Search Results - "Mao, Diane D."

CDC20 regulates sensitivity to chemotherapy and radiation in glioblastoma stem cells by Mao, Diane D, Cleary, Ryan T, Gujar, Amit, Mahlokozera, Tatenda, Kim, Albert H

“…Glioblastoma stem cells (GSCs) are an important subpopulation in glioblastoma, implicated in tumor growth, tumor recurrence, and radiation resistance…”
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An NAD⁺-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma by Gujar, Amit D., Le, Son, Mao, Diane D., Dadey, David Y. A., Turski, Alice, Sasaki, Yo, Aum, Diane, Luo, Jingqin, Dahiya, Sonika, Yuan, Liya, Rich, Keith M., Milbrandt, Jeffrey, Hallahan, Dennis E., Yano, Hiroko, Tran, David D., Kim, Albert H.

“…Accumulating evidence suggests cancer cells exhibit a dependency on metabolic pathways regulated by nicotinamide adenine dinucleotide (NAD⁺). Nevertheless, how…”
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Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma by Mahlokozera, Tatenda, Patel, Bhuvic, Chen, Hao, Desouza, Patrick, Qu, Xuan, Mao, Diane D., Hafez, Daniel, Yang, Wei, Taiwo, Rukayat, Paturu, Mounica, Salehi, Afshin, Gujar, Amit D., Dunn, Gavin P., Mosammaparast, Nima, Petti, Allegra A., Yano, Hiroko, Kim, Albert H.

“…The pluripotency transcription factor SOX2 is essential for the maintenance of glioblastoma stem cells (GSC), which are thought to underlie tumor growth,…”
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High incidence of TERT mutation in brain tumor cell lines by Johanns, Tanner M., Fu, Yujie, Kobayashi, Dale K., Mei, Yu, Dunn, Ian F., Mao, Diane D., Kim, Albert H., Dunn, Gavin P.

“…TERT promoter gene mutations are highly recurrent in malignant glioma. However, little information exists regarding their presence in experimental brain tumor…”
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Gonadal sex patterns p21-induced cellular senescence in mouse and human glioblastoma by Broestl, Lauren, Warrington, Nicole M., Grandison, Lucia, Abou-Antoun, Tamara, Tung, Olivia, Shenoy, Saraswati, Tallman, Miranda M., Rhee, Gina, Yang, Wei, Sponagel, Jasmin, Yang, Lihua, Kfoury-Beaumont, Najla, Hill, Cameron M., Qanni, Sulaiman A., Mao, Diane D., Kim, Albert H., Stewart, Sheila A., Venere, Monica, Luo, Jingqin, Rubin, Joshua B.

“…Males exhibit higher incidence and worse prognosis for the majority of cancers, including glioblastoma (GBM). Disparate survival may be related to sex-biased…”
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PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells by Brooks, Michael D, Jackson, Erin, Warrington, Nicole M, Luo, Jingqin, Forys, Jason T, Taylor, Sara, Mao, Diane D, Leonard, Jeffrey R, Kim, Albert H, Piwnica-Worms, David, Mitra, Robi D, Rubin, Joshua B

“…Cell-cell interactions between tumor cells and constituents of their microenvironment are critical determinants of tumor tissue biology and therapeutic…”
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Defining phenotypic and functional heterogeneity of glioblastoma stem cells by mass cytometry by Galdieri, Luciano, Jash, Arijita, Malkova, Olga, Mao, Diane D, DeSouza, Patrick, Chu, Yunli E, Salter, Amber, Campian, Jian L, Naegle, Kristen M, Brennan, Cameron W, Wakimoto, Hiroaki, Oh, Stephen T, Kim, Albert H, Chheda, Milan G

“…Most patients with glioblastoma (GBM) die within 2 years. A major therapeutic goal is to target GBM stem cells (GSCs), a subpopulation of cells that contribute…”
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A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells by Mao, Diane D., Gujar, Amit D., Mahlokozera, Tatenda, Chen, Ishita, Pan, Yanchun, Luo, Jingqin, Brost, Taylor, Thompson, Elizabeth A., Turski, Alice, Leuthardt, Eric C., Dunn, Gavin P., Chicoine, Michael R., Rich, Keith M., Dowling, Joshua L., Zipfel, Gregory J., Dacey, Ralph G., Achilefu, Samuel, Tran, David D., Yano, Hiroko, Kim, Albert H.

“…Glioblastoma harbors a dynamic subpopulation of glioblastoma stem-like cells (GSCs) that can propagate tumors in vivo and is resistant to standard…”
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Diffusion Histology Imaging Combining Diffusion Basis Spectrum Imaging (DBSI) and Machine Learning Improves Detection and Classification of Glioblastoma Pathology by Ye, Zezhong, Price, Richard L, Liu, Xiran, Lin, Joshua, Yang, Qingsong, Sun, Peng, Wu, Anthony T, Wang, Liang, Han, Rowland H, Song, Chunyu, Yang, Ruimeng, Gary, Sam E, Mao, Diane D, Wallendorf, Michael, Campian, Jian L, Li, Jr-Shin, Dahiya, Sonika, Kim, Albert H, Song, Sheng-Kwei

“…Glioblastoma (GBM) is one of the deadliest cancers with no cure. While conventional MRI has been widely adopted to examine GBM clinically, accurate…”
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GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors by Fu, Yujie, Liu, Connor J., Kobayashi, Dale K., Johanns, Tanner M., Bowman-Kirigin, Jay A., Schaettler, Maximilian O., Mao, Diane D., Bender, Diane, Kelley, Diane G., Uppaluri, Ravindra, Bi, Wenya Linda, Dunn, Ian F., Tao, Yu, Luo, Jingqin, Kim, Albert H., Dunn, Gavin P.

“…Encouraging clinical results using immune checkpoint therapies to target the PD-1 axis in a variety of cancer types have paved the way for new immune therapy…”
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TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma by Sun, Rui, Han, Rowland, McCornack, Colin, Khan, Saad, Tabor, G Travis, Chen, Yun, Hou, Jinchao, Jiang, Haowu, Schoch, Kathleen M, Mao, Diane D, Cleary, Ryan, Yang, Alicia, Liu, Qin, Luo, Jingqin, Petti, Allegra, Miller, Timothy M, Ulrich, Jason D, Holtzman, David M, Kim, Albert H

“…Triggering receptor expressed on myeloid cells 2 (TREM2) plays important roles in brain microglial function in neurodegenerative diseases, but the role of…”
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Biological and therapeutic implications of multisector sequencing in newly diagnosed glioblastoma by Mahlokozera, Tatenda, Vellimana, Ananth K, Li, Tiandao, Mao, Diane D, Zohny, Zohny S, Kim, David H, Tran, David D, Marcus, Daniel S, Fouke, Sarah J, Campian, Jian L, Dunn, Gavin P, Miller, Christopher A, Kim, Albert H

“…Diagnostic workflows for glioblastoma (GBM) patients increasingly include DNA sequencing-based analysis of a single tumor site following biopsy or resection…”
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Establishing Primary Human Glioblastoma Adherent Cultures from Operative Specimens by Gujar, Amit D, Mao, Diane D, Finlay, John B, Kim, Albert H

“…This chapter describes a method for isolation, maintenance, and propagation of primary glioblastoma (GBM) cells in adherent monolayer cultures from patient…”
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IMMU-35. TREM2 RESTRAINS ANTI-TUMOR CELL ACTIVITY OF MYELOID CELLS IN GLIOBLASTOMA by Sun, Rui, Khan, Saad, Luo, Jingqin, McCornack, Colin, Chen, Yun, Jiang, Haowu, Mao, Diane D, Yang, Alicia, Liu, Qin, Petti, Allegra, Holtzman, David, Kim, Albert

“…Abstract Tumor-associated myeloid cell populations occupy a major part of the glioblastoma (GBM) tumor microenvironment (TME). The prevailing view is that…”
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