Search Results - "Manuvera, V A"

Inhibition of Chlamydial Infection by CRISPR/Cas9-SAM Mediated Enhancement of Human Peptidoglycan Recognition Proteins Gene Expression in HeLa Cells by Bobrovsky, P. A., Moroz, V. D., Lavrenova, V. N., Manuvera, V. A., Lazarev, V. N.

“…The global problem of emerging resistance of microorganisms to antibiotics makes the search for new natural substances with antibacterial properties relevant…”
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Specific Activation of the Expression of Growth Factor Genes in Expi293F Human Cells Using CRISPR/Cas9-SAM Technology Increases Their Proliferation by Bobrovsky, P A, Grafskaia, E N, Kharlampieva, D D, Manuvera, V A, Lazarev, V N

“…Human cell lines play an important role in biotechnology and pharmacology. For them to grow, they need complex nutrient media containing signaling proteins -…”
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Oligomerization of the IHF Protein in the Presence of Metal Cations by Gordienko, A. M., Dadinova, L. A., Petoukhov, M. V., Mozhaev, A. A., Manuvera, V. A., Lazarev, V. N., Shtykova, E. V.

“…The oligomeric state of the nucleoid-associated protein IHF (integration host factor) plays a significant role in the organization and compaction of the…”
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Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens by Grafskaia, E.N., Nadezhdin, K.D., Talyzina, I.A., Polina, N.F., Podgorny, O.V., Pavlova, E.R., Bashkirov, P.V., Kharlampieva, D.D., Bobrovsky, P.A., Latsis, I.A., Manuvera, V.A., Babenko, V.V., Trukhan, V.M., Arseniev, A.S., Klinov, D.V., Lazarev, V.N.

“…The rise of antibiotic resistance has necessitated the development of alternative strategies for the treatment of infectious diseases. Antimicrobial peptides…”
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Effects of signal peptide primary structure on efficiency of recombinant Staphylococcus aureus pro-enterotoxin A transmembrane translocation in E. coli cells by Manuvera, V. A, Mordkovich, N. N, Veiko, V. P, Debabov, V. G

“…Enterotoxin A containing various leader sequences have been obtained by site-driven mutagenesis. Some of them were capable of providing the translocation of…”
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Binding site of MraZ transcription factor in Mollicutes by Fisunov, G.Y., Evsyutina, D.V., Semashko, T.A., Arzamasov, A.A., Manuvera, V.A., Letarov, A.V., Govorun, V.M.

“…Mollicutes (mycoplasmas) feature a significant loss of known regulators of gene expression. Here, we identified the recognition site of the MraZ-family…”
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Role of isopeptidolysis in the process of thrombolysis by Baskova, I.P., Kalabushev, S.N., Akhaev, D.N., Bobrovsky, P.A., Manuvera, V.A., Lazarev, V.N.

“…Known thrombolytic agents either break peptide bonds in the fibrin molecule or act as plasminogen activators, which also results in peptide bond cleavage. In…”
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Concerted action of two subunits of the functional dimer of Shewanella oneidensis MR-1 uridine phosphorylase derived from a comparison of the C212S mutant and the wild-type enzyme by Safonova, T. N., Mordkovich, N. N., Veiko, V. P., Okorokova, N. A., Manuvera, V. A., Dorovatovskii, P. V., Popov, V. O., Polyakov, K. M.

“…Uridine phosphorylase (UP; EC 2.4.2.3), a key enzyme in the pyrimidine‐salvage pathway, catalyzes the reversible phosphorolysis of uridine to uracil and ribose…”
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Study of Structural-Functional Organization of Nucleoside Phosphorylases of Gammaproteobacteria. Special Aspects of Functioning of Uridine Phosphorylase Phosphate-Binding Site by Mordkovich, N. N., Safonova, T. N., Antipov, A. N., Manuvera, V. A., Polyakov, K. M., Okorokova, N. A., Veiko, V. P.

“…Series of mutant genes of prokaryotic uridine phosphorylases ( Shewanella oneidensis MR-1, Escherichia coli ) were constructed, and the resulting…”
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Purification and characterisation of recombinant Bacteroides fragilis toxin-2 by Kharlampieva, D.D., Manuvera, V.A., Podgorny, O.V., Kovalchuk, S.I., Pobeguts, O.V., Altukhov, I.A., Alexeev, D.G., Lazarev, V.N., Govorun, V.M.

“…Fragilysin (BFT) is metalloprotease that is secreted by enterotoxigenic Bacteroides fragilis. Studying the mechanism of BFT interaction with intestinal…”
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Recombinant small heat shock protein from Acholeplasma laidlawii increases the Escherichia coli viability in thermal stress by selective protein rescue by Kayumov, A. R., Bogachev, M. I., Manuvera, V. A., Lazarev, V. N., Sabantsev, A. V., Artamonova, T. O., Borchsenius, S. N., Vishnyakov, I. E.

“…In both prokaryotes and eukaryotes, the survival at temperatures considerably exceeding the optimum is supported by intense synthesis of the so-called heat…”
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Recombinant destabilase from the medicinal leech: Preparation and properties by Kurdyumov, A. S., Manuvera, V. A., Akhaev, D. N., Baskova, I. P., Lazarev, V. N.

“…The procedure for obtaining an active recombinant destabilase from the medicinal leech in Escherichia coli cells was developed. The plasmids encoding an…”
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Uridine phosphorylase from Shewanella oneidensis MR-1: Heterological expression, regulation, transcription, and properties by Mordkovich, N. N., Manuvera, V. A., Veiko, V. P., Debabov, V. G.

“…A DNA fragment containing a promoter-operator and structural parts of the uridine phosphorylase gene from Shewanella oneidensis MR-1 was cloned…”
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Physicochemical characterization of uridine phosphorylase from Shewanella oneidensis MR-1 by Mordkovich, N. N., Safonova, T. N., Manuvera, V. A., Veiko, V. P., Polyakov, K. M., Alekseev, K. S., Mikhailov, S. N., Popov, V. O.

“…Uridine phosphorylase (UP) belongs to nucleoside phosphorylases that play an important role in nucleoside metabolism. These enzymes exhibit an elevated level…”
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Preparation and functional evaluation of RGD-modified streptavidin targeting to integrin-expressing melanoma cells by Syrkina, Marina S., Shirokov, Dmitry A., Rubtsov, Mikhail A., Kadyrova, Elena L., Veiko, Vladimir P., Manuvera, Valentin A.

“…The vertical growth stage is the most dangerous stage of melanoma and is often associated with a poor prognosis. The increased invasiveness and metastasis that…”
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Wild small mammals are the reservoir hosts of the Bartonella genus bacteria in the south of Moscow region by Markov, A P, Lopyrev, I V, Irkhin, A I, Khliap, L A, Levitskiĭ, S A, Kirillov, M Iu, Manuvera, V A, Il'ina, T S, Pokrovskaia, M S, Aleshkin, G I, Bashkirov, V N, Smirnov, G B, Kosoĭ, M

“…A total of 103 blood samples collected from wild small mammals captured in the Prioksko-Terrasny Reserve on the south of Moscow region were studied to…”
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