Search Results - "Mansur, Rodrigo B."
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The Effect of Loneliness on Distinct Health Outcomes: A Comprehensive Review and Meta-Analysis
Published in Psychiatry research (01-12-2020)“…•Loneliness has been associated with adverse health outcomes, but few studies have evaluated its comparative effects on distinct health outcomes.•A scoping…”
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Inflamed moods: A review of the interactions between inflammation and mood disorders
Published in Progress in neuro-psychopharmacology & biological psychiatry (04-08-2014)“…Mood disorders have been recognized by the World Health Organization (WHO) as the leading cause of disability worldwide. Notwithstanding the established…”
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Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis
Published in Brain, behavior, and immunity (01-03-2022)“…•Fatigue and cognitive impairment are amongst the most common and debilitating symptoms of post-COVID-19 syndrome.•Approximately 1 in 3 individuals experienced…”
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Brain insulin resistance: A treatment target for cognitive impairment and anhedonia in depression
Published in Experimental neurology (01-05-2019)“…Type 2 Diabetes Mellitus (T2DM) and Major Depressive Disorder (MDD) are leading causes of disability worldwide. Indeed, both are costly and burdensome diseases…”
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Government response moderates the mental health impact of COVID-19: A systematic review and meta-analysis of depression outcomes across countries
Published in Journal of affective disorders (01-07-2021)“…•We hypothesized that timely government implementation of stringent measures to reduce COVID-19 transmission would benefit mental health, as evidenced by…”
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Applications of machine learning algorithms to predict therapeutic outcomes in depression: A meta-analysis and systematic review
Published in Journal of affective disorders (01-12-2018)“…•We surveyed the use of machine learning to inform predictive models in mood disorders.•We include studies that use machine learning algorithms to identify…”
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Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments
Published in Neuroscience and biobehavioral reviews (01-11-2018)“…•Mood disorders could have metabolic manifestations as part of the psychiatric syndrome.•Diet interventions present a unique and potentially useful treatment…”
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Cognitive impairment in major depressive disorder
Published in CNS spectrums (01-02-2019)“…Cognitive dysfunction is a symptomatic domain identified across many mental disorders. Cognitive deficits in individuals with major depressive disorder (MDD)…”
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The Effects of Ketamine on Cognition in Treatment-Resistant Depression: A Systematic Review and Priority Avenues for Future Research
Published in Neuroscience and biobehavioral reviews (01-01-2021)“…•Intravenous administration of ketamine is not associated with anti-cognitive effects.•IV ketamine in patients with TRD may have pro-cognitive effects in brain…”
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Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: Evidence, pathophysiology and treatment implications
Published in Journal of affective disorders (01-12-2015)“…Abstract Background Bipolar disorder (BD) has been associated with cognitive impairment during depressed, manic and euthymic periods. Inflammation has been…”
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Anti-inflammatory agents in the treatment of bipolar depression: a systematic review and meta-analysis
Published in Bipolar disorders (01-03-2016)“…Objective Inflammation has been implicated in the risk, pathophysiology, and progression of mood disorders and, as such, has become a target of interest in the…”
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Comparative efficacy and acceptability of antidiabetic agents for Alzheimer's disease and mild cognitive impairment: A systematic review and network meta‐analysis
Published in Diabetes, obesity & metabolism (01-10-2018)“…This study (registered with PROSPERO, CRD42018085967) compares the efficacy (i.e. pro‐cognitive effects) and acceptability of antidiabetic agents for…”
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The role of oxidative and nitrosative stress in accelerated aging and major depressive disorder
Published in Progress in neuro-psychopharmacology & biological psychiatry (04-02-2016)“…Major depressive disorder (MDD) affects millions of individuals and is highly comorbid with many age-associated diseases such as diabetes mellitus,…”
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Molecular Mechanisms of Psilocybin and Implications for the Treatment of Depression
Published in CNS drugs (01-01-2022)“…Therapeutic deficiencies with monoaminergic antidepressants invites the need to identify and develop novel rapid-acting antidepressants. Hitherto, ketamine and…”
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The theory of bipolar disorder as an illness of accelerated aging: Implications for clinical care and research
Published in Neuroscience and biobehavioral reviews (01-05-2014)“…Bipolar Disorder (BD) has been conceptualized as both a cyclic and a progressive disorder. Mechanisms involved in neuroprogression in BD remain largely unknown…”
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Cognitive dysfunction and metabolic comorbidities in mood disorders: A repurposing opportunity for glucagon-like peptide 1 receptor agonists?
Published in Neuropharmacology (01-07-2018)“…Major depressive disorder and bipolar disorder are highly prevalent and disabling conditions. Cognition is considered a core domain of their psychopathology…”
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Registered clinical trials investigating treatment of long COVID: a scoping review and recommendations for research
Published in Infectious diseases (London, England) (03-07-2022)“…A considerable proportion of individuals report persistent, debilitating and disparate symptoms despite resolution of acute COVID-19 infection (i.e. long…”
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The effect of caloric restriction on working memory in healthy non-obese adults
Published in CNS spectrums (01-02-2020)“…We aim to evaluate the effect of caloric restriction (CR) in cognition by comparing performance in neuropsychological tests for working memory between a group…”
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The Efficacy of Vortioxetine on Anhedonia in Patients With Major Depressive Disorder
Published in Frontiers in psychiatry (2019)“…Anhedonia is a common, persistent, and disabling phenomenon in treated adults with Major Depressive Disorder (MDD). Hitherto, relatively few antidepressant…”
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Novel therapeutic targets in depression: Minocycline as a candidate treatment
Published in Behavioural brain research (01-12-2012)“…► Regional cell loss and brain atrophy in mood disorders may be a consequence of impaired neuroplasticity. ► Neuroplasticity is regulated by neurotrophic,…”
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