Search Results - "Mansor, Latt S"

Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation by Mansor, Latt S, Sousa Fialho, Maria da Luz, Yea, Georgina, Coumans, Will A, West, James A, Kerr, Matthew, Carr, Carolyn A, Luiken, Joost J F P, Glatz, Jan F C, Evans, Rhys D, Griffin, Julian L, Tyler, Damian J, Clarke, Kieran, Heather, Lisa C

“…The type 2 diabetic heart oxidizes more fat and less glucose, which can impair metabolic flexibility and function. Increased sarcolemmal fatty acid translocase…”
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Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation by Mansor, Latt S., Mehta, Keshavi, Aksentijevic, Dunja, Carr, Carolyn A., Lund, Trine, Cole, Mark A., Page, Lydia Le, Sousa Fialho, Maria da Luz, Shattock, Michael J., Aasum, Ellen, Clarke, Kieran, Tyler, Damian J, Heather, Lisa C.

“…Key points Adaptation to hypoxia makes the heart more oxygen efficient, by metabolising more glucose. In contrast, type 2 diabetes makes the heart metabolise…”
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Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin by Mansor, Latt S, Gonzalez, Eileen R, Cole, Mark A, Tyler, Damian J, Beeson, Jessica H, Clarke, Kieran, Carr, Carolyn A, Heather, Lisa C

“…To study the pathogenesis of diabetic cardiomyopathy, reliable animal models of type 2 diabetes are required. Physiologically relevant rodent models are…”
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