Pre-Lens Tear Meniscus Height, Lipid Layer Pattern and Non-Invasive Break-Up Time Short-Term Changes with a Water Gradient Silicone Hydrogel Contact Lens

Pre-Lens Tear Meniscus Height, Lipid Layer Pattern and Non-Invasive Break-Up Time Short-Term Changes with a Water Gradient Silicone Hydrogel Contact Lens

To evaluate pre-lens tear film volume, stability and lipid interferometry patterns with a silicone hydrogel water content contact lens, a novel, noninvasive, ocular-surface-analyzer technology was used. A prospective, longitudinal, single-center, self-control study was performed in daily or monthly...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Vol. 12; no. 11; p. 1710
Main Authors: Capote-Puente, Raúl, Bautista-Llamas, María-José, Manzoni, Caterina, Sánchez-González, José-María
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 26-10-2022
MDPI
Subjects:
Analysis
Astigmatism
Blinking
Colloids
Contact angle
contact lens
Contact lenses
Cornea
Desiccation
Design
Design and construction
Ethylenediaminetetraacetic acid
Evaluation
Eye diseases
Eyelid
Health aspects
Hydrogels
Injuries
Interferometry
Knee
lipid pattern
Lipids
Materials
Mean
Moisture content
non-invasive break-up time
Optometry
pre-lens tear film
Quality assessment
Questionnaires
Signs and symptoms
Silicones
Stability analysis
Statistical analysis
Surface analyzers
Technology assessment
Thickness
Water content
Spain
United States > US
Italy
pre-lens tear film
lipid pattern
non-invasive break-up time
contact lens
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Description
Summary:To evaluate pre-lens tear film volume, stability and lipid interferometry patterns with a silicone hydrogel water content contact lens, a novel, noninvasive, ocular-surface-analyzer technology was used. A prospective, longitudinal, single-center, self-control study was performed in daily or monthly replacement silicone hydrogel contact lens wearers. A tear film analysis was achieved with the Integrated Clinical Platform (ICP) Ocular Surface Analyzer (OSA) from SBM System. The subjects were reassessed, with the contact lens, after 30 min of wearing to quantify the volume, stability and lipid pattern of the short-term pre-lens tear film. Lipid layer thickness decreased from 2.05 ± 1.53 to 1.90 ± 1.73 Guillon patterns (p = 0.23). First pre-lens NIBUT decreased from 5.03 ± 1.04 to 4.63 ± 0.89 s (p = 0.01). Mean pre-lens NIBUT significantly increased from 15.19 ± 9.54 to 21.27 ± 11.97 s (p < 0.01). Lid opening time significantly increased from 26.36 ± 19.72 to 38.58 ± 21.78 s (p < 0.01). The silicone hydrogel contact lens with water gradient technology significantly increased the mean pre-lens NIBUT and lid opening time. Lehfilcon A suggested an improvement in contact lens wearers with tear film instability or decreased subjective symptoms of dry eye disease.
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content type line 23
ISSN:2075-1729
2075-1729
DOI:10.3390/life12111710