Search Results - "Mansour, Heba M"

Melatonin counteracts polyethylene microplastics induced adreno-cortical damage in male albino rats by Farag, Amina A., Bayoumi, Heba, Radwaan, Shaimaa E., El Gazzar, Walaa Bayoumie, Youssef, Heba S., Nasr, Hend Elsayed, Badr, Amira M., Mansour, Heba M., Elalfy, Amira, Sayed, Alaa El-Din Hamid, Kharboush, Tayseir G., Aboelkomsan, Elshaimaa Ahmed Fahmy, Sliem, Rania E.

“…There are various substances that can disrupt the homeostatic mechanisms of the body, defined as endocrine-disrupting chemicals (EDCs). The persistent nature…”
Get full text

Melatonin Alleviates Intestinal Barrier Damaging Effects Induced by Polyethylene Microplastics in Albino Rats by El Gazzar, Walaa Bayoumie, Sliem, Rania E, Bayoumi, Heba, Nasr, Hend Elsayed, Shabanah, Manar, Elalfy, Amira, Radwaan, Shaimaa E, Gebba, Mohammed A, Mansour, Heba M, Badr, Amul M, Amer, Marwa Fathy, Ashour, Sara S, Morsi, Heba, Aboelkomsan, El Shaimaa Ahmed Fahmy, Baioumy, Bodour, Sayed, Alaa El-Din Hamid, Farag, Amina A

“…There have been concerns about the potential health risks posed by microplastics (MP). The detection of MP in a variety of food products revealed that humans…”
Get full text

Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer's disease by Mansour, Heba, Fawzy, Hala, El-Khatib, Aiman, Khattab, Mahmoud

“…Numerous molecular mechanisms are being examined in an attempt to discover disease-modifying drugs to slow down the underlying neurodegeneration in Alzheimer's…”
Get full text

The Preferential Therapeutic Potential of Chlorella vulgaris against Aflatoxin-Induced Hepatic Injury in Quail by Elbasuni, Sawsan S, Ibrahim, Samar S, Elsabagh, Rasha, Nada, Mai O, Elshemy, Mona A, Ismail, Ayman K, Mansour, Heba M, Ghamry, Heba I, Ibrahim, Samah F, Alsaati, Ilhaam, Abdeen, Ahmed, Said, Alshaimaa M

“…Aflatoxins (AFs) are the most detrimental mycotoxin, potentially hazardous to animals and humans. AFs in food threaten the health of consumers and cause liver…”
Get full text

The interference between SARS-COV-2 and Alzheimer’s disease: Potential immunological and neurobiological crosstalk from a kinase perspective reveals a delayed pandemic by Mansour, Heba M.

“…Coronavirus disease 2019 (COVID-19) has infected over 700 million people, with up to 30% developing neurological manifestations, including dementias. However,…”
Get full text

Potential Repositioning of Anti-cancer EGFR Inhibitors in Alzheimer’s Disease: Current Perspectives and Challenging Prospects by Mansour, Heba M., Fawzy, Hala M., El-Khatib, Aiman S., Khattab, Mahmoud M.

“…[Display omitted] •New therapeutic approaches have to be considered in Alzheimer’s disease (AD).•Pathways regulating cell duplication are significant…”
Get full text

Exploring Parkinson-associated kinases for CRISPR/Cas9-based gene editing: beyond alpha-synuclein by Mansour, Heba M, El-Khatib, Aiman S

“…Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substania nigra (SN) and is…”
Get full text

Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease by Mansour, Heba M., F Mohamed, Ahmed, Khattab, Mahmoud M., El-Khatib, Aiman S.

“…Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor deficits induced by dopaminergic neuronal death in the substantia nigra (SN)…”
Get full text

Lapatinib ditosylate rescues memory impairment in D-galactose/ovariectomized rats: Potential repositioning of an anti-cancer drug for the treatment of Alzheimer's disease by Mansour, Heba M., Fawzy, Hala M., El-Khatib, Aiman S., Khattab, Mahmoud M.

“…Epidermal growth factor receptor (EGFR) signaling plays a substantial role in learning and memory. The upregulation of EGFR has been embroiled in the…”
Get full text

Naringin protects mice from D-galactose-induced lung aging and mitochondrial dysfunction: Implication of SIRT1 pathways by Salama, Abeer A.A., Yassen, Noha N., Mansour, Heba M.

“…Aging is the leading risk factor for diminishing lung function, as well as injury and lung disorder. The target of our research was to examine the potential…”
Get full text

Pazopanib ameliorates rotenone-induced Parkinsonism in rats by suppressing multiple regulated cell death mechanisms by Mansour, Heba M., Mohamed, Ahmed F., Khattab, Mahmoud M., El-Khatib, Aiman S.

“…Parkinson’s disease (PD) is characterized by motor impairments and progressive dopaminergic neuronal death in the substantia nigra (SN). Recently, the…”
Get full text

Corrigendum to “Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease” [Eur. J. Pharmacol. 954 (2023) 175875] by Mansour, Heba M., Mohamed, Ahmed F., Khattab, Mahmoud M., El-Khatib, Aiman S.

Get full text

Inhibition of mitochondrial pyruvate carrier 1 by lapatinib ditosylate mitigates Alzheimer's-like disease in D-galactose/ovariectomized rats by Mansour, Heba M., Fawzy, Hala M., El-Khatib, Aiman S., Khattab, Mahmoud M.

“…Mitochondrial, autophagic impairment, excitotoxicity, and also neuroinflammation are implicated in Alzheimer's disease (AD) pathophysiology. We postulated that…”
Get full text

Kinases control of regulated cell death revealing druggable targets for Parkinson’s disease by Mansour, Heba M., Mohamed, Ahmed F., El-Khatib, Aiman S., Khattab, Mahmoud.M.

“…Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder in the world. Motor impairment seen in PD is associated with dopaminergic…”
Get full text

Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated parkinsonism in rats: Modulation of dopamine D3 receptor by Mansour, Heba M., Mohamed, Ahmed F., Khattab, Mahmoud. M., El-Khatib, Aiman S.

“…[Display omitted] •EGFR inhibitor lapatinib exerts neuroprotective effects in PD.•Modulation of dopamine D3 receptors may have therapeutic potential in…”
Get full text

Heat Shock Protein 90 in Parkinson's Disease: Profile of a Serial Killer by Mansour, Heba M, Mohamed, Ahmed F, Khattab, Mahmoud M, El-Khatib, Aiman S

“…Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized by abnormal α-synuclein misfolding and aggregation, mitochondrial…”
Get full text

Influence of nutrient supplementation and stress conditions on the biomass and lipid production of Microchloropsis salina for biodiesel production by El-Sheekh, Mostafa M., Mansour, Heba M., Bedaiwy, Mohamed Y., El-shenody, Rania A.

“…This work aimed to introduce a new technique for improving sustainable biodiesel from Microchloropsis salina by examining the impact of various nitrogen…”
Get full text

The anti-inflammatory and anti-fibrotic effects of tadalafil in thioacetamide-induced liver fibrosis in rats by Mansour, Heba M, Salama, Abeer A A, Abdel-Salam, Rania M, Ahmed, Naglaa A, Yassen, Noha N, Zaki, Hala F

“…Liver fibrosis is a health concern that leads to organ failure mediated via production of inflammatory cytokines and fibrotic biomarkers. This study aimed to…”
Get more information

The Preferential Therapeutic Potential of IChlorella vulgaris/I against Aflatoxin-Induced Hepatic Injury in Quail by Elbasuni, Sawsan S, Ibrahim, Samar S, Elsabagh, Rasha, Nada, Mai O, Elshemy, Mona A, Ismail, Ayman K, Mansour, Heba M, Ghamry, Heba I, Ibrahim, Samah F, Alsaati, Ilhaam, Abdeen, Ahmed, Said, Alshaimaa M

“…Aflatoxins (AFs) are the most detrimental mycotoxin, potentially hazardous to animals and humans. AFs in food threaten the health of consumers and cause liver…”
Get full text

Influence of salinity and various nitrogen sources on cell growth and lipid production of the green microalga Micractinium pusillum Fresen by El-Sheekh et al, Mostafa M.

Get full text