Search Results - "Manook, Andre"

Classical Risk Factors and Inflammatory Biomarkers: One of the Missing Biological Links between Cardiovascular Disease and Major Depressive Disorder by Baghai, Thomas C, Varallo-Bedarida, Gabriella, Born, Christoph, Häfner, Sibylle, Schüle, Cornelius, Eser, Daniela, Zill, Peter, Manook, André, Weigl, Johannes, Jooyandeh, Somayeh, Nothdurfter, Caroline, von Schacky, Clemens, Bondy, Brigitta, Rupprecht, Rainer

“…Cardiovascular disorders (CVD) and major depressive disorder (MDD) are the most frequent diseases worldwide responsible for premature death and disability…”
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The cytokine IL‐17A as a marker of treatment resistance in major depressive disorder? by Nothdurfter, Caroline, Milenkovic, Vladimir M., Sarubin, Nina, Hilbert, Sven, Manook, André, Weigl, Johannes, Almeqbaali, Khalifa, Wetzel, Christian H., Rupprecht, Rainer, Baghai, Thomas C.

“…Major depression is a complex disease and—among others, inflammation appears to play an important role in its pathophysiology. In this study, we investigated a…”
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Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties by Triebelhorn, Julian, Cardon, Iseline, Kuffner, Kerstin, Bader, Stefanie, Jahner, Tatjana, Meindl, Katrin, Rothhammer-Hampl, Tanja, Riemenschneider, Markus J., Drexler, Konstantin, Berneburg, Mark, Nothdurfter, Caroline, Manook, André, Brochhausen, Christoph, Baghai, Thomas C., Hilbert, Sven, Rupprecht, Rainer, Milenkovic, Vladimir M., Wetzel, Christian H.

“…The molecular pathomechanisms of major depressive disorder (MDD) are still not completely understood. Here, we follow the hypothesis, that mitochondria…”
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Short-term effects of etifoxine on human gut microbiome in healthy men by Manook, André, Baghai, Thomas C, Riebel, Marco, Nothdurfter, Caroline, Schwarzbach, Jens Volkmar, Gessner, André, Rupprecht, Rainer, Hiergeist, Andreas

“…Neurosteroids have recently gained in interest as a treatment strategy for affective disorders. Etifoxine is known for its dual mode of action, one of which is…”
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Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease by Manook, André, Yousefi, Behrooz H, Willuweit, Antje, Platzer, Stefan, Reder, Sybille, Voss, Andreas, Huisman, Marc, Settles, Markus, Neff, Frauke, Velden, Joachim, Schoor, Michael, von der Kammer, Heinz, Wester, Hans-Jürgen, Schwaiger, Markus, Henriksen, Gjermund, Drzezga, Alexander

“…In vivo imaging and quantification of amyloid-β plaque (Aβ) burden in small-animal models of Alzheimer's disease (AD) is a valuable tool for translational…”
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Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis by Förstner, Bernd R., Tschorn, Mira, Reinoso-Schiller, Nicolas, Maričić, Lea Mascarell, Röcher, Erik, Kalman, Janos L., Stroth, Sanna, Mayer, Annalina V., Schwarz, Kristina, Kaiser, Anna, Pfennig, Andrea, Manook, André, Ising, Marcus, Heinig, Ingmar, Pittig, Andre, Heinz, Andreas, Mathiak, Klaus, Schulze, Thomas G., Schneider, Frank, Kamp-Becker, Inge, Meyer-Lindenberg, Andreas, Padberg, Frank, Banaschewski, Tobias, Bauer, Michael, Rupprecht, Rainer, Wittchen, Hans-Ulrich, Rapp, Michael A.

“…This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative…”
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Major Depressive Disorder is Associated with Impaired Mitochondrial Function in Skin Fibroblasts by Kuffner, Kerstin, Triebelhorn, Julian, Meindl, Katrin, Benner, Christoph, Manook, André, Sudria-Lopez, Daniel, Siebert, Ramona, Nothdurfter, Caroline, Baghai, Thomas C, Drexler, Konstantin, Berneburg, Mark, Rupprecht, Rainer, Milenkovic, Vladimir M, Wetzel, Christian H

“…Mitochondrial malfunction is supposed to be involved in the etiology and pathology of major depressive disorder (MDD). Here, we aimed to identify and…”
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The associations of Positive and Negative Valence Systems, Cognitive Systems and Social Processes on disease severity in anxiety and depressive disorders by Förstner, Bernd R, Böttger, Sarah Jane, Moldavski, Alexander, Bajbouj, Malek, Pfennig, Andrea, Manook, André, Ising, Marcus, Pittig, Andre, Heinig, Ingmar, Heinz, Andreas, Mathiak, Klaus, Schulze, Thomas G, Schneider, Frank, Kamp-Becker, Inge, Meyer-Lindenberg, Andreas, Padberg, Frank, Banaschewski, Tobias, Bauer, Michael, Rupprecht, Rainer, Wittchen, Hans-Ulrich, Rapp, Michael A, Tschorn, Mira

“…Anxiety and depressive disorders share common features of mood dysfunctions. This has stimulated interest in transdiagnostic dimensional research as proposed…”
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Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial by Hellmann-Regen, Julian, Clemens, Vera, Grözinger, Michael, Kornhuber, Johannes, Reif, Andreas, Prvulovic, David, Goya-Maldonado, Roberto, Wiltfang, Jens, Gruber, Oliver, Schüle, Cornelius, Padberg, Frank, Ising, Marcus, Uhr, Manfred, Friede, Tim, Huber, Cynthia, Manook, André, Baghai, Thomas C., Rupprecht, Rainer, Heuser, Isabella

“…ImportanceInsufficient treatment response and resulting chronicity constitute a major problem in depressive disorders. Remission rates range as low as 15% to…”
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Characterization and First Human Investigation of FIBT, a Novel Fluorinated Aβ Plaque Neuroimaging PET Radioligand by Hooshyar Yousefi, Behrooz, Manook, André, Grimmer, Timo, Arzberger, Thomas, von Reutern, Boris, Henriksen, Gjermund, Drzezga, Alexander, Förster, Stefan, Schwaiger, Markus, Wester, Hans-Jürgen

“…Imidazo[2,1-b]benzothiazoles (IBTs) are a promising novel class of amyloid positron emission tomography (PET) radiopharmaceuticals for diagnosis of…”
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FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice by Yousefi, Behrooz H, von Reutern, Boris, Scherübl, Daniela, Manook, André, Schwaiger, Markus, Grimmer, Timo, Henriksen, Gjermund, Förster, Stefan, Drzezga, Alexander, Wester, Hans-Jürgen

“…Background Over the last decade, an increasing number of studies have been published on the use of amyloid-β (Aβ) PET imaging with different 18…”
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Macrophage-Derived Chemokine: A Putative Marker of Pharmacological Therapy Response in Major Depression? by Milenkovic, Vladimir M, Sarubin, Nina, Hilbert, Sven, Baghai, Thomas C, Stöffler, Friederike, Lima-Ojeda, Juan M, Manook, André, Almeqbaali, Khalifa, Wetzel, Christian H, Rupprecht, Rainer, Nothdurfter, Caroline

“…Inflammatory processes play an important and complex role in the pathophysiology of major depressive disorder (MDD), but, so far, no specific investigation of…”
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Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease by Willuweit, Antje, Velden, Joachim, Godemann, Robert, Manook, Andre, Jetzek, Fritz, Tintrup, Hartmut, Kauselmann, Gunther, Zevnik, Branko, Henriksen, Gjermund, Drzezga, Alexander, Pohlner, Johannes, Schoor, Michael, Kemp, John A, von der Kammer, Heinz

“…Transgenic mice expressing mutated amyloid precursor protein (APP) and presenilin (PS)-1 or -2 have been successfully used to model cerebral beta-amyloidosis,…”
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Synthesis and Evaluation of 11C-Labeled Imidazo[2,1-b]benzothiazoles (IBTs) as PET Tracers for Imaging β-Amyloid Plaques in Alzheimer’s Disease by Yousefi, Behrooz H, Manook, André, Drzezga, Alexander, v. Reutern, Boris, Schwaiger, Markus, Wester, Hans-Jürgen, Henriksen, Gjermund

“…We report a novel series of 11C-labeled imidazo[2,1-b]benzothiazoles (IBTs) as tracers for imaging of cerebral β-amyloid (Aβ) deposits in patients with…”
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A Novel 18F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques by Yousefi, Behrooz H, Drzezga, Alexander, von Reutern, Boris, Manook, André, Schwaiger, Markus, Wester, Hans-Jürgen, Henriksen, Gjermund

“…18F-labeled imidazo[2,1-b]benzothiazole ([18F]8) was synthesized and evaluated as a tracer for cerebral β-amyloid deposits (Aβ) by means of positron emission…”
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A Novel (18)F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques by Yousefi, Behrooz H, Drzezga, Alexander, von Reutern, Boris, Manook, André, Schwaiger, Markus, Wester, Hans-Jürgen, Henriksen, Gjermund

“…(18)F-labeled imidazo[2,1-b]benzothiazole ([(18)F]8) was synthesized and evaluated as a tracer for cerebral β-amyloid deposits (Aβ) by means of positron…”
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Characterization of [F-18]FIBT, a highly selective and specific PET imaging agent for beta-amyloid plaques by Yousefi, Behrooz Hooshyar, Manook, André, von Reutern, Boris, Henriksen, Gjermund, Drzezga, Alexander, Wester, Hans-Juergen

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O2–11–01: Characterization of [F‐18]FIBT, a highly selective and specific PET imaging agent for beta‐amyloid plaques by Yousefi, Behrooz Hooshyar, Manook, André, Reutern, Boris, Henriksen, Gjermund, Drzezga, Alexander, Wester, Hans‐Juergen

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Synthesis and Evaluation of 11 C-Labeled Imidazo[2,1- b ]benzothiazoles (IBTs) as PET Tracers for Imaging β-Amyloid Plaques in Alzheimer’s Disease by Yousefi, Behrooz H., Manook, André, Drzezga, Alexander, v. Reutern, Boris, Schwaiger, Markus, Wester, Hans-Jürgen, Henriksen, Gjermund

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A Novel 18 F-Labeled Imidazo[2,1- b ]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques by Yousefi, Behrooz H., Drzezga, Alexander, von Reutern, Boris, Manook, André, Schwaiger, Markus, Wester, Hans-Jürgen, Henriksen, Gjermund

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