Search Results - "Mantso, Theodora"
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Effects of hyperthermia as a mitigation strategy in DNA damage-based cancer therapies
Published in Seminars in cancer biology (01-06-2016)“…Abstract Utilization of thermal therapy (hyperthermia) is defined as the application of exogenous heat induction and represents a concept that is far from new…”
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2
Toxicity Profiling of Biosurfactants Produced by Novel Marine Bacterial Strains
Published in International journal of molecular sciences (27-02-2021)“…Surface active agents (SAAs), currently used in modern industry, are synthetic chemicals produced from non-renewable sources, with potential toxic impacts on…”
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3
Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma
Published in Investigational new drugs (01-06-2020)“…Summary The anticancer activity of a series of novel synthesized, hydroxypyridone-based metal chelators (analogues of L- mimosine) was evaluated in an in vitro…”
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4
Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma
Published in European journal of nutrition (01-03-2020)“…Objective(s) Isothiocyanates (ITCs) are biologically active plant secondary metabolites capable of mediating various biological effects including modulation of…”
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5
Thermal activation of Ti(1-x)Au(x) thin films with enhanced hardness and biocompatibility
Published in Bioactive materials (01-09-2022)“…The lifetime of orthopaedic implants can be extended by coating the softer Ti6Al4V alloy with harder biocompatible thin films. In this work, thin films of…”
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6
A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma
Published in Investigational new drugs (01-08-2021)“…Summary Melanoma is an aggressive and highly metastatic type of skin cancer where the design of new therapies is of utmost importance for the clinical…”
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7
Efficient E. coli expression strategies for production of soluble human crystallin ALDH3A1
Published in PloS one (22-02-2013)“…Aldehyde dehydrogenase 3A1 (ALDH3A1) is a recently characterized corneal crystallin with its exact functions still being unclear. Expressing recombinant human…”
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8
Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer
Published in Antioxidants (11-12-2018)“…Skin cancer is among the most common cancer types accompanied by rapidly increasing incidence rates, thus making the development of more efficient therapeutic…”
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9
Development of a Novel Experimental In Vitro Model of Isothiocyanate-induced Apoptosis in Human Malignant Melanoma Cells
Published in Anticancer research (01-12-2016)Get full text
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10
Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss
Published in Pharmacology & therapeutics (Oxford) (01-09-2016)“…Excessive accumulation of fat as the result of more energy intake and less energy expenditure is known as obesity. Lipids are essential components in the human…”
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11
Enhanced mechanical and biocompatibility performance of Ti(1-x)Ag(x) coatings through intermetallic phase modification
Published in Materials characterization (01-12-2022)“…Advanced materials combining superior mechanical and biocompatibility performance are of significant interest to extend the lifetime of biomedical devices. In…”
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12
Human Aldehyde Dehydrogenases: A Superfamily of Similar Yet Different Proteins Highly Related to Cancer
Published in Cancers (01-09-2023)“…The superfamily of human aldehyde dehydrogenases (hALDHs) consists of 19 isoenzymes which are critical for several physiological and biosynthetic processes and…”
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13
Isothiocyanate-induced Cell Cycle Arrest in a Novel In Vitro Exposure Protocol of Human Malignant Melanoma (A375) Cells
Published in Anticancer research (01-02-2019)“…Several studies have documented the effects of isothiocyanates (ITCs) on cancer prevention by inducing oxidative stress, activating apoptosis, affecting…”
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14
Gold nanoparticles, radiations and the immune system: Current insights into the physical mechanisms and the biological interactions of this new alliance towards cancer therapy
Published in Pharmacology & therapeutics (Oxford) (01-10-2017)“…Considering both cancer's serious impact on public health and the side effects of cancer treatments, strategies towards targeted cancer therapy have lately…”
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15
Effectiveness of Hyperthermia as Monotherapy and Adjuvant Therapy Approaches Against an In Vitro Model of Colorectal Carcinoma
Published in Anticancer research (01-05-2022)“…Despite improvement in current therapies, the 5-year overall survival rate of colorectal carcinoma is still low especially in its metastatic form. On the other…”
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16
Human aldehyde dehydrogenase 3A1 (ALDH3A1) exhibits chaperone-like function
Published in The international journal of biochemistry & cell biology (01-08-2017)“…Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals,…”
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Hyperthermia Suppresses Post - In Vitro Proliferation and Tumor Growth in Murine Malignant Melanoma and Colon Carcinoma
Published in Anticancer research (01-05-2019)“…Several studies have highlighted hyperthermia's ability to enhance the effectiveness of radiation and chemotherapy in various in vitro and in vivo cancer…”
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18
Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells
Published in The international journal of biochemistry & cell biology (01-08-2016)“…Aldehyde dehydrogenases participate in a variety of cellular homeostatic mechanisms like metabolism, proliferation, differentiation, apoptosis, whereas…”
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19
Novel insights into hyperthermia's therapeutic effectiveness in treating malignant melanoma
Published 01-01-2018“…Malignant melanoma is one of the most aggressive types of human cancers and one of the deadliest malignancies with steadily increasing incidence rates…”
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Dissertation -
20
DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer
Published in Mutation research (01-04-2019)“…DNA-dependent protein kinase (DNA-PK), a member of phosphatidylinositol-kinase family, is a key protein in mammalian DNA double-strand break (DSB) repair that…”
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