Search Results - "Mansuet Lupo, Audrey"

Body Mass Index and Total Psoas Area Affect Outcomes In Patients Undergoing Pneumonectomy for Cancer by Hervochon, Remi, MD, Bobbio, Antonio, MD, PhD, Guinet, Claude, MD, PhD, Mansuet-Lupo, Audrey, MD, PhD, Rabbat, Antoine, MD, Régnard, Jean-François, MD, Roche, Nicolas, MD, PhD, Damotte, Diane, MD, PhD, Iannelli, Antonio, MD, PhD, Alifano, Marco, MD, PhD

“…Background Hypothesizing that morphometric measurements are reliable markers of fitness in patients with lung cancer requiring aggressive surgical…”
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Pericardial effusion under nivolumab: case-reports and review of the literature by Saade, Anastasia, Mansuet-Lupo, Audrey, Arrondeau, Jennifer, Thibault, Constance, Mirabel, Mariana, Goldwasser, François, Oudard, Stéphane, Weiss, Laurence

“…BackgroundNivolumab, a programmed death-1 (PD-1) inhibitor, is an immune checkpoint inhibitor particularly used in the treatment of malignant melanoma,…”
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NF1 mutations identify molecular and clinical subtypes of lung adenocarcinomas by Tlemsani, Camille, Pécuchet, Nicolas, Gruber, Aurelia, Laurendeau, Ingrid, Danel, Claire, Riquet, Marc, Le Pimpec‐Barthes, Françoise, Fabre, Elizabeth, Mansuet‐Lupo, Audrey, Damotte, Diane, Alifano, Marco, Luscan, Armelle, Rousseau, Benoit, Vidaud, Dominique, Varin, Jennifer, Parfait, Beatrice, Bieche, Ivan, Leroy, Karen, Laurent‐Puig, Pierre, Terris, Benoit, Blons, Helene, Vidaud, Michel, Pasmant, Eric

“…The tumor suppressor gene neurofibromin 1 (NF1) is a major regulator of the RAS‐MAPK pathway. NF1 mutations occur in lung cancer but were not extensively…”
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TP53, STK11 , and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti-PD-1 in Lung Adenocarcinoma by Biton, Jérôme, Mansuet-Lupo, Audrey, Pécuchet, Nicolas, Alifano, Marco, Ouakrim, Hanane, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Goldwasser, François, Leroy, Karen, Goc, Jeremy, Wislez, Marie, Germain, Claire, Laurent-Puig, Pierre, Dieu-Nosjean, Marie-Caroline, Cremer, Isabelle, Herbst, Ronald, Blons, Hélène, Damotte, Diane

“…By unlocking antitumor immunity, antibodies targeting programmed cell death 1 (PD-1) exhibit impressive clinical results in non-small cell lung cancer,…”
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Updated Prognostic Factors in Localized NSCLC by Garinet, Simon, Wang, Pascal, Mansuet-Lupo, Audrey, Fournel, Ludovic, Wislez, Marie, Blons, Hélène

“…Lung cancer is the most common cause of cancer mortality worldwide, and non-small cell lung cancer (NSCLC) represents 80% of lung cancer subtypes. Patients…”
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Lung Cancer That Harbors an HER2 Mutation: Epidemiologic Characteristics and Therapeutic Perspectives by Mazières, Julien, Peters, Solange, Lepage, Benoit, Cortot, Alexis B., Barlesi, Fabrice, Beau-Faller, Michéle, Besse, Benjamin, Blons, Hélène, Mansuet-Lupo, Audrey, Urban, Thierry, Moro-Sibilot, Denis, Dansin, Eric, Chouaid, Christos, Wislez, Marie, Diebold, Joachim, Felip, Enriqueta, Rouquette, Isabelle, Milia, Julie D., Gautschi, Oliver

“…HER2 mutations are identified in approximately 2%of non-small-cell lung cancers (NSCLC). There are few data available that describe the clinical course of…”
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The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort by Damotte, Diane, Warren, Sarah, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Mansuet-Lupo, Audrey, Biton, Jérôme, Ouakrim, Hanane, Alifano, Marco, Gervais, Claire, Bellesoeur, Audrey, Kramkimel, Nora, Tlemsani, Camille, Burroni, Barbara, Duche, Angéline, Letourneur, Franck, Si, Han, Halpin, Rebecca, Creasy, Todd, Herbst, Ronald, Ren, Xing, Morel, Pascale, Cesano, Alessandra, Goldwasser, François, Leroy, Karen

“…The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its…”
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Pre-Disease and Pre-Surgery BMI, Weight Loss and Sarcopenia Impact Survival of Resected Lung Cancer Independently of Tumor Stage by Icard, Philippe, Schussler, Olivier, Loi, Mauro, Bobbio, Antonio, Lupo, Audrey Mansuet, Wislez, Marie, Iannelli, Antonio, Fournel, Ludovic, Damotte, Diane, Alifano, Marco

“…Lower pre-surgery Body Mass Index (BMI) and low muscle mass impact negatively long-term survival of non-small cell lung cancer (NSCLC). We investigated their…”
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Clinical and molecular characteristics associated with high PD-L1 expression in EGFR-mutated lung adenocarcinoma by Slomka, Jeremy, Berthou, Hugo, Mansuet-Lupo, Audrey, Blons, Hélène, Fabre, Elizabeth, Lerner, Ivan, Rance, Bastien, Alifano, Marco, Chapron, Jeanne, Birsen, Gary, Gibault, Laure, Arrondeau, Jennifer, Leroy, Karen, Wislez, Marie

“…Objective Recent evidence suggests that elevated levels of PD-L1 expression may be linked to early resistance to TKI and reduced survival in NSCLC with EGFR…”
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Systemic inflammation, nutritional status and tumor immune microenvironment determine outcome of resected non-small cell lung cancer by Alifano, Marco, Mansuet-Lupo, Audrey, Lococo, Filippo, Roche, Nicolas, Bobbio, Antonio, Canny, Emelyne, Schussler, Olivier, Dermine, Hervé, Régnard, Jean-François, Burroni, Barbara, Goc, Jérémy, Biton, Jérôme, Ouakrim, Hanane, Cremer, Isabelle, Dieu-Nosjean, Marie-Caroline, Damotte, Diane

“…Hypothesizing that nutritional status, systemic inflammation and tumoral immune microenvironment play a role as determinants of lung cancer evolution, the…”
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Mitochondrial metabolism sustains CD8+ T cell migration for an efficient infiltration into solid tumors by Simula, Luca, Fumagalli, Mattia, Vimeux, Lene, Rajnpreht, Irena, Icard, Philippe, Birsen, Gary, An, Dongjie, Pendino, Frédéric, Rouault, Adrien, Bercovici, Nadège, Damotte, Diane, Lupo-Mansuet, Audrey, Alifano, Marco, Alves-Guerra, Marie-Clotilde, Donnadieu, Emmanuel

“…The ability of CD8 + T cells to infiltrate solid tumors and reach cancer cells is associated with improved patient survival and responses to immunotherapy…”
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Predictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control Study by Tiako Meyo, Manuela, Jouinot, Anne, Giroux-Leprieur, Etienne, Fabre, Elizabeth, Wislez, Marie, Alifano, Marco, Leroy, Karen, Boudou-Rouquette, Pascaline, Tlemsani, Camille, Khoudour, Nihel, Arrondeau, Jennifer, Thomas-Schoemann, Audrey, Blons, Hélène, Mansuet-Lupo, Audrey, Damotte, Diane, Vidal, Michel, Goldwasser, François, Alexandre, Jérôme, Blanchet, Benoit

“…A large interindividual variability has been observed in anti Programmed cell Death 1 (anti-PD1) therapies efficacy. The aim of this study is to assess the…”
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Thoracic Endometriosis Syndrome Other Than Pneumothorax: Clinical and Pathological Findings by Bobbio, Antonio, Canny, Emeline, Mansuet Lupo, Audrey, Lococo, Filippo, Legras, Antoine, Magdeleinat, Pierre, Regnard, Jean-François, Gompel, Anne, Damotte, Diane, Alifano, Marco

“…Thoracic endometriosis syndrome refers to a broad spectrum of clinical manifestations related to the presence of ectopic intrathoracic endometrial tissue. Few…”
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Chemoresistant pleomorphic rhabdomyosarcoma: whole exome sequencing reveals underlying cancer predisposition and therapeutic options by Tlemsani, Camille, Leroy, Karen, Gimenez-Roqueplo, Anne-Paule, Mansuet-Lupo, Audrey, Pasmant, Eric, Larousserie, Frederique, Boudou-Rouquette, Pascaline, Vidaud, Michel, Cadranel, Jacques, Blons, Helene, Goldwasser, Francois, Laurent-Puig, Pierre

“…Rhabdomyosarcoma (RMS) is rare cancer affecting children and adults. Pleomorphic RMS histology is almost exclusive to adult patients and often resistant to…”
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Micronodular thymic carcinoma with lymphoid hyperplasia: relevance of immunohistochemistry with a small panel of antibodies for diagnosis—a RYTHMIC study by Thomas de Montpreville, Vincent, Mansuet-Lupo, Audrey, Le Naoures, Cécile, Chalabreysse, Lara, De Muret, Anne, Hofman, Véronique, Rouquette, Isabelle, Piton, Nicolas, Dubois, Romain, Benitez, Jose Carlos, Girard, Nicolas, Besse, Benjamin, Marx, Alexander, Molina, Thierry Jo

“…Micronodular thymic carcinoma with lymphoid hyperplasia (MNTCLH) is a rare form of thymic carcinoma. We present the experience of RYTHMIC, the French national…”
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Comparison of juvenile and adult myasthenia gravis in a French cohort with focus on thymic histology by Truffault, Frédérique, Auger, Ludivine, Dragin, Nadine, Vilquin, Jean-Thomas, Fadel, Elie, Thomas de Montpreville, Vincent, Mansuet-Lupo, Audrey, Regnard, Jean-François, Alifano, Marco, Sharshar, Tarek, Behin, Anthony, Eymard, Bruno, Bolgert, Francis, Demeret, Sophie, Berrih-Aknin, Sonia, Le Panse, Rozen

“…Myasthenia gravis (MG) is an autoimmune disease characterized by muscle fatigability due to acetylcholine receptor (AChR) autoantibodies. To better…”
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The New Histologic Classification of Lung Primary Adenocarcinoma Subtypes Is a Reliable Prognostic Marker and Identifies Tumors With Different Mutation Status by Mansuet-Lupo, Audrey, MD, Bobbio, Antonio, MD, PhD, Blons, Hélène, PharmD, PhD, Becht, Etienne, Ouakrim, Hanane, Didelot, Audrey, Charpentier, Marie-Christine, MD, Bain, Serge, Marmey, Béatrice, Bonjour, Patricia, Biton, Jérôme, PhD, Cremer, Isabelle, PhD, Dieu-Nosjean, Marie-Caroline, PhD, Sautès-Fridman, Catherine, PhD, Régnard, Jean-François, MD, Laurent-Puig, Pierre, MD, PhD, Alifano, Marco, MD, PhD, FCCP, Damotte, Diane, MD, PhD

“…BACKGROUND Histologic classification of lung adenocarcinoma subtype has a prognostic value in most studies. However, lung adenocarcinoma characteristics differ…”
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French multicentric validation of ALK rearrangement diagnostic in 547 lung adenocarcinomas by Lantuejoul, Sylvie, Rouquette, Isabelle, Blons, Hélène, Le Stang, Nolwenn, Ilie, Marius, Begueret, Hugues, Grégoire, Valerie, Hofman, Paul, Gros, Audrey, Garcia, Stephane, Monhoven, Nathalie, Devouassoux-Shisheboran, Mojgan, Mansuet-Lupo, Audrey, Thivolet, Françoise, Antoine, Martine, Vignaud, Jean-Michel, Penault-Llorca, Frederique, Galateau-Sallé, Françoise, McLeer-Florin, Anne

“…Anaplastic lymphoma kinase (ALK) gene rearrangements in lung adenocarcinoma result in kinase activity targetable by crizotinib. Although fluorescence in situ…”
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EBV-Positive Inflammatory Follicular Dendritic Cell Sarcoma of the Spleen: Report of an Aggressive Form With Molecular Characterization by Baber, Alistair, Legendre, Paul, Palmic, Patricia, Lupo-Mansuet, Audrey, Burroni, Barbara, Azoulay, Célia, Szwebel, Tali-Anne, Costedoat-Chalumeau, Nathalie, Leroy, Karen, Blons, Hélène, Blay, Jean-Yves, Boudou-Rouquette, Pascaline, Terrier, Benjamin

“…EBV-positive inflammatory follicular dendritic cell sarcoma (EBV+ inflammatory FDCS) is a rare neoplasm almost exclusively located in the spleen or liver. It…”
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Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotinib by Younes, Mohamad, Wu, Zherui, Dupouy, Sandra, Lupo, Audrey Mansuet, Mourra, Najat, Takahashi, Takashi, Fléjou, Jean François, Trédaniel, Jean, Régnard, Jean François, Damotte, Diane, Alifano, Marco, Forgez, Patricia

“…Alterations in the signaling pathways of epidermal growth factor receptors (HERs) are associated with tumor aggressiveness. Neurotensin (NTS) and its high…”
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