Search Results - "Manzoni, L"

Integrin-Targeted Peptide- and Peptidomimetic-Drug Conjugates for the Treatment of Tumors by Arosio, D, Manzoni, L, Corno, C, Perego, P

“…Integrins are heterodimeric cell surface receptors that mediate cell-cell and cell-extracellular matrix adhesion. These molecules play a role in processes such…”
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Integrin-mediated drug delivery in cancer and cardiovascular diseases with peptide-functionalized nanoparticles by Arosio, D, Casagrande, C, Manzoni, L

“…In recent years progress has been speeding in studies of cell-cell interaction governed by adhesion molecules, and in particular by integrins and their ligands…”
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A tailored machine learning approach for mortality prediction in severe COVID-19 treated with glucocorticoids by Salton, F., Rispoli, M., Confalonieri, P., De Nes, A., Spagnol, E., Salotti, A., Ruaro, B., Harari, S., Rocca, A., A. d'Onofrio, Manzoni, L., Confalonieri, M.

“…BACKGROUND The impact of severe COVID-19 pneumonia on healthcare systems highlighted the need for accurate predictions to improve patient outcomes. Despite the…”
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Design, synthesis and biological evaluation of novel dimeric and tetrameric cRGD-paclitaxel conjugates for integrin-assisted drug delivery by Bianchi, A, Arosio, D, Perego, P, De Cesare, M, Carenini, N, Zaffaroni, N, De Matteo, M, Manzoni, L

“…Integrins are associated with tumour cell survival and progression, and their expression has been shown to be increased in tumours. Thus, four novel conjugates…”
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Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib by Lecis, D, Drago, C, Manzoni, L, Seneci, P, Scolastico, C, Mastrangelo, E, Bolognesi, M, Anichini, A, Kashkar, H, Walczak, H, Delia, D

“…Background: XIAP (X-linked inhibitor of apoptosis protein) is an anti-apoptotic protein exerting its activity by binding and suppressing caspases. As XIAP is…”
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New potent αvβ3 integrin ligands based on azabicycloalkane (γ,α)-dipeptide mimics by Pilkington-Miksa, M, Araldi, E M V, Arosio, D, Belvisi, L, Civera, M, Manzoni, L

“…We have designed a new synthetic strategy for the preparation of a new class of cyclic RGD integrin ligands in which the azabicycloalkane scaffold can be…”
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Severe brain injured patients’ families: Problems and needs after discharge. A study carried out in the north of Italy by Salvi, G.P, Quarenghi, A, Manzoni, L, Smirni, L, Inzaghi, M.G, Simonini, M, Ancona, E

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Stereoselective Synthesis of Conformationally Constrained Cyclohexanediols:  A Set of Molecular Scaffolds for the Synthesis of Glycomimetics by Bernardi, Anna, Arosio, Daniela, Manzoni, Leonardo, Micheli, Fabrizio, Pasquarello, Alessandra, Seneci, Pierfausto

“…The practical, stereoselective synthesis of the three diastereoisomeric 1,2-trans-dicarboxy-4,5-cyclohexanediols 1−3 (DCCHDs) is described, starting from a…”
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PPCon 1.0: Biogeochemical-Argo profile prediction with 1D convolutional networks by Pietropolli, Gloria, Manzoni, Luca, Cossarini, Gianpiero

“…Effective observation of the ocean is vital for studying and assessing the state and evolution of the marine ecosystem and for evaluating the impact of human…”
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Effect of trunk girdling on fruit production, quality and storability in A. chinensis var. chinensis ‘Zesy002’ in Italy by Donati, I., Onofrietti, C., Raule, N., Cellini, A., Manzoni, L., Spinelli, F., Xylogiannis, E.

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Rapid synthesis of oligosaccharides using an anomeric fluorous silyl protecting group by Manzoni, Leonardo

“…A fluorous silyl ether tag as protecting group at the anomeric position of sugar acceptors allows rapid synthesis of oligosaccharides by reducing the…”
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Combining neural networks and data assimilation to enhance the spatial impact of Argo floats in the Copernicus Mediterranean biogeochemical model by Amadio, Carolina, Teruzzi, Anna, Pietropolli, Gloria, Manzoni, Luca, Coidessa, Gianluca, Cossarini, Gianpiero

“…Biogeochemical-Argo (BGC-Argo) float profiles provide substantial information on key vertical biogeochemical dynamics and have been successfully integrated in…”
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Follow-up of 53 Alzheimer patients with the MODA (Milan Overall Dementia Assessment) by Capitani, E., Manzoni, L, Spinnler, H.

“…Fifty‐three patients affected by Alzheimer's disease entered a longitudinal survey aimed at studying which factors influence the rate of progression, assessed…”
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A theory of the Casimir effect for compact regions by Manzoni, L.A., Wreszinski, W.F.

“…We develop a mathematically precise framework for the Casimir effect. Our working hypothesis, verified in the case of parallel plates, is that only the…”
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Variational Autoencoder for Early Stress Detection in Smart Agriculture: A Pilot Study by Zancanaro, Alberto, Cisotto, Giulia, Tegegn, Dagmawi Delelegn, Manzoni, Sara L., Reguzzoni, Ivan, Lotti, Edoardo, Zoppis, Italo

“…The digitalization of the agrifood market is increasingly demanding for new technologies to support its transition towards smart agriculture, a sustainable…”
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Froc:  A New Fluorous Protective Group for Peptide and Oligosaccharide Synthesis by Manzoni, Leonardo, Castelli, Riccardo

“…The synthesis of a new fluorous protecting group, Froc, is described. This new fluorous tag has been used in peptide and carbohydrate synthesis by our group…”
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Follow-up of 53 Alzheimer patients with the MODA (Milan Overall Dementia Assessment) by Capitani, E, Manzoni, L, Spinnler, H

“…Fifty-three patients affected by Alzheimer's disease entered a longitudinal survey aimed at studying which factors influence the rate of progression, assessed…”
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Follow-up of 53 Alzheimer patients with the MODA (Milan Overall Dementia Assessment) by Capitani, E, Manzoni, L, Spinnler, H

“…Fifty-three patients affected by Alzheimer's disease entered a longitudinal survey aimed at studying which factors influence the rate of progression, assessed…”
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Radiative corrections for the gauged Thirring model in causal perturbation theory by Manzoni, L.A., Pimentel, B.M., Tomazelli, J.L.

“…We evaluate the one-loop fermion self-energy for the gauged Thirring model in (2+1) dimensions, with one massive fermion flavor. We do this in the framework of…”
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Causal theory for the gauged Thirring model by Manzoni, L.A., Pimentel, B.M., Tomazelli, J.L.

“…We consider the (2+1)-dimensional massive Thirring model as a gauge theory, with one-fermion flavor, in the framework of the causal perturbation theory and…”
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