Search Results - "Mansour, Hend"
-
1
The AMPK modulator metformin as adjunct to methotrexate in patients with rheumatoid arthritis: A proof-of-concept, randomized, double-blind, placebo-controlled trial
Published in International immunopharmacology (01-06-2021)“…•The co-administration of metformin to rheumatoid patients has reduced the disease activity.•Metformin treatment decreases the expression of inflammatory…”
Get full text
Journal Article -
2
Ginger Extract Loaded into Chitosan Nanoparticles Enhances Cytotoxicity and Reduces Cardiotoxicity of Doxorubicin in Hepatocellular Carcinoma in Mice
Published in Nutrition and cancer (31-12-2021)“…This study aimed to investigate the impact of ginger extract (GE) loaded into chitosan nanoparticles (CNPs) in enhancing cytotoxicity and reducing…”
Get full text
Journal Article -
3
Enhanced neuroprotective effect of verapamil-loaded hyaluronic acid modified carbon quantum dots in an in-vitro model of amyloid-induced Alzheimer's disease
Published in International journal of biological macromolecules (01-08-2024)“…This study aims to investigate the molecular mechanisms and the neuroprotective effect of hyaluronic acid modified verapamil-loaded carbon quantum dots…”
Get full text
Journal Article -
4
Dioon rzedowskii: An antioxidant, antibacterial and anticancer plant extract with multi-faceted effects on cell growth and molecular signaling
Published in International immunopharmacology (10-05-2024)“…•The anticancer, antibacterial properties of the Dioon rzedowskii on liver and breast cancer cell lines and on solid Ehrlich carcinoma (SEC) mouse model was…”
Get full text
Journal Article -
5
Ginger extract adjuvant to doxorubicin in mammary carcinoma: study of some molecular mechanisms
Published in European journal of nutrition (01-04-2018)“…Purpose The present study aimed to investigate the molecular mechanisms underlying the anticancer properties of ginger extract (GE) in mice bearing solid…”
Get full text
Journal Article -
6
Valorization of by-products Derived from Onions and Potato: Extraction Optimization, Metabolic Profile, Outstanding Bioactivities, and Industrial Applications
Published in Waste and biomass valorization (01-06-2023)“…Huge quantities of vegetables and fruits by-products are discarded annually worldwide following the industrial food processing techniques. These biowastes were…”
Get full text
Journal Article -
7
Infertility diagnosis and management
Published in Beni-Suef University journal of basic and applied sciences (01-12-2023)“…Background One of the most stressful problems for married couples is infertility, which is a widespread health issue. It has been defined as a profound…”
Get full text
Journal Article -
8
Investigation of the phytochemical composition, antioxidant, antibacterial, anti-osteoarthritis, and wound healing activities of selected vegetable waste
Published in Scientific reports (10-08-2023)“…Agri-food wastes, produced following industrial food processing, are mostly discarded, leading to environmental hazards and losing the nutritional and…”
Get full text
Journal Article -
9
Mechanistic Insights of Neuroprotective Efficacy of Verapamil-Loaded Carbon Quantum Dots against LPS-Induced Neurotoxicity in Rats
Published in International journal of molecular sciences (16-07-2024)“…Alzheimer's disease (AD) is a neurodegenerative disease that badly impacts patients and their caregivers. AD is characterized by deposition of amyloid beta…”
Get full text
Journal Article -
10
Chronotherapeutic neuroprotective effect of verapamil against lipopolysaccharide-induced neuroinflammation in mice through modulation of calcium-dependent genes
Published in Molecular medicine (Cambridge, Mass.) (26-11-2022)“…BackgroundNeuroinflammation is a major mechanism in neurodegenerative diseases such as Alzheimer’s disease (AD), which is a major healthcare problem…”
Get full text
Journal Article -
11
Anticancer Effect of Cycas media: Molecular Basis Through Modulation of PI3K/AKT/mTOR Signaling Pathway
Published in Molecules (Basel, Switzerland) (01-11-2024)“…Many researchers are focusing on screening the biological activities of plants owing to their safety and possible pharmacological actions. Consequently, we…”
Get full text
Journal Article -
12
The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer’s Disease-like Condition: Mechanistic Insights
Published in Molecules (Basel, Switzerland) (01-09-2023)“…Background: Alzheimer’s disease (AD) is a common neurodegenerative disorder without effective treatment. Thymoquinone (TQ) has demonstrated potential in…”
Get full text
Journal Article -
13
Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway
Published in Tumor biology (01-05-2017)“…Since the incidence of breast cancer increases dramatically all over the world, the search for effective treatment is an urgent need. Metformin has…”
Get full text
Journal Article -
14
Care Bundle Approach for Oral Health Maintenance and Reduction of Ventilator-Associated Pneumonia
Published in Critical care nursing quarterly (01-10-2024)“…Caring for patients in the intensive care unit (ICU) creates competing priorities of interventions for nurses and other health care providers. Oral care might…”
Get full text
Journal Article -
15
Double‐blind, randomized, placebo‐controlled pilot study of the phosphodiesterase‐3 inhibitor cilostazol as an adjunctive to antidepressants in patients with major depressive disorder
Published in CNS neuroscience & therapeutics (01-12-2021)“…Aims Cilostazol (CLS) has shown antidepressant effect in cardiovascular patients, post‐stroke depression, and animal models through its neurotrophic and…”
Get full text
Journal Article -
16
Marrubium alysson L. Ameliorated Methotrexate-Induced Testicular Damage in Mice through Regulation of Apoptosis and miRNA-29a Expression: LC-MS/MS Metabolic Profiling
Published in Plants (Basel) (03-09-2022)“…Despite the efficient anti-cancer capabilities of methotrexate (MTX), it may induce myelosuppression, liver dysfunction and testicular toxicity. The purpose of…”
Get full text
Journal Article -
17
Therapeutic effect of Momordica charantia on cardiomyopathy in a diabetic maternal rat model
Published in Journal of experimental zoology. Part A, Ecological and integrative physiology (01-11-2024)“…Myocardial structural and functional abnormalities are hallmarks of diabetic cardiomyopathy (DCM), a chronic consequence of diabetes mellitus (DM). Maternal DM…”
Get full text
Journal Article -
18
RETRACTED: Double‐blind, randomized, placebo‐controlled pilot study of the phosphodiesterase‐3 inhibitor cilostazol as an adjunctive to antidepressants in patients with major depressive disorder
Published in CNS neuroscience & therapeutics (01-12-2021)“…AimsCilostazol (CLS) has shown antidepressant effect in cardiovascular patients, post-stroke depression, and animal models through its neurotrophic and…”
Get full text
Journal Article -
19
Cryoanalgesia for Reducing Unconscious Patients' Pain During Arterial Puncture
Published in Critical care nursing quarterly (01-10-2024)“…Arterial puncture is a painful procedure performed to assess patients' respiratory status. Pain is a stressful situation for unconscious patients as they…”
Get full text
Journal Article -
20
Evaluation Of Long-Term Complications Of Diabetes Mellitus In Dogs
Published in Benha Veterinary Medical Journal (Online) (01-10-2023)Get full text
Journal Article