Search Results - "Manwar Hussain, Muhammad Ramzan"

Charge and Polarity Preferences for N -Glycosylation: A Genome-Wide In Silico Study and Its Implications Regarding Constitutive Proliferation and Adhesion of Carcinoma Cells by Manwar Hussain, Muhammad Ramzan, Iqbal, Zeeshan, Qazi, Wajahat M, Hoessli, Daniel C

“…The structural and functional diversity of the human proteome is mediated by - and linked glycosylations that define the individual properties of extracellular…”
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Physiological significance of Fuc and Sialic acid containing glycans in the body by Hussain, Muhammad Ramzan Manwar, Din, Nasirud, Hassan, Mukhtarul, Razaq, Abdul, Iqbal, Zeeshan

“…Complex biomolecular machinery carrying diverse glycan chains are involved in a wide range of physiological activities including blood group determination,…”
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First Comprehensive In Silico Analysis of the Functional and Structural Consequences of SNPs in Human GalNAc-T1 Gene by Ali Mohamoud, Hussein Sheikh, Manwar Hussain, Muhammad Ramzan, El-Harouni, Ashraf A., Shaik, Noor Ahmad, Qasmi, Zaheer Ulhaq, Merican, Amir Feisal, Baig, Mukhtiar, Anwar, Yasir, Asfour, Hani, Bundajji, Nabil S., al-Aama, Jumana Yousuf

“…GalNAc-T1, a key candidate of GalNac-transferases genes family that is involved in mucin-type O-linked glycosylation pathway, is expressed in most biological…”
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From genes to health - challenges and opportunities by Manwar Hussain, Muhammad Ramzan, Khan, Asifullah, Ali Mohamoud, Hussein Sheikh

“…In genome science, the advancement in high-throughput sequencing technologies and bioinformatics analysis is facilitating the better understanding of Mendelian…”
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The role of Galactose in human health and disease by Manwar Hussain, Muhammad Ramzan, Hassan, Mukhtarul, Shaik, Noor Ahmad, Iqbal, Zeeshan

“…According to the universal biological findings, cellular bodies are covered with an intense coating of glycans. Diversity of glycan chains, linked to lipids…”
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N-acetylgalactosaminyltransferases in cancer by Hussain, Muhammad Ramzan Manwar, Hoessli, Daniel C, Fang, Min

“…Aberrant mucin-type O-glycosylation by glycosyltransferases is a well-described hallmark of many cancers and is also associated with additional non-cancerous…”
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In silico analysis of Single Nucleotide Polymorphisms (SNPs) in human BRAF gene by Hussain, Muhammad Ramzan Manwar, Shaik, Noor Ahmad, Al-Aama, Jumana Yousuf, Asfour, Hani Z., Subhani Khan, Fatima, Masoodi, Tariq Ahmad, Khan, Muhammad Akhtar, Shaik, Nazia Sultana

“…BRAF gene mutations are frequently seen in both inherited and somatic diseases. However, the harmful mutations for BRAF gene have not been predicted in silico…”
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BRAF gene: From human cancers to developmental syndromes by Hussain, Muhammad Ramzan Manwar, Baig, Mukhtiar, Mohamoud, Hussein Sheik Ali, Ulhaq, Zaheer, Hoessli, Daniel C., Khogeer, Ghaidaa Siraj, Al-Sayed, Ranem Radwan, Al-Aama, Jumana Yousuf

“…The BRAF gene encodes for a serine/threonine protein kinase that participates in the MAPK/ERK signalling pathway and plays a vital role in cancers and…”
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Clinically Significant Missense Variants in Human GALNT3, GALNT8, GALNT12, and GALNT13 Genes: Intriguing In Silico Findings by Hussain, Muhammad Ramzan M., Nasir, Jamal, Al-Aama, Jumana Yousuf

“…ABSTRACT Aberrant glycosylation by N‐acetylgalactosaminyl transferases (GALNTs) is a well‐described pathological alteration that is widespread in hereditary…”
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The Microbial Pathology of Neu5Ac and Gal Epitopes by Hussain, Muhammad Ramzan Manwar, Asfour, Hani, Yasir, Muhammad, Khan, Asifullah, Mohamoud, Hussein Sheikh Ali, Al-Aama, Jumana Y.

“…Glycans play a vital role in modulating many physiological and pathological phenomena of microbes and humans, such as bacterial adhesion, colonization,…”
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Role of Gal and GalNAc containing glycans in various physiological processes by Hussain, Muhammad Ramzan Manwar, Hassan, Mukhtarul, Afzal, Imran, Afzal, Ayyaz

“…Glycoconjugates are involved in the vital physiological functions including blood group determination, cancer recognition, protein stabilization, sperm-egg…”
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