Search Results - "Manzanillo, Paolo S."

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway by Watson, Robert O., Manzanillo, Paolo S., Cox, Jeffery S.

“…Eukaryotic cells sterilize the cytosol by using autophagy to route invading bacterial pathogens to the lysosome. During macrophage infection with Mycobacterium…”
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Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages by Manzanillo, Paolo S., Shiloh, Michael U., Portnoy, Daniel A., Cox, Jeffery S.

“…Cytosolic bacterial pathogens activate the cytosolic surveillance pathway (CSP) and induce innate immune responses, but how the host detects vacuolar pathogens…”
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens by Manzanillo, Paolo S., Ayres, Janelle S., Watson, Robert O., Collins, Angela C., Souza, Gianne, Rae, Chris S., Schneider, David S., Nakamura, Ken, Shiloh, Michael U., Cox, Jeffery S.

“…Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defence mechanism against invading microbes, including the…”
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Salmonella Require the Fatty Acid Regulator PPARδ for the Establishment of a Metabolic Environment Essential for Long-Term Persistence by Eisele, Nicholas A., Ruby, Thomas, Jacobson, Amanda, Manzanillo, Paolo S., Cox, Jeffery S., Lam, Lilian, Mukundan, Lata, Chawla, Ajay, Monack, Denise M.

“…Host-adapted Salmonella strains are responsible for a number of disease manifestations in mammals, including an asymptomatic chronic infection in which…”
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Correction: Crystal structures of human procathepsin H by Hao, Yue, Purtha, Whitney E, Cortesio, Christa, Rui, Huan, Gu, Yan, Chen, Hao, Sickmier, E Allen, Manzanillo, Paolo S, Huang, Xin

“…[This corrects the article DOI: 10.1371/journal.pone.0200374.]…”
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cor, a novel carbon monoxide resistance gene, is essential for Mycobacterium tuberculosis pathogenesis by Zacharia, Vineetha M, Manzanillo, Paolo S, Nair, Vidhya R, Marciano, Denise K, Kinch, Lisa N, Grishin, Nick V, Cox, Jeffery S, Shiloh, Michael U

“…Tuberculosis, caused by Mycobacterium tuberculosis, remains a devastating human infectious disease, causing two million deaths annually. We previously…”
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STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets by Bhatt, Dev, Kang, Boxi, Sawant, Deepali, Zheng, Liangtao, Perez, Kristy, Huang, Zhiyu, Sekirov, Laura, Wolak, Dan, Huang, Julie Y, Liu, Xian, DeVoss, Jason, Manzanillo, Paolo S, Pierce, Nathan, Zhang, Zemin, Symons, Antony, Ouyang, Wenjun

“…Single-cell RNA sequencing is a powerful tool to examine cellular heterogeneity, novel markers and target genes, and therapeutic mechanisms in human cancers…”
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Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells by Alumasa, John N, Manzanillo, Paolo S, Peterson, Nicholas D, Lundrigan, Tricia, Baughn, Anthony D, Cox, Jeffery S, Keiler, Kenneth C

“…The emergence of Mycobacterium tuberculosis (MTB) strains that are resistant to most or all available antibiotics has created a severe problem for treating…”
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens by Manzanillo, Paolo S, Ayres, Janelle S, Watson, Robert O, Collins, Angela C, Souza, Gianne, Rae, Chris S, Schneider, David S, Nakamura, Ken, Shiloh, Michael U, Cox, Jeffery S

“…Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defence mechanism against invading microbes, including the…”
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PARKIN ubiquitin ligase mediates resistance to intracellular pathogens by Manzanillo, Paolo S., Ayres, Janelle S., Watson, Robert O., Collins, Angela C., Souza, Gianne, Rae, Chris S., Schneider, David S., Nakamura, Ken, Shiloh, Michael U., Cox, Jeffery S.

“…Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defense mechanism against invading microbes, including the…”
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italic toggle="yes">cor /italic>, a Novel Carbon Monoxide Resistance Gene, Is Essential for Mycobacterium tuberculosis Pathogenesis by Vineetha M. Zacharia, Paolo S. Manzanillo, Vidhya R. Nair, Denise K. Marciano, Lisa N. Kinch, Nick V. Grishin, Jeffery S. Cox, Michael U. Shiloh

“…ABSTRACT Tuberculosis, caused by Mycobacterium tuberculosis, remains a devastating human infectious disease, causing two million deaths annually. We previously…”
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