Search Results - "Mantilla, B."

Autophagy markers LC3 and p62 in aging lumbar motor neurons by Jahanian, Sepideh, Pareja-Cajiao, Miguel, Gransee, Heather M., Sieck, Gary C., Mantilla, Carlos B.

“…Autophagy is a ubiquitous process through which damaged cytoplasmic structures are recycled and degraded within cells. Aging can affect autophagy regulation in…”
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Aging reduces succinate dehydrogenase activity in rat type IIx/IIb diaphragm muscle fibers by Fogarty, Matthew J, Marin Mathieu, Natalia, Mantilla, Carlos B, Sieck, Gary C

“…In aged rats, diaphragm muscle (DIAm) reduced specific force and fiber cross-sectional area, sarcopenia, is selective for vulnerable type IIx and/or IIb DIAm…”
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Phrenic motor neuron loss in aged rats by Fogarty, Matthew J, Omar, Tanya S, Zhan, Wen-Zhi, Mantilla, Carlos B, Sieck, Gary C

“…Sarcopenia is the age-related reduction of muscle mass and specific force. In previous studies, we found that sarcopenia of the diaphragm muscle (DIAm) is…”
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Impact of Frailty on Outcomes After Primary and Revision Total Hip Arthroplasty by Johnson, Rebecca L., Abdel, Matthew P., Frank, Ryan D., Chamberlain, Alanna M., Habermann, Elizabeth B., Mantilla, Carlos B.

“…Frailty and disability from arthritis are closely intertwined and little is known about the impact of frailty on total hip arthroplasty (THA) outcomes. We…”
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Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection by Gransee, Heather M, Zhan, Wen-Zhi, Sieck, Gary C, Mantilla, Carlos B

“…Progressive recovery of rhythmic phrenic activity occurs over time after a spinal cord hemisection involving unilateral transection of anterolateral funiculi…”
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Localized delivery of brain-derived neurotrophic factor-expressing mesenchymal stem cells enhances functional recovery following cervical spinal cord injury by Gransee, Heather M, Zhan, Wen-Zhi, Sieck, Gary C, Mantilla, Carlos B

“…Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are important in modulating neuroplasticity and promoting recovery after spinal cord injury…”
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Genome‐Wide Association Study for Nine Plant Architecture Traits in Sorghum by Zhao, Jing, Mantilla Perez, Maria B., Hu, Jieyun, Salas Fernandez, Maria G.

“…Core Ideas The 101 SNPs were associated with at least one of nine plant architecture traits KS3 gene was associated with variation in seed number GA2ox5 gene…”
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CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells by Gonzalez Porras, Maria A., Gransee, Heather M., Denton, Travis T., Shen, Dunxin, Webb, Kevin L., Brinker, C. Jeffrey, Noureddine, Achraf, Sieck, Gary C., Mantilla, Carlos B.

“…Impaired autophagy, a cellular digestion process that eliminates proteins and damaged organelles, has been implicated in neurodegenerative diseases, including…”
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Functional impact of diaphragm muscle sarcopenia in both male and female mice by Greising, Sarah M, Mantilla, Carlos B, Medina-Martínez, Juan S, Stowe, Jessica M, Sieck, Gary C

“…To perform a range of ventilatory and nonventilatory behaviors, the diaphragm muscle (DIAm) must be able to generate sufficient forces throughout the lifespan…”
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Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model by Fogarty, Matthew J, Khurram, Obaid U, Mantilla, Carlos B, Sieck, Gary C

“…The neuromuscular junction (NMJ) mediates neural control of skeletal muscle fibers. Neurotrophic signaling, specifically brain derived neurotrophic factor…”
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Dissection of canopy layer-specific genetic control of leaf angle in Sorghum bicolor by RNA sequencing by Natukunda, Martha I, Mantilla-Perez, Maria B, Graham, Michelle A, Liu, Peng, Salas-Fernandez, Maria G

“…Leaf angle is an important plant architecture trait, affecting plant density, light interception efficiency, photosynthetic rate, and yield. The "smart canopy"…”
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Aging-related changes in respiratory system mechanics and morphometry in mice by Elliott, Jonathan E, Mantilla, Carlos B, Pabelick, Christina M, Roden, Anja C, Sieck, Gary C

“…Previous work investigating respiratory system mechanics in mice has reported an aging-related increase in compliance and mean linear intercept (Lm). However,…”
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TrkB kinase activity maintains synaptic function and structural integrity at adult neuromuscular junctions by Mantilla, Carlos B, Stowe, Jessica M, Sieck, Dylan C, Ermilov, Leonid G, Greising, Sarah M, Zhang, Chao, Shokat, Kevan M, Sieck, Gary C

“…Activation of the tropomyosin-related kinase receptor B (TrkB) by brain-derived neurotrophic factor acutely regulates synaptic transmission at adult…”
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Enhanced Diaphragm Muscle Function upon Satellite Cell Transplantation in Dystrophic Mice by Azzag, Karim, Gransee, Heather M, Magli, Alessandro, Yamashita, Aline M S, Tungtur, Sudheer, Ahlquist, Aaron, Zhan, Wen-Zhi, Onyebu, Chiemelie, Greising, Sarah M, Mantilla, Carlos B, Perlingeiro, Rita C R

“…The diaphragm muscle is essential for breathing, and its dysfunctions can be fatal. Many disorders affect the diaphragm, including muscular dystrophies…”
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The novel TrkB receptor agonist 7,8-dihydroxyflavone enhances neuromuscular transmission by Mantilla, Carlos B., Ermilov, Leonid G.

“…Neurotrophin signaling at the neuromuscular junction modulates cholinergic transmission and enhances neuromuscular transmission via the tropomyosin‐related…”
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Association mapping of brassinosteroid candidate genes and plant architecture in a diverse panel of Sorghum bicolor by Mantilla Perez, Maria B, Zhao, Jing, Yin, Yanhai, Hu, Jieyun, Salas Fernandez, Maria G

“…KEY MESSAGE: This first association analysis between plant architecture and BR candidate genes in sorghum suggests that natural allelic variation has…”
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Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons by Gill, Luther C, Gransee, Heather M, Sieck, Gary C, Mantilla, Carlos B

“…Highlights • Recovery of rhythmic diaphragm activity after spinal hemisection may be altered by modulating BDNF/TrkB signaling in phrenic motoneurons at…”
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The active transport of histidine and its role in ATP production in Trypanosoma cruzi by Barisón, M. J., Damasceno, F. S., Mantilla, B. S., Silber, A. M.

“…Trypanosoma cruzi , the aetiological agent of Chagas’s disease, metabolizes glucose, and after its exhaustion, degrades amino acids as energy source. Here, we…”
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Cervical spinal cord hemisection impacts sigh and the respiratory reset in male rats by Fogarty, Matthew J, Zhan, Wen-Zhi, Mantilla, Carlos B, Sieck, Gary C

“…Cervical spinal cord injury impacts ventilatory and non-ventilatory functions of the diaphragm muscle (DIAm) and contributes to clinical morbidity and…”
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Non-stationarity and power spectral shifts in EMG activity reflect motor unit recruitment in rat diaphragm muscle by Seven, Yasin B, Mantilla, Carlos B, Zhan, Wen-Zhi, Sieck, Gary C

“…Highlights ► The rat diaphragm muscle (DIAm) comprises different types of motor units, which are recruited to accomplish a wide range of motor behaviors. ►…”
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