Search Results - "Mao, Decai"
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A post-ingestive amino acid sensor promotes food consumption in Drosophila
Published in Cell research (01-10-2018)“…Adequate protein intake is crucial for the survival and well-being of animals. How animals assess prospective protein sources and ensure dietary amino acid…”
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2
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2013)“…The ability to engineer genomes in a specific, systematic, and cost-effective way is critical for functional genomic studies. Recent advances using the…”
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3
Enhanced Specificity and Efficiency of the CRISPR/Cas9 System with Optimized sgRNA Parameters in Drosophila
Published in Cell reports (Cambridge) (06-11-2014)“…The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies in Drosophila melanogaster. However, single-guide RNA (sgRNA)…”
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4
Role of Hakai in m6A modification pathway in Drosophila
Published in Nature communications (12-04-2021)“…N6-methyladenosine (m 6 A), the most abundant internal modification in eukaryotic mRNA, is installed by a multi-component writer complex; however, the exact…”
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5
An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila
Published in Nature communications (08-10-2018)“…Being relatively simple and practical, Drosophila transgenic RNAi is the technique of top priority choice to quickly study genes with pleiotropic functions…”
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6
Katanin p60-like 1 sculpts the cytoskeleton in mechanosensory cilia
Published in The Journal of cell biology (04-01-2021)“…Mechanoreceptor cells develop a specialized cytoskeleton that plays structural and sensory roles at the site of mechanotransduction. However, little is known…”
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7
Spectraplakin Shot Maintains Perinuclear Microtubule Organization in Drosophila Polyploid Cells
Published in Developmental cell (03-06-2019)“…Polyploid cells endoreplicate their DNA through a modified cell cycle that skips mitosis as part of their differentiation programs. Upon cell-cycle exit and…”
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8
The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking
Published in Development (Cambridge) (28-06-2019)“…The niche controls stem cell self-renewal and differentiation in animal tissues. Although the exocyst is known to be important for protein membrane trafficking…”
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9
Histone H1 defect in escort cells triggers germline tumor in Drosophila ovary
Published in Developmental biology (01-04-2017)“…Drosophila ovary is recognized as one of the best model systems to study stem cell biology in vivo. We had previously identified an autonomous role of the…”
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10
Enhanced Efficiency of flySAM by Optimization of sgRNA Parameters in Drosophila
Published in G3 : genes - genomes - genetics (01-12-2020)“…The flySAM/CRISPRa system has recently emerged as a powerful tool for gain-of-function studies in This system includes Gal4/UAS-driven dCas9 activators and U6…”
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11
pNP Transgenic RNAi System Manual in Drosophila
Published in Bio-protocol (05-02-2019)“…Much of our knowledge about the mechanisms underlying biological processes relies on genetic approaches, whereby gene activity is reduced and the phenotypic…”
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12
Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-2018)“…CRISPR/Cas9-based transcriptional activation (CRISPRa) has recently emerged as a powerful and scalable technique for systematic overexpression genetic analysis…”
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13
HP1c regulates development and gut homeostasis by suppressing Notch signaling through Su(H)
Published in EMBO reports (07-04-2021)“…Notch signaling and epigenetic factors are known to play critical roles in regulating tissue homeostasis in most multicellular organisms, but how Notch…”
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14
Role of Hakai in m 6 A modification pathway in Drosophila
Published in Nature communications (12-04-2021)“…N6-methyladenosine (m A), the most abundant internal modification in eukaryotic mRNA, is installed by a multi-component writer complex; however, the exact…”
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15
Performance of the Cas9 nickase system in Drosophila melanogaster
Published in G3 : genes - genomes - genetics (01-10-2014)“…Recent studies of the Cas9/sgRNA system in Drosophila melanogaster genome editing have opened new opportunities to generate site-specific mutant collections in…”
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