Search Results - "Mao, Jian Hua"

Unsupervised Transfer Learning via Multi-Scale Convolutional Sparse Coding for Biomedical Applications by Chang, Hang, Han, Ju, Zhong, Cheng, Snijders, Antoine M., Mao, Jian-Hua

“…The capabilities of (I) learning transferable knowledge across domains; and (II) fine-tuning the pre-learned base knowledge towards tasks with considerably…”
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Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy by Zhang, Weiguo, Mao, Jian-Hua, Zhu, Wei, Jain, Anshu K., Liu, Ke, Brown, James B., Karpen, Gary H.

“…Chromosomal instability (CIN) is a hallmark of cancer that contributes to tumour heterogeneity and other malignant properties. Aberrant centromere and…”
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miR-1204 targets VDR to promotes epithelial-mesenchymal transition and metastasis in breast cancer by Liu, Xiaoyan, Bi, Lei, Wang, Qin, Wen, Mingxin, Li, Ce, Ren, Yidan, Jiao, Qinlian, Mao, Jian-Hua, Wang, Chuanxin, Wei, Guangwei, Wang, Yunshan

“…Plasmacytoma variant translocation 1 (PVT1) is an lncRNA that plays vital roles in breast cancer (BC) pathogenesis. Increasing evidence suggests that miRNAs…”
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Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance by Chen, Kun, Luan, Xiaoting, Liu, Qisha, Wang, Jianwei, Chang, Xinxia, Snijders, Antoine M., Mao, Jian-Hua, Secombe, Julie, Dan, Zhou, Chen, Jian-Huan, Wang, Zibin, Dong, Xiao, Qiu, Chen, Chang, Xiaoai, Zhang, Dong, Celniker, Susan E., Liu, Xingyin

“…Loss-of-function mutations in the histone demethylases KDM5A, KDM5B, or KDM5C are found in intellectual disability (ID) and autism spectrum disorders (ASD)…”
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FAM83 family oncogenes are broadly involved in human cancers: an integrative multi‐omics approach by Snijders, Antoine M., Lee, Sun‐Young, Hang, Bo, Hao, Wenshan, Bissell, Mina J., Mao, Jian‐Hua

“…The development of novel targeted therapies for cancer treatment requires identification of reliable targets. FAM83 (‘family with sequence similarity 83’)…”
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RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings by Ren, Shancheng, Peng, Zhiyu, Mao, Jian-Hua, Yu, Yongwei, Yin, Changjun, Gao, Xin, Cui, Zilian, Zhang, Jibin, Yi, Kang, Xu, Weidong, Chen, Chao, Wang, Fubo, Guo, Xinwu, Lu, Ji, Yang, Jun, Wei, Min, Tian, Zhijian, Guan, Yinghui, Tang, Liang, Xu, Chuanliang, Wang, Linhui, Gao, Xu, Tian, Wei, Wang, Jian, Yang, Huanming, Wang, Jun, Sun, Yinghao

“…There are remarkable disparities among patients of different races with prostate cancer; however, the mechanism underlying this difference remains unclear…”
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Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice by Cai, Ting-Ting, Ye, Xiao-Long, Li, Ru-Run, Chen, Hui, Wang, Ya-Yun, Yong, Hui-Juan, Pan, Ming-Lin, Lu, Wei, Tang, Ying, Miao, Heng, Snijders, Antoine M., Mao, Jian-Hua, Liu, Xing-Yin, Lu, Yi-Bing, Ding, Da-Fa

“…Oral administration of resveratrol is able to ameliorate the progression of diabetic nephropathy (DN); however, its mechanisms of action remain unclear. Recent…”
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FBXW7 Targets mTOR for Degradation and Cooperates with PTEN in Tumor Suppression by Mao, Jian-Hua, Kim, Il-Jin, Wu, Di, Climent, Joan, Kang, Hio Chung, DelRosario, Reyno, Balmain, Allan

“…The enzyme mTOR (mammalian target of rapamycin) is a major target for therapeutic intervention to treat many human diseases, including cancer, but very little…”
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Contribution of trace element exposure to gestational diabetes mellitus through disturbing the gut microbiome by Zhang, Yuqing, Chen, Ting, Zhang, Yiyun, Hu, Qi, Wang, Xu, Chang, Hang, Mao, Jian-Hua, Snijders, Antoine M., Xia, Yankai

“…•The link between element exposure, the gut microbiome (GM), and GDM were assessed.•GM is dramatically altered before GDM diagnosis.•Trace elements are closely…”
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A new platform for ultra-high dose rate radiobiological research using the BELLA PW laser proton beamline by Bin, Jianhui, Obst-Huebl, Lieselotte, Mao, Jian-Hua, Nakamura, Kei, Geulig, Laura D., Chang, Hang, Ji, Qing, He, Li, De Chant, Jared, Kober, Zachary, Gonsalves, Anthony J., Bulanov, Stepan, Celniker, Susan E., Schroeder, Carl B., Geddes, Cameron G. R., Esarey, Eric, Simmons, Blake A., Schenkel, Thomas, Blakely, Eleanor A., Steinke, Sven, Snijders, Antoine M.

“…Radiotherapy is the current standard of care for more than 50% of all cancer patients. Improvements in radiotherapy (RT) technology have increased tumor…”
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Haze facilitates sensitization to house dust mites in children by Ye, Qing, Zhang, Ting, Mao, Jian-hua

“…Allergy to house dust mites (HDMs) can cause allergic rhinitis, allergic asthma and allergic skin disorders, which is becoming an enormous worldwide health and…”
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Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer by Wang, Yuli, Zhang, Pengju, Wang, Yunshan, Zhan, Panpan, Liu, Chunyan, Mao, Jian-Hua, Wei, Guangwei

“…The ErbB3 receptor-binding protein EBP1 encodes two alternatively spliced isoforms P48 and P42. While there is evidence of differential roles for these…”
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Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia by Wang, Lan, Zhou, Guang-Biao, Liu, Ping, Song, Jun-Hong, Liang, Yang, Yan, Xiao-Jing, Xu, Fang, Wang, Bing-Shun, Mao, Jian-Hua, Shen, Zhi-Xiang, Chen, Sai-Juan, Chen, Zhu

“…To enhance therapeutic efficacy and reduce adverse effects, practitioners of traditional Chinese medicine (TCM) prescribe a combination of plant…”
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CUL4A Induces Epithelial-Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression by YUNSHAN WAN, MINGXIN WEN, LABARGE, Mark A, LIANG YOU, KOGAN, Scott C, GRAY, Joe W, MAO, Jian-Hua, GUANGWEI WEI, YONGWON KWON, YANGYANG XU, YUEYONG LIU, PENGJU ZHANG, XIUQUAN HE, QIN WANG, YURONG HUANG, JEN, Kuang-Yu

“…The ubiquitin ligase CUL4A has been implicated in tumorigenesis, but its contributions to progression and metastasis have not been evaluated. Here, we show…”
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The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor by Cui, Zilian, M.D., Ph.D, Ren, Shancheng, M.D., Ph.D, Lu, Ji, M.S, Wang, Fubo, M.S, Xu, Weidong, M.S, Sun, Yi, M.S, Wei, Min, M.S, Chen, Junyi, Ph.D, Gao, Xu, M.D., Ph.D, Xu, Chuanliang, M.D., Ph.D, Mao, Jian-Hua, Ph.D, Sun, Yinghao, M.D., Ph.D

“…Abstract Objective Emerging evidences implicate long noncoding RNAs (lncRNAs) are deregulated in cancer development. The purpose of the current study is to…”
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Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs by Furuta, Saori, Ren, Gang, Mao, Jian-Hua, Bissell, Mina J

“…How mammalian tissues maintain their architecture and tissue-specificity is poorly understood. Previously, we documented both the indispensable role of the…”
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The FBXW7-binding sites on FAM83D are potential targets for cancer therapy by Jiang, Xiaoyu, Wang, Yuli, Guo, Lulu, Wang, Yige, Miao, Tianshu, Ma, Lijuan, Wei, Qin, Lin, Xiaoyan, Mao, Jian-Hua, Zhang, Pengju

“…Increasing evidence shows the oncogenic function of FAM83D in human cancer, but how FAM83D exerts its oncogenic function remains largely unclear. Here, we…”
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Genetic background influences the effect of thirdhand smoke exposure on anxiety and memory in Collaborative Cross mice by He, Li, Wang, Pin, Schick, Suzyann F., Huang, Abel, Jacob, Peyton, Yang, Xu, Xia, Yankai, Snijders, Antoine M., Mao, Jian-Hua, Chang, Hang, Hang, Bo

“…Growing evidence indicates that thirdhand smoke (THS) exposure induces many adverse health effects. However, it is unclear how THS exposure affects behavior…”
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Thirdhand smoke exposure causes replication stress and impaired transcription in human lung cells by Sarker, Altaf H., Trego, Kelly S., Zhang, Weiguo, Jacob, Peyton, Snijders, Antoine M., Mao, Jian‐Hua, Schick, Suzaynn F., Cooper, Priscilla K., Hang, Bo

“…Thirdhand cigarette smoke (THS) is a newly described toxin that lingers in the indoor environment long after cigarettes have been extinguished. Emerging…”
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Coronavirus disease 2019 vaccine for children in China: when to start? Mandatory or voluntary? by Liu, Fei, Fu, Hai-Dong, Mao, Jian-Hua

“…Vaccinating children could have beneficial knock-on effects in the wider community through blocking transmission of COVID-19. [...]children and adolescents…”
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