Search Results - "Mao, Hongyuan"
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Autophagy-mediated NKG2D internalization impairs NK cell function and exacerbates radiation pneumonitis
Published in Frontiers in immunology (2023)“…Radiation pneumonitis is a critical complication that constrains the use of radiation therapy for thoracic malignancies, leading to substantial morbidity via…”
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Sortase-Mediated Protein Ligation: A New Method for Protein Engineering
Published in Journal of the American Chemical Society (10-03-2004)“…Sortase (SrtA), a transpeptidase from Staphylococcus aureus, catalyzes a cell-wall sorting reaction at an LPXTG motif by cleaving between threonine and glycine…”
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Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization
Published in Nature biotechnology (01-11-2010)“…Antibodies that modulate the activity of a target are difficult to discover with display-based approaches, which select only high-affinity binders. Mao et al …”
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Local folding coupled to RNA binding in the yeast ribosomal protein L30 1 1Edited by D. E. Draper
Published in Journal of molecular biology (01-09-1999)Get full text
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Assignment of the L30-mRNA complex using selective isotopic labeling and RNA mutants
Published in Nucleic acids research (15-10-1999)“…The helix-loop-helix structure formed in the pre-mRNA and the mRNA of L30, a ribosomal protein from the yeast Saccharomyces cerevisiae, serves as an…”
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Expression, Refolding, and Isotopic Labeling of Human Serum Albumin Domains for NMR Spectroscopy
Published in Protein expression and purification (01-12-2000)“…Many different compounds bind to human serum albumin (HSA), which can be a significant problem in the drug discovery process. To aid in the design of drug…”
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Arrayed protein library technology for therapeutic biologic discovery
Published in Biotechnology & genetic engineering reviews (01-01-2012)Get full text
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α Helix-RNA Major Groove Recognition in an HIV-1 Rev Peptide-RRE RNA Complex
Published in Science (American Association for the Advancement of Science) (13-09-1996)“…The solution structure of a human immunodeficiency virus type-1 (HIV-1) Rev peptide bound to stem-loop IIB of the Rev response element (RRE) RNA was solved by…”
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A self-cleavable sortase fusion for one-step purification of free recombinant proteins
Published in Protein expression and purification (01-09-2004)“…A new protein fusion system has been developed to generate free recombinant protein in a single affinity chromatographic step. The key component in the fusion…”
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Rational Design of Diflunisal Analogues with Reduced Affinity for Human Serum Albumin
Published in Journal of the American Chemical Society (31-10-2001)“…Many lead compounds bind to serum albumin and exhibit markedly reduced efficacy in vivo as compared to their potency in vitro. To aid in the design of…”
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11
Local folding coupled to RNA binding in the yeast ribosomal protein L30
Published in Journal of molecular biology (17-09-1999)“…The ribosomal protein L30 from yeast Saccharomyces cerevisiae auto-regulates its own synthesis by binding to a structural element in both its pre-mRNA and its…”
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A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex
Published in Nature structural biology (01-12-1999)“…The yeast Saccharomyces cerevisiae ribosomal protein L30 negatively autoregulates its production by binding to a helix-loop-helix structure formed in its…”
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1H, 13C and 15N resonance assignments and secondary structure of the human protein tyrosine phosphatase, PRL-2
Published in Journal of biomolecular NMR (01-12-2003)Get full text
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Letter to the Editor: 1H, 13C and 15N resonance assignments and secondary structure of the human protein tyrosine phosphatase, PRL-2
Published in Journal of biomolecular NMR (01-12-2003)Get full text
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Improved large scale culture of Methylophilus methylotrophus for super(13)C/ super(15)N labeling and random fractional deuteration of ribonucleotides
Published in Nucleic acids research (01-12-1996)“…Isotopic labeling of RNA with super(13)C and super(15)N has become a routine procedure in structural studies by NMR spectroscopy. The methodology in this paper…”
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Improved Large Scale Culture of Methylophilus Methylotrophus for 13C/15N Labeling and Random Fractional Deuteration of Ribonucleotides
Published in Nucleic acids research (01-12-1996)“…Isotopic labeling of RNA with 13C and 15N has become a routine procedure in structural studies by NMR spectroscopy. The methodology in this paper describes the…”
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17
Alpha helix-RNA major groove recognition in an HIV-1 Rev peptide-RRE DNA complex
Published in Science (American Association for the Advancement of Science) (13-09-1996)“…The solution structure of a human immunodeficiency virus type-1 (HIV-1) Rev peptide bound to stem-loop IIB of the Rev response element (RRE) RNA was solved by…”
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