Search Results - "Manuilov, Anton"
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1
Quantitation of a recombinant monoclonal antibody in monkey serum by liquid chromatography–mass spectrometry
Published in Analytical biochemistry (01-07-2011)“…A method including protein A purification, limited Lys-C digestion, and mass spectrometry analysis was used in the study to quantify a recombinant monoclonal…”
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Journal Article -
2
Cell culture media supplementation of bioflavonoids for the targeted reduction of acidic species charge variants on recombinant therapeutic proteins
Published in Biotechnology progress (01-07-2015)“…Charge variants in recombinant proteins are an important series of protein modifications, whose potential role on protein stability, activity, immunogenicity,…”
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3
Comparability analysis of protein therapeutics by bottom-up LC-MS with stable isotope-tagged reference standards
Published in mAbs (01-07-2011)“…Comparability studies lie at the heart of assessments that evaluate differences amongst manufacturing processes and stability studies of protein therapeutics…”
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Journal Article -
4
New photoreactive tRNA derivatives for probing the peptidyl transferase center of the ribosome
Published in RNA (Cambridge) (01-05-2007)“…Three new photoreactive tRNA derivatives have been synthesized for use as probes of the peptidyl transferase center of the ribosome. In two of these…”
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Journal Article -
5
Differential effects of replacing Escherichia coli ribosomal protein L27 with its homologue from Aquifex aeolicus
Published in Journal of bacteriology (01-11-2001)“…The rpmA gene, which encodes 50S ribosomal subunit protein L27, was cloned from the extreme thermophile Aquifex aeolicus, and the protein was overexpressed and…”
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Journal Article -
6
New Peak Detection Performance Metrics from the MAM Consortium Interlaboratory Study
Published in Journal of the American Society for Mass Spectrometry (07-04-2021)“…The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative…”
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Journal Article -
7
Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study
Published in Journal of the American Society for Mass Spectrometry (07-09-2022)“…The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process…”
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Journal Article -
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Changes in the mutual orientation of tRNA and 23S rRNA at the peptidyl transferase center of the ribosome detected by crosslinking of a photoreactive transition-state analog
Published 01-01-2007“…Dynamic interactions between the amino acid acceptor end of tRNA and the ribosome underlie the synthesis of successive peptide bonds at the peptidyl…”
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Dissertation -
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Differential Effects of ReplacingEscherichia coli Ribosomal Protein L27 with Its Homologue from Aquifex aeolicus
Published in Journal of Bacteriology (15-11-2001)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Journal Article