Search Results - "Manzi, John"

A balance between membrane elasticity and polymerization energy sets the shape of spherical clathrin coats by Saleem, Mohammed, Morlot, Sandrine, Hohendahl, Annika, Manzi, John, Lenz, Martin, Roux, Aurélien

“…In endocytosis, scaffolding is one of the mechanisms to create membrane curvature by moulding the membrane into the spherical shape of the clathrin cage…”
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IRSp53 senses negative membrane curvature and phase separates along membrane tubules by Prévost, Coline, Zhao, Hongxia, Manzi, John, Lemichez, Emmanuel, Lappalainen, Pekka, Callan-Jones, Andrew, Bassereau, Patricia

“…BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the…”
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Nature of curvature coupling of amphiphysin with membranes depends on its bound density by Sorre, Benoît, Callan-Jones, Andrew, Manzi, John, Goud, Bruno, Prost, Jacques, Bassereau, Patricia, Roux, Aurélien

“…Cells are populated by a vast array of membrane-binding proteins that execute critical functions. Functions, like signaling and intracellular transport,…”
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Actin dynamics drive cell-like membrane deformation by Simon, Camille, Kusters, Rémy, Caorsi, Valentina, Allard, Antoine, Abou-Ghali, Majdouline, Manzi, John, Di Cicco, Aurélie, Lévy, Daniel, Lenz, Martin, Joanny, Jean-François, Campillo, Clément, Plastino, Julie, Sens, Pierre, Sykes, Cécile

“…Cell membrane deformations are crucial for proper cell function. Specialized protein assemblies initiate inward or outward membrane deformations that the cell…”
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Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction by Morlot, Sandrine, Galli, Valentina, Klein, Marius, Chiaruttini, Nicolas, Manzi, John, Humbert, Frédéric, Dinis, Luis, Lenz, Martin, Cappello, Giovanni, Roux, Aurélien

“…The GTPase dynamin polymerizes into a helical coat that constricts membrane necks of endocytic pits to promote their fission. However, the dynamin mechanism is…”
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Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites by de la Mora, Eugenio, Dezi, Manuela, Di Cicco, Aurélie, Bigay, Joëlle, Gautier, Romain, Manzi, John, Polidori, Joël, Castaño-Díez, Daniel, Mesmin, Bruno, Antonny, Bruno, Lévy, Daniel

“…Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Structural…”
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Mechanics of Biomimetic Liposomes Encapsulating an Actin Shell by Guevorkian, Karine, Manzi, John, Pontani, Léa-Lætitia, Brochard-Wyart, Françoise, Sykes, Cécile

“…Cell-shape changes are insured by a thin, dynamic, cortical layer of cytoskeleton underneath the plasma membrane. How this thin cortical structure impacts the…”
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WAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly by Havrylenko, Svitlana, Noguera, Philippe, Abou-Ghali, Majdouline, Manzi, John, Faqir, Fahima, Lamora, Audrey, Guérin, Christophe, Blanchoin, Laurent, Plastino, Julie

“…The WAVE complex is the main activator of the Arp2/3 complex for actin filament nucleation and assembly in the lamellipodia of moving cells. Other important…”
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Actin polymerization or myosin contraction: two ways to build up cortical tension for symmetry breaking by Carvalho, Kevin, Lemière, Joël, Faqir, Fahima, Manzi, John, Blanchoin, Laurent, Plastino, Julie, Betz, Timo, Sykes, Cécile

“…Cells use complex biochemical pathways to drive shape changes for polarization and movement. One of these pathways is the self-assembly of actin filaments and…”
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Nanoplasmonic Sensor Detects Preferential Binding of IRSp53 to Negative Membrane Curvature by Emilsson, Gustav, Röder, Evelyn, Malekian, Bita, Xiong, Kunli, Manzi, John, Tsai, Feng-Ching, Cho, Nam-Joon, Bally, Marta, Dahlin, Andreas

“…Biosensors based on plasmonic nanostructures are widely used in various applications and benefit from numerous operational advantages. One type of application…”
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Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53 by Inamdar, Kaushik, Tsai, Feng-Ching, Dibsy, Rayane, de Poret, Aurore, Manzi, John, Merida, Peggy, Muller, Remi, Lappalainen, Pekka, Roingeard, Philippe, Mak, Johnson, Bassereau, Patricia, Favard, Cyril, Muriaux, Delphine

“…During HIV-1 particle formation, the requisite plasma membrane curvature is thought to be solely driven by the retroviral Gag protein. Here, we reveal that the…”
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Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner by Tsai, Feng-Ching, Bertin, Aurelie, Bousquet, Hugo, Manzi, John, Senju, Yosuke, Tsai, Meng-Chen, Picas, Laura, Miserey-Lenkei, Stephanie, Lappalainen, Pekka, Lemichez, Emmanuel, Coudrier, Evelyne, Bassereau, Patricia

“…One challenge in cell biology is to decipher the biophysical mechanisms governing protein enrichment on curved membranes and the resulting membrane…”
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Functional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles by Aimon, Sophie, Manzi, John, Schmidt, Daniel, Poveda Larrosa, Jose Antonio, Bassereau, Patricia, Toombes, Gilman E S

“…Voltage-gated ion channels are key players in cellular excitability. Recent studies suggest that their behavior can depend strongly on the membrane lipid…”
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How actin network dynamics control the onset of actin-based motility by Kawska, Agnieszka, Carvalho, Kévin, Manzi, John, Boujemaa-Paterski, Rajaa, Blanchoin, Laurent, Martiel, Jean-Louis, Sykes, Cécile

“…Cells use their dynamic actin network to control their mechanics and motility. These networks are made of branched actin filaments generated by the Arp2/3…”
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Activated I-BAR IRSp53 clustering controls the formation of VASP-actin-based membrane protrusions by Tsai, Feng-Ching, Henderson, J Michael, Jarin, Zack, Kremneva, Elena, Senju, Yosuke, Pernier, Julien, Mikhajlov, Oleg, Manzi, John, Kogan, Konstantin, Le Clainche, Christophe, Voth, Gregory A, Lappalainen, Pekka, Bassereau, Patricia

“…Filopodia are actin-rich membrane protrusions essential for cell morphogenesis, motility, and cancer invasion. How cells control filopodium initiation on the…”
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SNX9: An Unconventional Bar Domain Protein? by Tsai, Feng-Ching, Arumugam, Senthil, Manzi, John, Bassereau, Patricia M.

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Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells by Liße, Domenik, Monzel, Cornelia, Vicario, Chiara, Manzi, John, Maurin, Isabelle, Coppey, Mathieu, Piehler, Jacob, Dahan, Maxime

“…Magnetogenetics is emerging as a novel approach for remote‐controlled manipulation of cellular functions in tissues and organisms with high spatial and…”
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Dynamics of cell adhesion on fluid substrates by Mikhajlov, Oleg, Di Federico, Fahima, Manzi, John, Tabarin, Fanny, van Nhieu, Guy Tran, Bassereau, Patricia M.

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Conformation-dependent diffusion properties of a transmembrane protein by Regmi, Raju, Gressier, Titouan, Chauvin, Brieuc, Damm, Alicia, Manzi, John, Dezi, Manuela, Levy, Daniel, Bassereau, Patricia M.

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Modeling Detergent Organization around Aquaporin-0 Using Small-Angle X-ray Scattering by Berthaud, Alice, Manzi, John, Pérez, Javier, Mangenot, Stéphanie

“…Solubilization of integral membrane proteins in aqueous solutions requires the presence of amphiphilic molecules like detergents. The transmembrane region of…”
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