Search Results - "Mao, Yizhe"
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Cross-platform comparison of immune signatures in immunotherapy-treated patients with advanced melanoma using a rank-based scoring approach
Published in Journal of translational medicine (13-04-2023)“…Gene expression profiling is increasingly being utilised as a diagnostic, prognostic and predictive tool for managing cancer patients. Single-sample scoring…”
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Classification of the tumor immune microenvironment and associations with outcomes in patients with metastatic melanoma treated with immunotherapies
Published in Journal for immunotherapy of cancer (01-10-2023)“…BackgroundTumor microenvironment (TME) characteristics are potential biomarkers of response to immune checkpoint inhibitors in metastatic melanoma. This study…”
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82 Spatial immunophenotyping of longitudinal metastatic melanoma specimens to identify biomarkers of response and resistance to combination anti-LAG-3 + anti-PD-1-based immunotherapies
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundDual inhibition of the lymphocyte activation gene 3 (LAG-3) and programmed cell death 1 (PD-1) receptors has significantly improved clinical outcomes…”
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Tissue-based Profiling Techniques to Achieve Precision Medicine in Cancer: Opportunities and Challenges in Melanoma
Published in Clinical cancer research (07-10-2024)“…Immunotherapies targeting the programmed cell death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) checkpoint receptors have revolutionised the…”
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Abstract 5701: Predictive biomarker models of immunotherapy response in patients with metastatic melanoma: genomic, transcriptomic, and immune profiles from the Personalised Immunotherapy Program (PIP)
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: While immune checkpoint inhibitors (ICI) have become the standard-of-care for advanced melanoma patients, only half of treated patients…”
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