Search Results - "Mantis, J."

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut by Mantis, N J, Rol, N, Corthésy, B

“…Secretory IgA (SIgA) serves as the first line of defense in protecting the intestinal epithelium from enteric toxins and pathogenic microorganisms. Through a…”
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PM10-bound polycyclic aromatic hydrocarbons (PAHs) in the Greater Area of Athens, Greece by Mantis, J., Chaloulakou, A., Samara, C.

“…Polycyclic aromatic hydrocarbons (PAHs) associated to ambient PM10 were determined at four sites within the Greater Athens Area (GAA), Greece, during the…”
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A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking by Herrera, Cristina, Klokk, Tove Irene, Cole, Richard, Sandvig, Kirsten, Mantis, Nicholas J

“…JJX12 is an engineered bispecific antibody against ricin, a member of the medically important A-B family of toxins that exploits retrograde transport as means…”
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The prospect of orally administered monoclonal secretory IgA (SIgA) antibodies to prevent enteric bacterial infections by Richards, Angelene, Baranova, Danielle, Mantis, Nicholas J.

“…Eliminating diarrheal diseases as a leading cause of childhood morbidity and mortality in low- and middle-income countries (LMICs) will require multiple…”
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Flagellar-based motility accelerates IgA-mediated agglutination of Salmonella Typhimurium at high bacterial cell densities by Lindberg, Samantha K, Willsey, Graham G, Mantis, Nicholas J

“…Secretory IgA (SIgA) protects the intestinal epithelium from enteric pathogens such as Salmonella enterica serovar Typhimurium (STm) through a process known as…”
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Sites of vulnerability on ricin B chain revealed through epitope mapping of toxin-neutralizing monoclonal antibodies by Vance, David J, Poon, Amanda Y, Mantis, Nicholas J

“…Ricin toxin's B subunit (RTB) is a multifunctional galactose (Gal)-/N-acetylgalactosamine (GalNac)-specific lectin that promotes uptake and intracellular…”
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Editorial: Mucosal Vaccination: Strategies to Induce and Evaluate Mucosal Immunity by Kozlowski, Pamela A, Mantis, Nicholas J, Frey, Andreas

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Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut by Mantis, N J, Rol, N, Corthésy, B

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Vibrio cholerae O1 secretes an extracellular matrix in response to antibody-mediated agglutination by Baranova, Danielle E, Levinson, Kara J, Mantis, Nicholas J

“…Vibrio cholerae O1 is one of two serogroups responsible for epidemic cholera, a severe watery diarrhea that occurs after the bacterium colonizes the human…”
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Inhibition of invasive salmonella by orally administered IgA and IgG monoclonal antibodies by Richards, Angelene F, Doering, Jennifer E, Lozito, Shannon A, Varrone, John J, Willsey, Graham G, Pauly, Michael, Whaley, Kevin, Zeitlin, Larry, Mantis, Nicholas J

“…Non-typhoidal Salmonella enterica strains, including serovar Typhimurium (STm), are an emerging cause of invasive disease among children and the…”
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Secretory IgA: Arresting Microbial Pathogens at Epithelial Borders by Mantis, Nicholas J., Forbes, Stephen J.

“…Secretory IgA (SIgA) is the predominant class of antibody found in intestinal secretions. Although SIgA's role in protecting the intestinal epithelium from the…”
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Role of Maternal Dietary Peanut Exposure in Development of Food Allergy and Oral Tolerance by Järvinen, Kirsi M, Westfall, Jennifer, De Jesus, Magdia, Mantis, Nicholas J, Carroll, Jessica A, Metzger, Dennis W, Sampson, Hugh A, Berin, M Cecilia

“…The impact of maternal ingestion of peanut during pregnancy and lactation on an offspring's risk for peanut allergy is under debate. To investigate the…”
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Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection by Roy, Chad J., Brey, Robert N., Mantis, Nicholas J., Mapes, Kelly, Pop, Iliodora V., Pop, Laurentiu M., Ruback, Stephen, Killeen, Stephanie Z., Doyle-Meyers, Lara, Vinet-Oliphant, Heather S., Didier, Peter J., Vitetta, Ellen S.

“…Significance Ricin toxin (RT) is a CDC-designated select agent that can be dispersed as an aerosol. In mammals, aerosolized RT causes rapid and irreversible…”
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FRUIT, a scar-free system for targeted chromosomal mutagenesis, epitope tagging, and promoter replacement in Escherichia coli and Salmonella enterica by Stringer, Anne M, Singh, Navjot, Yermakova, Anastasiya, Petrone, Brianna L, Amarasinghe, Jayaleka J, Reyes-Diaz, Lucia, Mantis, Nicholas J, Wade, Joseph T

“…Recombineering is a widely-used approach to delete genes, introduce insertions and point mutations, and introduce epitope tags into bacterial chromosomes. Many…”
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Inhibition of Salmonella enterica Serovar Typhimurium Motility and Entry into Epithelial Cells by a Protective Antilipopolysaccharide Monoclonal Immunoglobulin A Antibody by Forbes, Stephen J, Eschmann, Marisa, Mantis, Nicholas J

“…Secretory immunoglobulin A (SIgA) antibodies directed against the O antigen of lipopolysaccharide (LPS) are the primary determinants of mucosal immunity to…”
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A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles by De Jesus, Magdia, Ostroff, Gary R, Levitz, Stuart M, Bartling, Toni R, Mantis, Nicholas J

“…Glucan particles (GPs) are 2-4 μm hollow, porous shells composed of 1,3-β-D-glucan that have been effectively used for oral targeted-delivery of a wide range…”
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Demographic and Clinical Factors Associated With SARS-CoV-2 Spike 1 Antibody Response Among Vaccinated US Adults: the C4R Study by Kim, John S., Sun, Yifei, Balte, Pallavi, Cushman, Mary, Boyle, Rebekah, Tracy, Russell P., Styer, Linda M., Bell, Taison D., Anderson, Michaela R., Allen, Norrina B., Schreiner, Pamela J., Bowler, Russell P., Schwartz, David A., Lee, Joyce S., Xanthakis, Vanessa, Doyle, Margaret F., Regan, Elizabeth A., Make, Barry J., Kanaya, Alka M., Wenzel, Sally E., Coresh, Josef, Isasi, Carmen R., Raffield, Laura M., Elkind, Mitchell S. V., Howard, Virginia J., Ortega, Victor E., Woodruff, Prescott, Cole, Shelley A., Henderson, Joel M., Mantis, Nicholas J., Parker, Monica M., Demmer, Ryan T., Oelsner, Elizabeth C.

“…This study investigates correlates of anti-S1 antibody response following COVID-19 vaccination in a U.S. population-based meta-cohort of adults participating…”
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A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication by Rong, Yinghui, Pauly, Michael, Guthals, Adrian, Pham, Henry, Ehrbar, Dylan, Zeitlin, Larry, Mantis, Nicholas J

“…PB10 IgG , a monoclonal antibody (MAb) directed against an immunodominant epitope on the enzymatic subunit (RTA) of ricin toxin (RT), has been shown to…”
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Recognition of secretory IgA by DC-SIGN: Implications for immune surveillance in the intestine by Baumann, Jan, Park, Chae Gyu, Mantis, Nicholas J

“…Abstract Secretory IgA (SIgA), the predominant class of antibody in intestinal secretions, serves as the first line of defense against enteric infections. SIgA…”
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An intranasally administered monoclonal antibody cocktail abrogates ricin toxin-induced pulmonary tissue damage and inflammation by Rong, Yinghui, Torres-Velez, Fernando J., Ehrbar, Dylan, Doering, Jennifer, Song, Renjie, Mantis, Nicholas J.

“…Ricin toxin, a plant-derived, mannosylated glycoprotein, elicits an incapacitating and potentially lethal inflammatory response in the airways following…”
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