Search Results - "Manzoni, Martina"
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1
Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity
Published in Leukemia (01-09-2018)“…The biological role and therapeutic potential of long non-coding RNAs (lncRNAs) in multiple myeloma (MM) are still to be investigated. Here, we studied the…”
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2
Circulating tumor DNA reveals genetics, clonal evolution, and residual disease in classical Hodgkin lymphoma
Published in Blood (31-05-2018)“…The rarity of neoplastic cells in the biopsy imposes major technical hurdles that have so far limited genomic studies in classical Hodgkin lymphoma (cHL). By…”
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3
Unveiling the interplay between rational, psychological and functional factors in continuous glucose monitoring early adoption: Novel evidence from the Dexcom ONE case in Italy
Published in BMC health services research (18-06-2024)“…The escalating prevalence of diabetes, with its multifaceted complications, poses a pressing challenge for healthcare systems globally. In response, the advent…”
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4
Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma
Published in Oncotarget (22-03-2016)“…Although many efforts have recently contributed to improve our knowledge of molecular pathogenesis of multiple myeloma (MM), the role and significance of long…”
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5
Long non-coding RNA NEAT1 shows high expression unrelated to molecular features and clinical outcome in multiple myeloma
Published in Haematologica (Roma) (01-02-2019)Get full text
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6
Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma
Published in Clinical cancer research (01-12-2021)“…Multiple myeloma is a biologically heterogenous plasma-cell disorder. In this study, we aimed at dissecting the functional impact on transcriptome of gene…”
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7
Circulating tumor DNA as a liquid biopsy in plasma cell dyscrasias
Published in Haematologica (Roma) (01-06-2018)Get full text
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8
Psychosocial resources and psychopathology among persons with neuromuscular disorders during the COVID-19 pandemic
Published in BMC Psychology (29-04-2024)“…The COVID-19 pandemic substantially affected the lives of persons with inherited neuromuscular disorders (INMD), causing disruption in clinical and support…”
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9
Expanding the repertoire of miRNAs and miRNA-offset RNAs expressed in multiple myeloma by small RNA deep sequencing
Published in Blood cancer journal (New York) (19-02-2019)“…Microarray analysis of the multiple myeloma (MM) miRNome has unraveled the differential expression of miRNAs in cytogenetic subgroups, their involvement in the…”
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10
Limits and Applications of Genomic Analysis of Circulating Tumor DNA as a Liquid Biopsy in Asymptomatic Forms of Multiple Myeloma
Published in HemaSphere (01-08-2020)“…Supplemental Digital Content is available in the text…”
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11
Whole-Blood Transcriptional Profiles Enable Early Prediction of the Presence of Coronary Atherosclerosis and High-Risk Plaque Features at Coronary CT Angiography
Published in Biomedicines (02-06-2022)“…Existing tools to estimate cardiovascular (CV) risk have sub-optimal predictive capacities. In this setting, non-invasive imaging techniques and omics…”
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12
Therapeutic activation of G protein-coupled estrogen receptor 1 in Waldenström Macroglobulinemia
Published in Experimental hematology & oncology (12-09-2022)“…Abstract Activating G protein-coupled estrogen receptor 1 (GPER1) is an attractive therapeutic strategy for treating a variety of human diseases including…”
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13
Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia
Published in PloS one (18-03-2015)“…IGF1R is emerging as an important gene in the pathogenesis of many solid and haematological cancers and its over-expression has been reported as frequently…”
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14
Eye movement desensitization and reprocessing: The state of the art of efficacy in children and adolescent with post traumatic stress disorder
Published in Journal of affective disorders (01-03-2021)“…•This study summarizes the research evidences about the efficacy of EMDR in children and adolescent with post traumatic stress Disorders, anxiety and…”
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15
A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma
Published in Scientific reports (26-04-2018)“…Multiple myeloma (MM) is a clonal proliferation of bone marrow plasma cells characterized by highly heterogeneous genetic background and clinical course, whose…”
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16
Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma
Published in Leukemia (01-01-2020)“…The biological role and therapeutic potential of long non-coding RNAs (lncRNAs) in multiple myeloma (MM) are still open questions. Herein, we investigated the…”
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17
Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation
Published in Circulation research (22-07-2022)“…Conversion of cardiac stromal cells into myofibroblasts is typically associated with hypoxia conditions, metabolic insults, and/or inflammation, all of which…”
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18
Exploring telediagnostic procedures in child neuropsychiatry: addressing ADHD diagnosis and autism symptoms through supervised machine learning
Published in European child & adolescent psychiatry (01-01-2024)“…Recently, there has been an increase in telemedicine applied to child neuropsychiatry, such as the use of online platforms to collect remotely case histories…”
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Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92
Published in Blood (06-09-2018)“…The microRNA (miRNA) cluster miR-17-92 is oncogenic and represents a valuable therapeutic target in c-MYC (MYC)–driven malignancies. Here, we developed novel…”
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20
Compendium of FAM46C gene mutations in plasma cell dyscrasias
Published in British journal of haematology (01-08-2016)Get full text
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