Ulcerative facial and nasal dermatitis and stomatitis in cats associated with feline herpesvirus 1

Ulcerative facial and nasal dermatitis and stomatitis in cats associated with feline herpesvirus 1

Ulcerative dermatitis of the nasal planum or haired skin of the face, associated with intranuclear inclusion bodies compatible with herpesvirus, was identified in nine cats. Clinically, lesions were ulcerative and crusted, and often persistent. A tenth cat had focal proliferative ulcerative stomatit...

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Bibliographic Details
Published in:Veterinary dermatology Vol. 10; no. 4; pp. 267 - 274
Main Authors: Hargis, A.M, Ginn, P.E, Mansell, J.E.K.L, Garber, R.L
Format: Journal Article
Language:English
Published: Oxford, UK Blackwell Science Ltd 01-12-1999
Subjects:
cats
dermatitis
face
Felid herpesvirus 1
feline
herpesvirus
histopathology
nuclear inclusions
PCR
polymerase chain reaction
skin
stomatitis
ulcer
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Summary:Ulcerative dermatitis of the nasal planum or haired skin of the face, associated with intranuclear inclusion bodies compatible with herpesvirus, was identified in nine cats. Clinically, lesions were ulcerative and crusted, and often persistent. A tenth cat had focal proliferative ulcerative stomatitis, also associated with intranuclear inclusion bodies. Microscopically, there was necrosis and ulceration associated with prominent eosinophilic inflammation. Intranuclear inclusion bodies were noted in all cases, within the surface or adnexal epithelium. Ultrastructural examination of skin from two cats revealed virions morphologically compatible with a herpesvirus. Polymerase chain reaction (PCR) specific for feline herpesvirus 1 on DNA extracted from fresh‐frozen or formalin‐fixed paraffin‐embedded biopsy samples and/or consensus primer PCR with DNA sequencing performed on DNA extracted from formalin‐fixed paraffin‐embedded biopsy samples from seven cats revealed that the virus was indistinguishable from feline herpesvirus 1. PCR was negative in one of eight cats tested.
Bibliography:istex:E1E63F1E49EAFFDE65F659DA969C4DFE9F78595F
ark:/67375/WNG-FLS20D7K-6
ArticleID:VDE145
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0959-4493
1365-3164
DOI:10.1046/j.1365-3164.1999.00145.x