Search Results - "Maoz, Myriam"

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease by Moss, Joshua, Magenheim, Judith, Neiman, Daniel, Zemmour, Hai, Loyfer, Netanel, Korach, Amit, Samet, Yaacov, Maoz, Myriam, Druid, Henrik, Arner, Peter, Fu, Keng-Yeh, Kiss, Endre, Spalding, Kirsty L., Landesberg, Giora, Zick, Aviad, Grinshpun, Albert, Shapiro, A. M. James, Grompe, Markus, Wittenberg, Avigail Dreazan, Glaser, Benjamin, Shemer, Ruth, Kaplan, Tommy, Dor, Yuval

“…Methylation patterns of circulating cell-free DNA (cfDNA) contain rich information about recent cell death events in the body. Here, we present an approach for…”
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G Protein-Coupled Receptors in Cancer by Bar-Shavit, Rachel, Maoz, Myriam, Kancharla, Arun, Nag, Jeetendra Kumar, Agranovich, Daniel, Grisaru-Granovsky, Sorina, Uziely, Beatrice

“…Despite the fact that G protein-coupled receptors (GPCRs) are the largest signal-conveying receptor family and mediate many physiological processes, their role…”
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ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin by Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ben Ya’acov, Ami, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir

“…Cell-free DNA (cfDNA) in human plasma provides access to molecular information about the pathological processes in the organs or tumors from which it…”
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Short report: Plasma based biomarkers detect radiation induced brain injury in cancer patients treated for brain metastasis: A pilot study by Makranz, Chen, Lubotzky, Asael, Zemmour, Hai, Shemer, Ruth, Glaser, Benjamin, Cohen, Jonathan, Maoz, Myriam, Sapir, Eli, Wygoda, Marc, Peretz, Tamar, Weizman, Noam, Feldman, Jon, Abrams, Ross A, Lossos, Alexander, Dor, Yuval, Zick, Aviad

“…Background Radiotherapy has an important role in the treatment of brain metastases but carries risk of short and/or long-term toxicity, termed…”
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Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin by Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ben Ya’acov, Ami, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir

“…A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-00831-9…”
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Author Correction: ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin by Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ben Ya’acov, Ami, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir

“…A Correction to this paper has been published: https://doi.org/10.1038/s41587-021-00853-3…”
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Clinical Implications of Sub-grouping HER2 Positive Tumors by Amplicon Structure and Co-amplified Genes by Maoz, Myriam, Devir, Michal, Inbar, Michal, Inbar-Daniel, Ziva, Sherill-Rofe, Dana, Bloch, Idit, Meir, Karen, Edelman, David, Azzam, Salah, Nechushtan, Hovav, Maimon, Ofra, Uziely, Beatrice, Kadouri, Luna, Sonnenblick, Amir, Eden, Amir, Peretz, Tamar, Zick, Aviad

“…ERBB2 amplification is a prognostic marker for aggressive tumors and a predictive marker for prolonged survival following treatment with HER2 inhibitors. We…”
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Author Correction: Clinical Implications of Sub-grouping HER2 Positive Tumors by Amplicon Structure and Co-amplified Genes by Maoz, Myriam, Devir, Michal, Inbar, Michal, Inbar-Daniel, Ziva, Sherill-Rofe, Dana, Bloch, Idit, Meir, Karen, Edelman, David, Azzam, Salah, Nechushtan, Hovav, Maimon, Ofra, Uziely, Beatrice, Kadouri, Luna, Sonnenblick, Amir, Eden, Amir, Peretz, Tamar, Zick, Aviad

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Differential expression of Protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples by Grisaru‐Granovsky, Sorina, Salah, Zaidoun, Maoz, Myriam, Pruss, Diana, Beller, Uziel, Bar‐Shavit, Rachel

“…Protease activated receptors (PAR) form a family of G‐protein coupled receptors (GPCR) encoding their own ligands and uniquely activated via proteolytic…”
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Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance by Cohen, Irit, Maoz, Myriam, Turm, Hagit, Grisaru-Granovsky, Sorina, Maly, Bella, Uziely, Beatrice, Weiss, Einat, Abramovitch, Rinat, Gross, Eithan, Barzilay, Oded, Qiu, Yun, Bar-Shavit, Rachel

“…While protease-activated-receptor 1 (PAR(1)) plays a central role in tumor progression, little is known about the cell signaling involved. We show here the…”
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PAR1 plays a role in epithelial malignancies: Transcriptional regulation and novel signaling pathway by Bar‐Shavit, Rachel, Turm, Hagit, Salah, Zaidoun, Maoz, Myriam, Cohen, Irit, Weiss, Einat, Uziely, Beatrice, Grisaru‐Granovsky, Sorina

“…Protease‐activated receptor1 (PAR1) is the first and prototype member of an established PAR family comprising four members. The role of PAR1 in tumor biology…”
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Protease-Activated Receptor-1 (hPar1), A Survival Factor Eliciting Tumor Progression by Salah, Zaidoun, Maoz, Myriam, Pokroy, Elisheva, Lotem, Michal, Bar-Shavit, Rachel, Uziely, Beatrice

“…Although ample evidence point to the central involvement of protease activated receptor-1 ( PAR1 ) in tumor progression, little is known about the fate of the…”
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Correction: Etk/Bmx Regulates Proteinase-Activated-Receptor1 (PAR 1 ) in Breast Cancer Invasion: Signaling Partners, Hierarchy and Physiological Significance by Cohen, Irit, Maoz, Myriam, Turm, Hagit, Grisaru-Granovsky, Sorina, Maly, Bella, Uziely, Beatrice, Weiss, Einat, Abramovitch, Rinat, Gross, Eithan, Barzilay, Oded, Qiu, Yun, Bar-Shavit, Rachel

“…Qiu Y, Robinson D, Pretlow TG, Kung HJ (1998) Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase…”
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DVL as a scaffold protein capturing classical GPCRs by Turm, Hagit, Grisaru-Granovsky, Sorina, Maoz, Myriam, Offermanns, Stefan, Bar-Shavit, Rachel

“…The classical G-protein-coupled receptors (GPCRs) are characterized by their ability to interact with heterotrimeric G proteins upon activation and by…”
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PAR Genes: Molecular Probes to Pathological Assessment in Breast Cancer Progression by Maoz, Myriam, Uziely, Beatrice, Bar-Shavit, Rachel, Maly, Bella, Cohen, Irit, Turm, Hagit

“…Taking the issue of tumor categorization a step forward and establish molecular imprints to accompany histopathological assessment is a challenging task. This…”
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Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics by Fedyuk, Vadim, Erez, Nir, Furth, Noa, Beresh, Olga, Andreishcheva, Ekaterina, Shinde, Abhijeet, Jones, Daniel, Zakai, Barak Bar, Mavor, Yael, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E., Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Zick, Aviad, Ron, Guy, Shema, Efrat

“…The analysis of cell-free DNA (cfDNA) in plasma provides information on pathological processes in the body. Blood cfDNA is in the form of nucleosomes, which…”
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Cancer driver G-protein coupled receptor (GPCR) induced β-catenin nuclear localization: the transcriptional junction by Nag, Jeetendra Kumar, Rudina, Tatyana, Maoz, Myriam, Grisaru-Granovsky, Sorina, Uziely, Beatrice, Bar-Shavit, Rachel

“…G protein-coupled receptors (GPCRs) comprise the main signal-transmitting components in the cell membrane. Over the past several years, biochemical and…”
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PAR 1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors by Grisaru-Granovsky, Sorina, Kumar Nag, Jeetendra, Zakar, Liat, Rudina, Tatyana, Lal Gupta, Chhedi, Maoz, Myriam, Kozlova, Daria, Bar-Shavit, Rachel

“…While the involvement of protease-activated receptors (PARs) in the physiological regulation of human placenta development, as in tumor biology, is recognized,…”
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A universal cell‐free DNA approach for response prediction to preoperative chemoradiation in rectal cancer by Grinshpun, Albert, Kustanovich, Anatoli, Neiman, Daniel, Lehmann‐Werman, Roni, Zick, Aviad, Meir, Karen, Vainer, Elez, Granit, Roy Z., Arad, Amit, Daskal, Noa, Schwartz, Ruth, Sapir, Eli, Maoz, Myriam, Tahover, Esther, Moss, Joshua, Ben‐Dov, Iddo Z., Peretz, Tamar, Hubert, Ayala, Shemer, Ruth, Dor, Yuval

“…The standard treatment approach for stage II/III rectal cancer is neoadjuvant chemoradiation therapy (nCRT) followed by surgery. In recent years, new treatment…”
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Clinical and genetic characteristics of carriers of the TP53 c.541C > T, p.Arg181Cys pathogenic variant causing hereditary cancer in patients of Arab-Muslim descent by Arnon, Johnathan, Zick, Aviad, Maoz, Myriam, Salaymeh, Nada, Gugenheim, Ahinoam, Marouani, MazalTov, Mor, Eden, Hamburger, Tamar, Saadi, Nagam, Elia, Anna, Ganz, Gael, Fahham, Duha, Meirovitz, Amichay, Kadouri, Luna, Meiner, Vardiella, Yablonski-Peretz, Tamar, Shkedi-Rafid, Shiri

“…TP53 pathogenic variants cause Li-Fraumeni syndrome (LFS), with some variants causing an attenuated phenotype. Herein, we describe the clinical phenotype and…”
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