Search Results - "Manseau, Frédéric"
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Optogenetic gamma stimulation rescues memory impairments in an Alzheimer’s disease mouse model
Published in Nature communications (22-11-2019)“…Slow gamma oscillations (30–60 Hz) correlate with retrieval of spatial memory. Altered slow gamma oscillations have been observed in Alzheimer’s disease. Here,…”
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2
Activation of specific neuronal networks leads to different seizure onset types
Published in Annals of neurology (01-03-2016)“…Objective Ictal events occurring in temporal lobe epilepsy patients and in experimental models mimicking this neurological disorder can be classified, based on…”
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Optogenetic Activation of Septal Glutamatergic Neurons Drive Hippocampal Theta Rhythms
Published in The Journal of neuroscience (09-03-2016)“…The medial septum and diagonal band of Broca (MS-DBB) has an essential role for theta rhythm generation in the hippocampus and is critical for learning and…”
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4
Interneuron activity leads to initiation of low-voltage fast-onset seizures
Published in Annals of neurology (01-03-2015)“…Seizures in temporal lobe epilepsy can be classified as hypersynchronous and low‐voltage fast according to their onset patterns. Experimental evidence suggests…”
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Parvalbumin Interneurons of Hippocampus Tune Population Activity at Theta Frequency
Published in Neuron (Cambridge, Mass.) (03-06-2015)“…Hippocampal theta rhythm arises from a combination of recently described intrinsic theta oscillators and inputs from multiple brain areas. Interneurons…”
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Specific imbalance of excitatory/inhibitory signaling establishes seizure onset pattern in temporal lobe epilepsy
Published in Journal of neurophysiology (01-06-2016)“…Low-voltage fast (LVF) and hypersynchronous (HYP) patterns are the seizure-onset patterns most frequently observed in intracranial EEG recordings from mesial…”
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Conjunctive spatial and self-motion codes are topographically organized in the GABAergic cells of the lateral septum
Published in PLoS biology (30-08-2021)“…The hippocampal spatial code’s relevance for downstream neuronal populations—particularly its major subcortical output the lateral septum (LS)—is still poorly…”
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Optogenetic Low-Frequency Stimulation of Specific Neuronal Populations Abates Ictogenesis
Published in The Journal of neuroscience (15-03-2017)“…Despite many advances made in understanding the pathophysiology of epileptic disorders, seizures remain poorly controlled in approximately one-third of…”
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9
Reversal of theta rhythm flow through intact hippocampal circuits
Published in Nature neuroscience (01-10-2014)“…Theta oscillations are thought to propagate unidirectionally along the hippocampal circuitry, from CA3 to CA1 and the subiculum. In this paper, Jackson and…”
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Excitatory Inputs Determine Phase-Locking Strength and Spike-Timing of CA1 Stratum Oriens/Alveus Parvalbumin and Somatostatin Interneurons during Intrinsically Generated Hippocampal Theta Rhythm
Published in The Journal of neuroscience (22-06-2016)“…Theta oscillations are essential for learning and memory, and their generation requires GABAergic interneurons. To better understand how theta is generated, we…”
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The Hippocamposeptal Pathway Generates Rhythmic Firing of GABAergic Neurons in the Medial Septum and Diagonal Bands: An Investigation Using a Complete Septohippocampal Preparation In Vitro
Published in The Journal of neuroscience (09-04-2008)“…The medial septum diagonal band area (MS/DB) projects to the hippocampus through the fornix/fimbria pathway and is implicated in generating hippocampal theta…”
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12
Factors affecting river turbidity in a degrading permafrost environment: the Tasiapik River, Umiujaq (Nunavik)
Published in Arctic science (01-12-2022)“…This study focuses on spatiotemporal changes in water turbidity in relation to permafrost to document the impact of meteorological conditions and water flow on…”
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Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit
Published in Journal of visualized experiments (02-08-2017)“…This protocol outlines the procedures for preparing and recording from the isolated whole hippocampus, of WT and transgenic mice, along with recent…”
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A Characterization of the Electrophysiological and Morphological Properties of Vasoactive Intestinal Peptide (VIP) Interneurons in the Medial Entorhinal Cortex (MEC)
Published in Frontiers in neural circuits (23-07-2021)“…Circuit interactions within the medial entorhinal cortex (MEC) translate movement into a coherent code for spatial location. Entorhinal principal cells are…”
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Electrophysiological and Morphological Characterization of Chrna2 Cells in the Subiculum and CA1 of the Hippocampus: An Optogenetic Investigation
Published in Frontiers in cellular neuroscience (13-02-2018)“…The nicotinic acetylcholine receptor alpha2 subunit (Chrna2) is a specific marker for oriens lacunosum-moleculare (OLM) interneurons in the dorsal CA1 region…”
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Desynchronization of neocortical networks by asynchronous release of GABA at autaptic and synaptic contacts from fast-spiking interneurons
Published in PLoS biology (01-09-2010)“…Networks of specific inhibitory interneurons regulate principal cell firing in several forms of neocortical activity. Fast-spiking (FS) interneurons are…”
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Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells
Published in Frontiers in cellular neuroscience (16-05-2017)“…Hippocampal interneurons release the inhibitory transmitter GABA to regulate excitation, rhythm generation and synaptic plasticity. A subpopulation of…”
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NMDA-dependent phase synchronization between septal and temporal CA3 hippocampal networks
Published in The Journal of neuroscience (08-05-2013)“…Increasing evidence suggests that synchronization between brain regions is essential for information exchange and memory processes. However, it remains…”
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In vitro activation of the medial septum-Diagonal band complex generates atropine-sensitive and atropine-resistant hippocampal theta rhythm: An investigation using a complete septohippocampal preparation
Published in Hippocampus (01-06-2008)“…The medial septum and diagonal band complex (MS‐DB) is believed to play a key role in generating theta oscillations in the hippocampus, a phenomenon critical…”
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Network models provide insights into how oriens-lacunosum-moleculare and bistratified cell interactions influence the power of local hippocampal CA1 theta oscillations
Published in Frontiers in systems neuroscience (07-08-2015)“…Hippocampal theta is a 4-12 Hz rhythm associated with episodic memory, and although it has been studied extensively, the cellular mechanisms underlying its…”
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