attendees than the general population. Screening for HCV in sexual…”
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