Search Results - "Manuel Carreño, Juan"

Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron by Carreño, Juan Manuel, Alshammary, Hala, Tcheou, Johnstone, Singh, Gagandeep, Raskin, Ariel J., Kawabata, Hisaaki, Sominsky, Levy A., Clark, Jordan J., Adelsberg, Daniel C., Bielak, Dominika A., Gonzalez-Reiche, Ana Silvia, Dambrauskas, Nicholas, Vigdorovich, Vladimir, Srivastava, Komal, Sather, D. Noah, Sordillo, Emilia Mia, Bajic, Goran, van Bakel, Harm, Simon, Viviana, Krammer, Florian

“…The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and…”
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SARS-CoV-2 vaccination induces mucosal antibody responses in previously infected individuals by Sano, Kaori, Bhavsar, Disha, Singh, Gagandeep, Floda, Daniel, Srivastava, Komal, Gleason, Charles, Carreño, Juan Manuel, Simon, Viviana, Krammer, Florian

“…Immune responses at the respiratory mucosal interface are critical to prevent respiratory infections but it is unclear to what extent antigen specific mucosal…”
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Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses by Pardi, Norbert, Carreño, Juan Manuel, O’Dell, George, Tan, Jessica, Bajusz, Csaba, Muramatsu, Hiromi, Rijnink, Willemijn, Strohmeier, Shirin, Loganathan, Madhumathi, Bielak, Dominika, Sung, Molly M. H., Tam, Ying K., Krammer, Florian, McMahon, Meagan

“…Messenger RNA (mRNA) vaccines represent a new, effective vaccine platform with high capacity for rapid development. Generation of a universal influenza virus…”
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Permissive omicron breakthrough infections in individuals with binding or neutralizing antibodies to ancestral sars-cov-2 by Williams, Erin, Colson, Jordan, Valiathan, Ranjini, Manuel Carreño, Juan, Krammer, Florian, Hoffer, Michael, Pallikkuth, Suresh, Pahwa, Savita, Andrews, David

“…•High binding antibody titers and high surrogate neutralizing antibody activity are insufficient markers of protection from breakthrough infection in variants…”
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Sequential intrahost evolution and onward transmission of SARS-CoV-2 variants by Gonzalez-Reiche, Ana S., Alshammary, Hala, Schaefer, Sarah, Patel, Gopi, Polanco, Jose, Carreño, Juan Manuel, Amoako, Angela A., Rooker, Aria, Cognigni, Christian, Floda, Daniel, van de Guchte, Adriana, Khalil, Zain, Farrugia, Keith, Assad, Nima, Zhang, Jian, Alburquerque, Bremy, Sominsky, Levy A., Gleason, Charles, Srivastava, Komal, Sebra, Robert, Ramirez, Juan David, Banu, Radhika, Shrestha, Paras, Krammer, Florian, Paniz-Mondolfi, Alberto, Sordillo, Emilia Mia, Simon, Viviana, van Bakel, Harm

“…Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been reported in immune-compromised individuals and people undergoing…”
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Determinants of health as predictors for differential antibody responses following SARS-CoV-2 primary and booster vaccination in an at-risk, longitudinal cohort by Echeverri Tribin, Felipe, Williams, Erin, Testamarck, Valeska, Carreño, Juan Manuel, Bielak, Dominika, Yellin, Temima, Krammer, Florian, Hoffer, Michael, Pallikkuth, Suresh, Pahwa, Savita

“…Post vaccine immunity following COVID-19 mRNA vaccination may be driven by extrinsic, or controllable and intrinsic, or inherent health factors. Thus, we…”
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Monoclonal antibodies targeting the influenza virus N6 neuraminidase by Strohmeier, Shirin, Amanat, Fatima, Carreño, Juan Manuel, Krammer, Florian

“…Influenza A viruses are a diverse species that include 16 true hemagglutinin (HA) subtypes and 9 true neuraminidase (NA) subtypes. While the antigenicity of…”
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Mutations in the Hemagglutinin Stalk Domain Do Not Permit Escape from a Protective, Stalk-Based Vaccine-Induced Immune Response in the Mouse Model by Roubidoux, Ericka Kirkpatrick, Carreño, Juan Manuel, McMahon, Meagan, Jiang, Kaijun, van Bakel, Harm, Wilson, Patrick, Krammer, Florian

“…Current seasonal influenza virus vaccines target regions of the hemagglutinin (HA) head domain that undergo constant antigenic change, forcing the painstaking…”
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Safety and immunogenicity of an egg-based inactivated Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomized, placebo-controlled, phase 1/2 trial in Vietnam by Duc Dang, Anh, Dinh Vu, Thiem, Hai Vu, Ha, Thanh Ta, Van, Thi Van Pham, Anh, Thi Ngoc Dang, Mai, Van Le, Be, Huu Duong, Thai, Van Nguyen, Duoc, Lawpoolsri, Saranath, Chinwangso, Pailinrut, McLellan, Jason S., Hsieh, Ching-Lin, Garcia-Sastre, Adolfo, Palese, Peter, Sun, Weina, Martinez, Jose L., Gonzalez-Dominguez, Irene, Slamanig, Stefan, Manuel Carreño, Juan, Tcheou, Johnstone, Krammer, Florian, Raskin, Ariel, Minh Vu, Huong, Cong Tran, Thang, Mai Nguyen, Huong, Mercer, Laina D., Raghunandan, Rama, Lal, Manjari, White, Jessica A., Hjorth, Richard, Innis, Bruce L., Scharf, Rami

“…Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S is an inactivated egg-based…”
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Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site by Stadlbauer, Daniel, McMahon, Meagan, Turner, Hannah L., Zhu, Xueyong, Wan, Hongquan, Carreño, Juan Manuel, O’Dell, George, Strohmeier, Shirin, Khalil, Zain, Luksza, Marta, van Bakel, Harm, Simon, Viviana, Ellebedy, Ali H., Wilson, Ian A., Ward, Andrew B., Krammer, Florian

“…Contemporary influenza A H3N2 viruses circulating since 2016 have acquired a glycosylation site in the neuraminidase in close proximity to the enzymatic active…”
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SARS-CoV-2 serosurvey across multiple waves of the COVID-19 pandemic in New York City between 2020–2023 by Carreño, Juan Manuel, Wagner, Abram L., Monahan, Brian, Singh, Gagandeep, Floda, Daniel, Gonzalez-Reiche, Ana S., Tcheou, Johnstone, Raskin, Ariel, Bielak, Dominika, Morris, Sara, Fried, Miriam, Yellin, Temima, Sullivan, Leeba, Sordillo, Emilia Mia, Gordon, Aubree, van Bakel, Harm, Simon, Viviana, Krammer, Florian

“…Sero-monitoring provides context to the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and changes in population…”
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Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets by Halwe, Nico Joel, Hamberger, Lea, Sehl-Ewert, Julia, Mache, Christin, Schön, Jacob, Ulrich, Lorenz, Calvelage, Sten, Tönnies, Mario, Fuchs, Jonas, Bandawane, Pooja, Loganathan, Madhumathi, Abbad, Anass, Carreño, Juan Manuel, Bermúdez-González, Maria C., Simon, Viviana, Kandeil, Ahmed, El-Shesheny, Rabeh, Ali, Mohamed A., Kayali, Ghazi, Budt, Matthias, Hippenstiel, Stefan, Hocke, Andreas C., Krammer, Florian, Wolff, Thorsten, Schwemmle, Martin, Ciminski, Kevin, Hoffmann, Donata, Beer, Martin

“…Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian…”
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The post-COVID-19 population has a high prevalence of cross-reactive antibodies to spikes from all Orthocoronavirinae genera by Singh, Gagandeep, Abbad, Anass, Kleiner, Giulio, Srivastava, Komal, Gleason, Charles, Carreño, Juan Manuel, Simon, Viviana, Krammer, Florian

“…As demonstrated by severe acute respiratory syndrome coronavirus 2, coronaviruses pose a significant pandemic threat. Here, we show that coronavirus disease…”
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H1 Hemagglutinin Priming Provides Long-Lasting Heterosubtypic Immunity against H5N1 Challenge in the Mouse Model by Carreño, Juan Manuel, Strohmeier, Shirin, Kirkpatrick Roubidoux, Ericka, Hai, Rong, Palese, Peter, Krammer, Florian

“…Influenza virus infections leave a signature of immune memory that influences future responses to infections with antigenically related strains. It has been…”
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Safety and Immunogenicity Analysis of a Newcastle Disease Virus (NDV-HXP-S) Expressing the Spike Protein of SARS-CoV-2 in Sprague Dawley Rats by Tcheou, Johnstone, Raskin, Ariel, Singh, Gagandeep, Kawabata, Hisaaki, Bielak, Dominika, Sun, Weina, González-Domínguez, Irene, Sather, D Noah, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Carreño, Juan Manuel

“…Despite global vaccination efforts, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve and spread globally. Relatively high…”
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Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs by Lara-Puente, Jesús Horacio, Carreño, Juan Manuel, Sun, Weina, Suárez-Martínez, Alejandro, Ramírez-Martínez, Luis, Quezada-Monroy, Francisco, Paz-De la Rosa, Georgina, Vigueras-Moreno, Rosalía, Singh, Gagandeep, Rojas-Martínez, Oscar, Chagoya-Cortés, Héctor Elías, Sarfati-Mizrahi, David, Soto-Priante, Ernesto, López-Macías, Constantino, Krammer, Florian, Castro-Peralta, Felipa, Palese, Peter, García-Sastre, Adolfo, Lozano-Dubernard, Bernardo

“…Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were developed in record time and show excellent efficacy and effectiveness…”
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Receptor-Binding Domain (RBD) Antibodies Contribute More to SARS-CoV-2 Neutralization When Target Cells Express High Levels of ACE2 by Farrell, Ariana Ghez, Dadonaite, Bernadeta, Greaney, Allison J, Eguia, Rachel, Loes, Andrea N, Franko, Nicholas M, Logue, Jennifer, Carreño, Juan Manuel, Abbad, Anass, Chu, Helen Y, Matreyek, Kenneth A, Bloom, Jesse D

“…Neutralization assays are experimental surrogates for the effectiveness of infection- or vaccine-elicited polyclonal antibodies and therapeutic monoclonal…”
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Predictors for reactogenicity and humoral immunity to SARS-CoV-2 following infection and mRNA vaccination: A regularized, mixed-effects modelling approach by Williams, Erin C, Kizhner, Alexander, Stark, Valerie S, Nawab, Aria, Muniz, Daniel D, Echeverri Tribin, Felipe, Carreño, Juan Manuel, Bielak, Dominika, Singh, Gagandeep, Hoffer, Michael E, Krammer, Florian, Pallikkuth, Suresh, Pahwa, Savita

“…The influence of pre-existing humoral immunity, inter-individual demographic factors, and vaccine-associated reactogenicity on immunogenicity following COVID…”
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Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice by Strohmeier, Shirin, Carreño, Juan Manuel, Brito, Ruhi Nichalle, Krammer, Florian

“…Influenza virus surface glycoproteins represent the main targets of the immune system during infection and vaccination. Current influenza virus vaccines rely…”
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Evidence for retained spike-binding and neutralizing activity against emerging SARS-CoV-2 variants in serum of COVID-19 mRNA vaccine recipients by Carreño, Juan Manuel, Alshammary, Hala, Singh, Gagandeep, Raskin, Ariel, Amanat, Fatima, Amoako, Angela, Gonzalez-Reiche, Ana Silvia, van de Guchte, Adriana, study group, PARIS, Srivastava, Komal, Sordillo, Emilia Mia, Sather, D. Noah, van Bakel, Harm, Krammer, Florian, Simon, Viviana

“…Highly efficacious vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed. However, the emergence of viral variants…”
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