Search Results - "Manuel, Thomas"

Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety by Breining, Peter, Frølund, Anne Lier, Højen, Jesper Falkesgaard, Gunst, Jesper Damsgaard, Staerke, Nina B., Saedder, Eva, Cases‐Thomas, Manuel, Little, Paul, Nielsen, Lars Peter, Søgaard, Ole S., Kjolby, Mads

“…The coronavirus responsible for COVID‐19, SARS‐CoV‐2, utilizes a viral membrane spike protein for host cell entry. For the virus to engage in host membrane…”
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Divergent Synthesis of Cyclopropane‐Containing Lead‐Like Compounds, Fragments and Building Blocks through a Cobalt Catalyzed Cyclopropanation of Phenyl Vinyl Sulfide by Chawner, Stephen J., Cases‐Thomas, Manuel J., Bull, James A.

“…Cyclopropanes provide important design elements in medicinal chemistry and are widely present in drug compounds. Here we describe a strategy and extensive…”
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Anterior cingulate cortex causally supports flexible learning under motivationally challenging and cognitively demanding conditions by Banaie Boroujeni, Kianoush, Sigona, Michelle K, Treuting, Robert Louie, Manuel, Thomas J, Caskey, Charles F, Womelsdorf, Thilo

“…Anterior cingulate cortex (ACC) and striatum (STR) contain neurons encoding not only the expected values of actions, but also the value of stimulus features…”
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Sodium Hypochlorite Concentration and Postendodontic Pain - Unveiling the Optimal Balance: A Systematic Review and Meta-Analysis by Prasad, Niharika, Dasson Bajaj, Parul, Shenoy, Ramya, Dutta, Arindam, Thomas, Manuel S.

“…This study systematically reviewed literature regarding the effect of different concentrations of sodium hypochlorite (NaOCl) used during root canal treatment…”
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Ultrasound neuromodulation depends on pulse repetition frequency and can modulate inhibitory effects of TTX by Manuel, Thomas J., Kusunose, Jiro, Zhan, Xiaoyan, Lv, Xiaohui, Kang, Ellison, Yang, Aaron, Xiang, Zixiu, Caskey, Charles F.

“…Ultrasound is gaining traction as a neuromodulation method due to its ability to remotely and non-invasively modulate neuronal activity with millimeter…”
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Design of a 1-MHz therapeutic ultrasound array for small volume blood-brain barrier opening at cortical targets in macaques by Manuel, Thomas J., Anthony Phipps, M., Caskey, Charles F.

“…Focused ultrasound (FUS) can temporarily open the blood brain barrier (BBB) and increase the delivery of chemotherapeutics, viral vectors, and other agents to…”
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An Electrochemistry Study of Cryoelectrolysis in Frozen Physiological Saline by Manuel, Thomas J., Munnangi, Pujita, Rubinsky, Boris

“…Cryoelectrolysis is a new minimally invasive tissue ablation surgical technique that combines the processes of electrolysis and solid/liquid phase…”
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Technique Tips: A Reflection on Mouth Mirrors: Types, Usage and Modifications by Bishayi, Debolina, Suvarna, Kavya, Singh, Surmayee, Dutta, Arindam, Thomas, Manuel S

“…The mouth mirror is an essential tool in the dental armamentarium. Among its many functions, the most significant is being able to visualize aspects of the…”
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Reduced-field of view three-dimensional MR acoustic radiation force imaging with a low-rank reconstruction for targeting transcranial focused ultrasound by Luo, Huiwen, Sigona, Michelle K, Manuel, Thomas J, Phipps, Marshal A, Chen, Li M, Caskey, Charles F, Grissom, William A

“…To rapidly image and localize the focus in MR-guided focused ultrasound (FUS) while maintaining a low ultrasound duty cycle to minimize tissue effects…”
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Photocatalytic metallic nanomaterials immobilised onto porous structures: Future perspectives for at-source pharmaceutical removal from hospital wastewater and potential benefits over existing technologies by Valdivia, Manuel-Thomas, Taggart, Mark A., Pap, Sabolc, Kean, Alistair, Pfleger, Sharon, Megson, Ian L.

“…Active pharmaceutical ingredients (APIs) are continuously released via hospital effluents and have been shown to be toxic to aquatic organisms, even at very…”
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Catalyst-free Click PEGylation reveals substantial mitochondrial ATP synthase sub-unit alpha oxidation before and after fertilisation by Cobley, James N, Noble, Anna, Jimenez-Fernandez, Eduardo, Valdivia Moya, Manuel-Thomas, Guille, Matthew, Husi, Holger

“…Using non-reducing Western blotting to assess protein thiol redox state is challenging because most reduced and oxidised forms migrate at the same molecular…”
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Small volume blood-brain barrier opening in macaques with a 1 MHz ultrasound phased array by Manuel, Thomas J., Sigona, Michelle K., Phipps, M. Anthony, Kusunose, Jiro, Luo, Huiwen, Yang, Pai-Feng, Newton, Allen T., Gore, John C., Grissom, William, Chen, Li Min, Caskey, Charles F.

“…The use of focused ultrasound to open the blood-brain barrier (BBB) has the potential to deliver drugs to specific regions of the brain. The size of the BBB…”
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Practical Targeting Errors During Optically Tracked Transcranial Focused Ultrasound Using MR-ARFI and Array- Based Steering by Phipps, M. Anthony, Manuel, Thomas J., Sigona, Michelle K., Luo, Huiwen, Yang, Pai-Feng, Newton, Allen, Chen, Li Min, Grissom, William, Caskey, Charles F.

“…Objective: Transcranial focused ultrasound (tFUS) is being explored for neuroscience research and clinical applications due to its ability to affect precise…”
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Taylor Dispersion Analysis of Polysaccharides Using Backscattering Interferometry by Saetear, Phoonthawee, Chamieh, Joseph, Kammer, Michael N, Manuel, Thomas J, Biron, Jean-Philippe, Bornhop, Darryl J, Cottet, Hervé

“…Taylor dispersion analysis (TDA) allows the determination of the molecular diffusion coefficient (D) or the hydrodynamic radius (R h) of a solute from the peak…”
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Design and Validation of a Patient-Specific Stereotactic Frame for Transcranial Ultrasound Therapy by Kusunose, Jiro, Rodriguez, William J., Luo, Huiwen, Manuel, Thomas J., Phipps, M. Anthony, Yang, Pai-Feng, Grissom, William A., Konrad, Peter E., Chen, Li Min, Dawant, Benoit M., Caskey, Charles F.

“…Transcranial-focused ultrasound (tFUS) procedures such as neuromodulation and blood-brain barrier (BBB) opening require precise focus placement within the…”
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Irrigant dynamics of a back-to-back double side-vented needle in root canals with various tapers: a computational fluid dynamics study by Singh, Surmayee, Zuber, Mohammad, Verekar, Prathmesh Pravin, Shetty, Tejaswini, Srikant, N., Thomas, Manuel S.

“…Understanding the apical pressure and irrigant flow patterns in root canals is crucial for safe and effective irrigation. Therefore, this study aimed to assess…”
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Evaluation of indirect pulp capping using pozzolan-based cement (ENDOCEM-Zr®) and mineral trioxide aggregate - A randomized controlled trial by Sharma, Ankita, Thomas, Manuel, Shetty, Neeta, Srikant, N

“…Background: Pulp capping should always be considered as the primary treatment of choice for teeth without irreversible pulpitis in lesions approaching dental…”
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Differential dose responses of transcranial focused ultrasound at brain regions indicate causal interactions by Yang, Pai-Feng, Phipps, M. Anthony, Newton, Allen T., Jonathan, Sumeeth, Manuel, Thomas J., Gore, John C., Grissom, William A., Caskey, Charles F., Chen, Li Min

“…We have previously shown that focused ultrasound (FUS) pulses in low pressure range exerted bidirectional and brain state-dependent neuromodulation in the…”
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Disrupting nociceptive information processing flow through transcranial focused ultrasound neuromodulation of thalamic nuclei by Mishra, Arabinda, Yang, Pai-Feng, Manuel, Thomas J., Newton, Allen T., Phipps, M. Anthony, Luo, Huiwen, Sigona, Michelle K., Reed, Jamie L., Gore, John C., Grissom, William A., Caskey, Charles F., Chen, Li Min

“…MRI-guided transcranial focused ultrasound (MRgFUS) as a next-generation neuromodulation tool can precisely target and stimulate deep brain regions with high…”
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Effects of online marketplace-sourced over-the-counter tooth whitening products on the colour, microhardness, and surface topography of enamel: an in vitro study by Agarwal, Radhika, Vasani, Nikki, Mense, Urmila Sachin, Prasad, Niharika, Shetty, Aditya, Natarajan, Srikant, Dutta, Arindam, Thomas, Manuel S.

“…Objectives This study compared the whitening effect, microhardness, and enamel surface alterations of over-the-counter (OTC) tooth bleaching products with…”
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