Search Results - "Mao, Yanfei"

Multiplex Gene Editing in Rice Using the CRISPR-Cpf1 System by Wang, Mugui, Mao, Yanfei, Lu, Yuming, Tao, Xiaoping, Zhu, Jian-kang

“…Dear Editor, The class 2/type Ⅱ clustered regularly interspaced short palindromic repeat （CRISPR）/Cas9 system has been used successfully for simultaneous…”
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Gene Targeting by Homology-Directed Repair in Rice Using a Geminivirus-Based CRISPR/Cas9 System by Wang, Mugui, Lu, Yuming, Botella, José Ramón, Mao, Yanfei, Hua, Kai, Zhu, Jian-kang

“…Dear Editor, Rice （Oryza sativa） is the staple food for more than half of the world＇s population. Technologies enabling precise and efficient DNA knock-in or…”
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Construction of Axially Chiral Arylborons via Atroposelective Miyaura Borylation by Yang, Kai, Mao, Yanfei, Xu, Jie, Wang, Hao, He, Yong, Li, Wangyang, Song, Qiuling

“…Compared with the well-developed centrally chiral boron chemistry, C–B axially chiral chemistry remains elusive and challenging. Herein we report the first…”
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Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis by Feng, Zhengyan, Mao, Yanfei, Xu, Nanfei, Zhang, Botao, Wei, Pengliang, Yang, Dong-Lei, Wang, Zhen, Zhang, Zhengjing, Zheng, Rui, Yang, Lan, Zeng, Liang, Liu, Xiaodong, Zhu, Jian-Kang

“…The CRISPR (clustered regularly interspaced short palindromic repeat)/Cas (CRISPR-associated) system has emerged as a powerful tool for targeted gene editing…”
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Efficient genome editing in plants using a CRISPR/Cas system by Feng, Zhengyan, Zhang, Botao, Ding, Wona, Liu, Xiaodong, Yang, Dong-Lei, Wei, Pengliang, Cao, Fengqiu, Zhu, Shihua, Zhang, Feng, Mao, Yanfei, Zhu, Jian-Kang

“…Dear Editor, In the past few years, the development of sequence- specific DNA nucleases has progressed rapidly and such nucleases have shown their power in…”
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Application of the CRISPR-Cas System for Efficient Genome Engineering in Plants by Mao, Yanfei, Zhang, Hui, Xu, Nanfei, Zhang, Botao, Gou, Feng, Zhu, Jian-Kang

“…Dear Editor, Recently, engineered endonucleases, such as Zinc-Finger Nucleases （ZFNs） （Carroll, 2011）, Transcription Activator-Like Effector Nucleases （TALENs）…”
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The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation by Zhang, Hui, Zhang, Jinshan, Wei, Pengliang, Zhang, Botao, Gou, Feng, Feng, Zhengyan, Mao, Yanfei, Yang, Lan, Zhang, Heng, Xu, Nanfei, Zhu, Jian-Kang

“…The CRISPR/Cas9 system has been demonstrated to efficiently induce targeted gene editing in a variety of organisms including plants. Recent work showed that…”
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A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis by Zhang, Zhengjing, Mao, Yanfei, Ha, Si, Liu, Wenshan, Botella, Jose Ramon, Zhu, Jian-Kang

“…The recently developed CRISPR/Cas9 system is a promising technology for targeted genome editing in a variety of species including plants. However, the first…”
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Construction of C-B axial chirality via dynamic kinetic asymmetric cross-coupling mediated by tetracoordinate boron by Yang, Kai, Mao, Yanfei, Zhang, Zhihan, Xu, Jie, Wang, Hao, He, Yong, Yu, Peiyuan, Song, Qiuling

“…Catalytic dynamic kinetic asymmetric transformation (DyKAT) provides a powerful tool to access chiral stereoisomers from racemic substrates. Such…”
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microRNA319a-Targeted Brassica rapa ssp. pekinensis TCP Genes Modulate Head Shape in Chinese Cabbage by Differential Cell Division Arrest in Leaf Regions by Mao, Yanfei, Wu, Feijie, Yu, Xiang, Bai, Jinjuan, Zhong, Weili, He, Yuke

“…Leafy heads of cabbage (Brassica oleracea), Chinese cabbage (Brassica rapa), and lettuce (Lactuca saliva) are composed of extremely incurved leaves. The shape…”
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The Adrenal Cortex, an Underestimated Site of SARS-CoV-2 Infection by Mao, Yanfei, Xu, Bo, Guan, Wenbin, Xu, Dunfeng, Li, Feng, Ren, Rongrong, Zhu, Xiaoyan, Gao, Yuan, Jiang, Lai

“…The majority of the critically ill patients may have critical illness-related corticosteroid insufficiency (CIRCI). The therapeutic effect of dexamethasone may…”
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Manipulating plant RNA-silencing pathways to improve the gene editing efficiency of CRISPR/Cas9 systems by Mao, Yanfei, Yang, Xiaoxuan, Zhou, Yiting, Zhang, Zhengjing, Botella, Jose Ramon, Zhu, Jian-Kang

“…The CRISPR/Cas9 system, composed of a single-guide RNA for target recognition and a Cas9 protein for DNA cleavage, has the potential to revolutionize…”
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A Highly Efficient Cell Division-Specific CRISPR/Cas9 System Generates Homozygous Mutants for Multiple Genes in Arabidopsis by Feng, Zhengyan, Zhang, Zhengjing, Hua, Kai, Gao, Xifeng, Mao, Yanfei, Botella, Jose Ramon, Zhu, Jian-Kang

“…The CRISPR/Cas9 system has been widely used for targeted genome editing in numerous plant species. In , constitutive promoters usually result in a low…”
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miR-27a is up regulated and promotes inflammatory response in sepsis by Wang, Zhongchuan, Ruan, Zhengshang, Mao, Yanfei, Dong, Wenwen, Zhang, Yunqian, Yin, Na, Jiang, Lai

“…•miR-27a is up regulated in sepsis.•Inhibition of miR-27a reduces the expression levels of TNF-α and IL-6.•Knocking down of miR-27a reduces the phosphorylation…”
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Assessment of vocal cord movement by ultrasound in the ICU by Ruan, Zhengshang, Ren, Rongrong, Dong, Wenwen, Ma, Junjie, Xu, Zhenyu, Mao, Yanfei, Jiang, Lai

“…Purpose Ultrasound can be used to non-invasively and rapidly examine airway conditions, but vocal cord visualization with the traditional approaches is poor…”
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Proteomic Lung Analysis of Mice with Ventilator-Induced Lung Injury (VILI) Using iTRAQ-Based Quantitative Proteomics by Ding, Haoshu, Wang, Yan, Dong, Wenwen, Ren, Rongrong, Mao, Yanfei, Deng, Xiaoming

“…Ventilator-induced lung injury (VILI) has implications for mortality from acute lung injury (ALI) and for acute respiratory distress syndrome (ARDS) patients;…”
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Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats by Zheng, Xingfeng, Mao, Yanfei, Cai, Jianmei, Li, Yonghua, Liu, Wenwu, Sun, Pengling, Zhang, John H, Sun, Xuejun, Yuan, Hongbin

“…Hydrogen gas was reported to reduce reactive oxygen species and alleviate cerebral, myocardial and hepatic ischemia/reperfusion (I/R) injuries. This paper…”
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A New and Simple Design Method for End-Fire Dipole Antenna Array and Three Two-Element 24 GHz Planar End-Fire Dipole Antenna Arrays by Mao, Yanfei, E, Shiju, Zhu, Chungeng

“…For an RF system, a high-gain antenna helps to improve the equivalent isotropic radiated power (EIRP) of the transmitter and an end-fire antenna array helps to…”
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Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway by Miki, Daisuke, Zhu, Peiying, Zhang, Wencan, Mao, Yanfei, Feng, Zhengyan, Huang, Huan, Zhang, Hui, Li, Yanqiang, Liu, Renyi, Zhang, Huiming, Qi, Yijun, Zhu, Jian-Kang

“…It has been reported that double-stranded break (DSB)-induced small RNAs (diRNAs) are generated via the RNA-directed DNA methylation pathway and function in…”
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MiR-135a Protects Vascular Endothelial Cells Against Ventilator-Induced Lung Injury by Inhibiting PHLPP2 to Activate PI3K/Akt Pathway by Yan, Xiaodi, Li, Wenqian, Yang, Liye, Dong, Wenwen, Chen, Wei, Mao, Yanfei, Xu, Pingbo, Li, Dongjie, Yuan, Hongbin, Li, Yong-Hua

“…Abstract Background/Aims: Loss of endothelial barrier function plays an important role in the development of ventilator-induced lung injury (VILI). This study…”
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