Search Results - "Mansoor, Samman"

Utilization of Biased G Protein-Coupled Receptor Signaling towards Development of Safer and Personalized Therapeutics by Ilter, Metehan, Mansoor, Samman, Sensoy, Ozge

“…G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have…”
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Gluten Exorphins Promote Cell Proliferation through the Activation of Mitogenic and Pro-Survival Pathways by Manai, Federico, Zanoletti, Lisa, Morra, Giulia, Mansoor, Samman, Carriero, Francesca, Bozzola, Elena, Muscianisi, Stella, Comincini, Sergio

“…Celiac disease (CD) is a chronic and systemic autoimmune disorder that affects preferentially the small intestine of individuals with a genetic predisposition…”
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Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer by Mansoor, Samman, Kayık, Gülru, Durdagi, Serdar, Sensoy, Ozge

“…[Display omitted] •Bivalent ligand;•modulates conformational preferences of and correlations among microswitches,•strengthens interaction between G protein and…”
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Linker residues regulate the activity and stability of hexokinase 2, a promising anticancer target by Ferreira, Juliana C., Khrbtli, Abdul-Rahman, Shetler, Cameron L., Mansoor, Samman, Ali, Liaqat, Sensoy, Ozge, Rabeh, Wael M.

“…Hexokinase (HK) catalyzes the first step in glucose metabolism, making it an exciting target for the inhibition of tumor initiation and progression due to…”
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Utilization of Biased G Protein-Coupled ReceptorSignaling towards Development of Safer andPersonalized Therapeutics by Ilter, Metehan, Mansoor, Samman, Sensoy, Ozge

“…G protein-coupled receptors (GPCRs) are involved in a wide variety of physiologicalprocesses. Therefore, approximately 40% of currently prescribed drugs have…”
Get full text