Search Results - "Mantilla, Brian Suarez"

Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch in Trypanosoma cruzi epimastigotes by Barisón, María Julia, Rapado, Ludmila Nakamura, Merino, Emilio F., Furusho Pral, Elizabeth Mieko, Mantilla, Brian Suarez, Marchese, Letícia, Nowicki, Cristina, Silber, Ariel Mariano, Cassera, Maria Belen

“…Trypanosoma cruzi, the etiological agent of Chagas disease, is a protozoan parasite with a complex life cycle involving a triatomine insect and mammals…”
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Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools by Marchese, Letícia, Olavarria, Karel, Mantilla, Brian Suarez, Avila, Carla Cristi, Souza, Rodolpho Ornitiz Oliveira, Damasceno, Flávia Silva, Elias, Maria Carolina, Silber, Ariel Mariano

“…In Trypanosoma cruzi, the etiological agent of Chagas disease, the amino acid proline participates in processes related to T. cruzi survival and infection,…”
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Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi by Paes, Lisvane Silva, Suárez Mantilla, Brian, Zimbres, Flávia Menezes, Pral, Elisabeth Mieko Furusho, Diogo de Melo, Patrícia, Tahara, Erich B, Kowaltowski, Alicia J, Elias, Maria Carolina, Silber, Ariel Mariano

“…Over the past three decades, L-proline has become recognized as an important metabolite for trypanosomatids. It is involved in a number of key processes,…”
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Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae by Buchensky, Celeste, Almirón, Paula, Mantilla, Brian Suarez, Silber, Ariel M, Cricco, Julia A

“…Trypanosoma cruzi, the etiologic agent for Chagas' disease, has requirements for several cofactors, one of which is heme. Because this organism is unable to…”
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Uptake of GABA in Trypanosoma cruzi by Galvez Rojas, Robert L, Ahn, Il‐Young, Suárez Mantilla, Brian, Sant'Anna, Celso, Pral, Elizabeth Mieko Furusho, Silber, Ariel Mariano

“…Gamma aminobutyric acid (GABA) is widely known as a neurotransmitter and signal transduction molecule found in vertebrates, plants, and some protozoan…”
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The Involvement of Glutamate Metabolism in the Resistance to Thermal, Nutritional, and Oxidative Stress in Trypanosoma cruzi by Magdaleno, Anahí, Suárez Mantilla, Brian, Rocha, Sandra C., Pral, Elizabeth M. F., Silber, Ariel M.

“…The inhibition of some glutamate metabolic pathways could lead to diminished parasite survival. In this study, the effects of L-methionine sulfoximine (MS),…”
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Cystathionine γ‐lyase, an Enzyme Related to the Reverse Transsulfuration Pathway, is Functional in Leishmania spp by Giordana, Lucila, Mantilla, Brian Suárez, Santana, Marianela, Silber, Ariel M, Nowicki, Cristina

“…Leishmania parasites seem capable of producing cysteine by de novo biosynthesis, similarly to bacteria, some pathogenic protists, and plants. In Leishmania…”
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Biochemical characterization of serine acetyltransferase and cysteine desulfhydrase from Leishmania major by Marciano, Daniela, Santana, Marianela, Mantilla, Brian Suárez, Silber, Ariel Mariano, Marino-Buslje, Cristina, Nowicki, Cristina

“…The nucleotide sequence annotated as LmjF32.2640 encodes a cysteine desulfhydrase. The Leishmania major enzyme is closely related to bacterial cystathionine β…”
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The Trypanosoma cruzi proteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae: Identification of heme A biosynthesis pathway in T. cruzi by Buchensky, Celeste, Almirón, Paula, Mantilla, Brian Suarez, Silber, Ariel M., Cricco, Julia A.

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The Trypanosoma cruziproteins TcCox10 and TcCox15 catalyze the formation of heme A in the yeast Saccharomyces cerevisiae by BUCHENSKY, Celeste, ALMIRON, Paula, SUAREZ MANTILLA, Brian, SILBER, Ariel M, CRICCO, Julia A

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Proline Dehydrogenase Regulates Redox State and Respiratory Metabolism in Trypanosoma cruzi. e69419 by Paes, Lisvane Silva, Mantilla, Brian Suarez, Zimbres, Flavia Menezes, Pral, Elisabeth MiekoFurusho, Melo, Patricia Diogode, Tahara, Erich B, Kowaltowski, Alicia J, Elias, Maria Carolina, Silber, Ariel Mariano

“…Over the past three decades, L-proline has become recognized as an important metabolite for trypanosomatids. It is involved in a number of key processes,…”
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The uniqueness of the Trypanosoma cruzi mitochondrion: opportunities to identify new drug target for the treatment of Chagas disease by Lisvane Silva, Paes, Mantilla, Brian Suárez, Barisón, Maria Julia, Wrenger, Carsten, Silber, Ariel Mariano

“…Trypanosoma cruzi is the causative agent of Chagas' disease, which affects some 8 - 10 million people in the Americas. The only two drugs approved for the…”
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